Therapeutic Advances in Neurological Disorders
@taneuroldisord.bsky.social
A leading gold #OpenAccess journal in clinical neurology | IF 4.1 CiteScore 8.5 | 🧠 Follow us for neurological research and news.
Reposted by Therapeutic Advances in Neurological Disorders
📣 New publication: How are brain volumes affected in patients with AQP4-IgG+ NMOSD?
It’s a magnificent Monday to share our new #metaanalysis on structural #MRI findings in #NMOSD in @taneuroldisord.bsky.social.
🧵 A thread.
journals.sagepub.com/doi/10.1177/...
It’s a magnificent Monday to share our new #metaanalysis on structural #MRI findings in #NMOSD in @taneuroldisord.bsky.social.
🧵 A thread.
journals.sagepub.com/doi/10.1177/...
Brain volumetry and spinal cord imaging in patients with AQP4-IgG+ NMOSD—a systematic review and meta-analysis - Josephine Heine, Claudia Chien, 2025
Background: Magnetic resonance imaging (MRI) is often used to evaluate disease-related brain changes in patients with aquaporin-4-IgG seropositive neuromyelitis...
journals.sagepub.com
December 8, 2025 at 10:34 PM
📣 New publication: How are brain volumes affected in patients with AQP4-IgG+ NMOSD?
It’s a magnificent Monday to share our new #metaanalysis on structural #MRI findings in #NMOSD in @taneuroldisord.bsky.social.
🧵 A thread.
journals.sagepub.com/doi/10.1177/...
It’s a magnificent Monday to share our new #metaanalysis on structural #MRI findings in #NMOSD in @taneuroldisord.bsky.social.
🧵 A thread.
journals.sagepub.com/doi/10.1177/...
What are the clinical factors associated with perampanel retention, response, seizure freedom and tolerability?
Find out more in this pooled analysis from 6800 people with #epilepsy: journals.sagepub.com/doi/full/10....
Find out more in this pooled analysis from 6800 people with #epilepsy: journals.sagepub.com/doi/full/10....
December 9, 2025 at 11:56 AM
What are the clinical factors associated with perampanel retention, response, seizure freedom and tolerability?
Find out more in this pooled analysis from 6800 people with #epilepsy: journals.sagepub.com/doi/full/10....
Find out more in this pooled analysis from 6800 people with #epilepsy: journals.sagepub.com/doi/full/10....
How safe and effective is efgartigimod in seronegative #MyastheniaGravis?
Results from a 6-month open-label study here:
journals.sagepub.com/doi/pdf/10.1...
Results from a 6-month open-label study here:
journals.sagepub.com/doi/pdf/10.1...
December 5, 2025 at 12:57 PM
How safe and effective is efgartigimod in seronegative #MyastheniaGravis?
Results from a 6-month open-label study here:
journals.sagepub.com/doi/pdf/10.1...
Results from a 6-month open-label study here:
journals.sagepub.com/doi/pdf/10.1...
Could botulinum toxin serve as an adjunct therapy in stiff person syndrome spectrum disorders?
New research by Samantha Roman and colleagues:
journals.sagepub.com/doi/full/10....
New research by Samantha Roman and colleagues:
journals.sagepub.com/doi/full/10....
December 4, 2025 at 10:12 AM
Could botulinum toxin serve as an adjunct therapy in stiff person syndrome spectrum disorders?
New research by Samantha Roman and colleagues:
journals.sagepub.com/doi/full/10....
New research by Samantha Roman and colleagues:
journals.sagepub.com/doi/full/10....
How to manage immunosuppressant treatment during pregnancy and avoid postpartum relapse in patients with neuromyelitis optica spectrum disorder (NMOSD)?
Read this new Review by Yuko Shimizu and colleagues to learn more: journals.sagepub.com/doi/full/10....
Read this new Review by Yuko Shimizu and colleagues to learn more: journals.sagepub.com/doi/full/10....
December 3, 2025 at 10:37 AM
How to manage immunosuppressant treatment during pregnancy and avoid postpartum relapse in patients with neuromyelitis optica spectrum disorder (NMOSD)?
Read this new Review by Yuko Shimizu and colleagues to learn more: journals.sagepub.com/doi/full/10....
Read this new Review by Yuko Shimizu and colleagues to learn more: journals.sagepub.com/doi/full/10....
Could GLP-1 receptor agonists be a therapeutic option for idiopathic intracranial hypertension?
This new Systematic Review & Meta-Analysis summarizes current state of evidence:
journals.sagepub.com/doi/full/10....
This new Systematic Review & Meta-Analysis summarizes current state of evidence:
journals.sagepub.com/doi/full/10....
December 2, 2025 at 11:21 AM
Could GLP-1 receptor agonists be a therapeutic option for idiopathic intracranial hypertension?
This new Systematic Review & Meta-Analysis summarizes current state of evidence:
journals.sagepub.com/doi/full/10....
This new Systematic Review & Meta-Analysis summarizes current state of evidence:
journals.sagepub.com/doi/full/10....
New from our Special Collection on Autoimmune Neurology and Paraneoplastic Neurologic Syndromes!
Immune checkpoint inhibitor therapy can lead to anti-Yo antibody development.
Farina et al describe the clinical and tumor features in some of these patients: journals.sagepub.com/doi/full/10....
Immune checkpoint inhibitor therapy can lead to anti-Yo antibody development.
Farina et al describe the clinical and tumor features in some of these patients: journals.sagepub.com/doi/full/10....
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December 1, 2025 at 4:43 PM
New from our Special Collection on Autoimmune Neurology and Paraneoplastic Neurologic Syndromes!
Immune checkpoint inhibitor therapy can lead to anti-Yo antibody development.
Farina et al describe the clinical and tumor features in some of these patients: journals.sagepub.com/doi/full/10....
Immune checkpoint inhibitor therapy can lead to anti-Yo antibody development.
Farina et al describe the clinical and tumor features in some of these patients: journals.sagepub.com/doi/full/10....
We'll soon be covering the promise of CAR T-cells in autoimmune neurological disorders in our dedicated Special Collection, Guest Edited by Professor Marinos Dalakas.
In the meantime, you can learn about this emerging treatment modality for autoimmune disease here:
www.nature.com/articles/d41...
In the meantime, you can learn about this emerging treatment modality for autoimmune disease here:
www.nature.com/articles/d41...
‘They don’t have symptoms’: CAR-T therapies send autoimmune diseases into remission
Engineered T cells that have been used to treat ulcerative colitis, rheumatoid arthritis and lupus show promising results.
www.nature.com
November 28, 2025 at 12:49 PM
We'll soon be covering the promise of CAR T-cells in autoimmune neurological disorders in our dedicated Special Collection, Guest Edited by Professor Marinos Dalakas.
In the meantime, you can learn about this emerging treatment modality for autoimmune disease here:
www.nature.com/articles/d41...
In the meantime, you can learn about this emerging treatment modality for autoimmune disease here:
www.nature.com/articles/d41...
New real-life cohort study from Argentina compares the aspects of subcutaneous vs intravenous #natalizumab in #MultipleSclerosis:
journals.sagepub.com/doi/full/10....
journals.sagepub.com/doi/full/10....