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TGen @tgenresearch.bsky.social · 5d

Congratulations to TGen - Part of City of Hope clinical professor, Vinodh Narayanan, M.D., on receiving the Roger and Mary Brumback Lifetime Achievement Award at the 2025 Child Neurology Society Meeting.

Photo credit: Keri Ramsey

TGen @tgenresearch.bsky.social · 10d

@tgenresearch.bsky.social partners to release new technology with @googleresearch.bsky.social and @ucscgenomics.bsky.social: DeepSomatic 🧑🏽‍💻 This #machinelearning method is a major leap forward for #cancer mutation #detection. More at bit.ly/4nYDDJY and lnkd.in/gQA4frVa
#Research #Genomics

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Nick Banovich @nebanovich.bsky.social · 16d

Great presentations from the lab this week at #ashg25.

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TGen @tgenresearch.bsky.social · Sep 16

For #postdoc appreciation week, we sat down with Dr. Aya Kamzinain the Division of Early Detection and Prevention at TGen, to learn more about her work and role as a postdoc. Full blog at bit.ly/48jnkT6
#Science #Research #Impact #Thoughtleader #Genomics #foryoupage #fyp

Reposted by TGen

Jonathan Keats, PhD 🇨🇦 @pedalheadphx.bsky.social · Sep 6

Interesting @nebanovich.bsky.social @florisbarthel.bsky.social glad we just installed an @elembio.bsky.social Aviti24 @tgenresearch.bsky.social. @aphillippy.bsky.social is this with standard cloudbreak chemistry or the high accuracy ultraQ chemistry

Adam Phillippy @aphillippy.bsky.social · Sep 5

Definitely hard to measure, but here is our best attempt from a new benchmarking paper to be preprinted in the next few weeks. Element appears to be the current king of homopolymers. Illumina does worse than HiFi beyond 20 bp. (This is all measured on human DNA)

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TGen @tgenresearch.bsky.social · Sep 8

Researchers have identified 2 proteins that could serve as new biomarkers for #pancreatic #cancer. These protein markers can help distinguish cancer from non-cancer and track how patients are responding to treatment. This offers a new direction for the early detection & monitoring. bit.ly/4mbboX0

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Nick Banovich @nebanovich.bsky.social · Aug 1

Yesterday was the last day of @tgenresearch.bsky.social's summer internship supported by the Helios foundation. Bittersweet to say goodbye but happy to see them presenting their great work. Special congrats to Francesca, Lauren, and Yafnelt who were recognized for their outstanding presentations.

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TGen @tgenresearch.bsky.social · Jul 25

Full journal article at bit.ly/4mdoljt

Frontiers | NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer

IntroductionImmune-based agents, especially Immune Checkpoint Inhibitors (ICI), are standard of care therapy in non-small cell lung cancers (NSCLC); however,...

bit.ly

TGen @tgenresearch.bsky.social · Jul 25

Breakthrough news in the fight against lung cancer! 🚨 A new study shows how molecules from a patient's own immune cells (natural killer cells) could reawaken the body's defenses to combat tough tumors for hard-to-treat lung cancers; harnessing the body's own natural killer cells to fight back.

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TGen @tgenresearch.bsky.social · Jul 11

Building the evidence base for engaging all populations in genomics research is key for Participant Engagement and Cancer Genome Sequencing Network (PE-CGS). The newest paper introduces a new framework & strategies for involving community members in #cancer #genomics #research. lnkd.in/gjj-WQ8n

Reposted by TGen

Jonathan Keats, PhD 🇨🇦 @pedalheadphx.bsky.social · Jul 3

But not all mutations block all anti-BCMA therapies from binding and we at @tgenresearch.bsky.social and @cityofhope.bsky.social are integrating the known binding of these agents into our whole genome sequencing reports to ensure patients get the therapy that will work best for them at that point

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Jonathan Keats, PhD 🇨🇦 @pedalheadphx.bsky.social · Jun 7

ascopubs.org/doi/10.1200/... considering the patient population this is extremely impressive, 1/3 of patients progression free at 5 years, glad to have @cityofhope.bsky.social physician Dr. Myo Htut as one of the coauthors. I for one believe cures are possible in #myeloma @tgenresearch.bsky.social

Long-Term (≥5-Year) Remission and Survival After Treatment With Ciltacabtagene Autoleucel in CARTITUDE-1 Patients With Relapsed/Refractory Multiple Myeloma

CARTITUDE-1 evaluated ciltacabtagene autoleucel (cilta-cel) in patients with heavily pretreated relapsed/refractory multiple myeloma (RRMM). We describe overall survival (OS), ≥5-year progression-free...

ascopubs.org

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TGen @tgenresearch.bsky.social · May 23

TGen scientists have found a new weakness in a rare ovarian cancer that might help us treat it better. This could mean new and improved treatments are on the way, even for cancers that were hard to treat before. More at www.tgen.org/news/study-r.... #OvarianCancer #Research

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TGen @tgenresearch.bsky.social · May 22

2/2This study is a big step towards:
💡 Understanding liver disease better, especially in people who might not seem at risk
🔍 Catching problems earlier and helps prevent serious health problems in the future - Such as Liver Cancer, Liver Failure, Cirrhosis, and other related diseases like diabetes.

TGen @tgenresearch.bsky.social · May 22

Liver disease can affect anyone, not just those who are overweight 🤔 A Study found that even healthy-weight people can have fat in their liver, & it might be because of their genes. Learning about these genes can help doctors figure out who's at risk & improve care for everyone.
bit.ly/3YURmas

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TGen @tgenresearch.bsky.social · May 19

Where science meets business🤝An insider’s perspective on how today’s #biomedical research translates into tomorrow's treatments. Stephanie Pond, Ph.D., shared how her team works to identify gaps in current research tools, & help commercialize TGen’s research discoveries. Listen today🎙️ bit.ly/3YYzjzU

TGen @tgenresearch.bsky.social · May 12

4️⃣ things #emerging #scientists should do as they prepare for a role in research. Ignazio S Piras, Ph.D., shares tips for preparing for a world in research, and how having a unique educational background has allowed him to participate in a wide variety of projects.
www.linkedin.com/.../world-wi...

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TGen @tgenresearch.bsky.social · Apr 28

Congratulations to Daniel D. Von Hoff, M.D., F.A.C.P., distinguished professor at TGen and @cityofhope.bsky.social, on being recognized at the #AACR25 Partners in Progress Reception for his immeasurable contributions to AACR, cancer research and patient care!

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TGen @tgenresearch.bsky.social · Apr 25

🧬 Today is National DNA Day 🧬
We wouldn't be where we are today without the hard work of Friedrich Miescher (1869) and Rosalind Franklin, James Watson, and Francis Crick (1953). Thanks to their contributions, the foundation of genetics and genomic sciences is strong.

TGen @tgenresearch.bsky.social · Apr 23

TGen is proud to present at the 2025 @theaacr.bsky.social Annual Meeting.

Be sure to stop by the @cityofhope.bsky.social and TGen booth at the Exhibit Hall from April 27 - 30.

#AACR25 #Cancer #Research

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TGen @tgenresearch.bsky.social · Apr 18

💡Remarkable Research💡The #MindCrowd mobile lab is a unique research project bringing the lab to the community. Research can be scary & hard to find the time to participate, so the MindCrowd team goes to communities allowing individuals to be a part of brain research. More at tgen.org/mindcrowd 🧠

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Jonathan Keats, PhD 🇨🇦 @pedalheadphx.bsky.social · Apr 17

Great work on whole genome assembly using @nanoporetech.com and @pacbio.bsky.social sequencing @tgenresearch.bsky.social part of @cityofhope.bsky.social

Floris Barthel @florisbarthel.bsky.social · Apr 16

But mostly, massive credit to first authors @trhyker.bsky.social + @yuehao.bsky.social , and co-authors @pedalheadphx.bsky.social @mishakolmogorov.bsky.social @benedictpaten.bsky.social @mitchiela.bsky.social @msstephkayb.bsky.social + others not on here (yet) 🙏

🔗 www.biorxiv.org/content/10.1...

Diploid genome assembly of human fibroblast cell lines enables clone specific variant calling, improved read mapping and accurate phasing

Human cell lines are fundamental tools in biomedical research and are widely used in disease modeling, drug development, and many other domains. Here, we present chromosome-level, phased diploid genom...

www.biorxiv.org

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TGen @tgenresearch.bsky.social · Apr 14

www.linkedin.com/pulse/naviga...

#Science #Research #Impact #Technology #ComputationalScientist #Genomics #Collaboration #TGen #CityofHope

Navigating the Frontiers of Science: A Journey in Computational Biology with Heini Natri

Author – TGen Heini M. Natri, Ph.

www.linkedin.com

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TGen @tgenresearch.bsky.social · Apr 14

💡 "Good researchers and leaders figure out the right questions to ask." 💡Meet Dr. @heinimnatri.bsky.social, Research Assistant Professor. She shares insights on team science, mentorship, & her recent breakthrough in glioblastoma research—helping pave the way for new clinical trials in CAR T therapy.

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TGen @tgenresearch.bsky.social · Apr 11

#PulmonaryFibrosis #LungHealth #Research #TGenTalks #Podcast

The TGen Talks Podcast

www.tgen.org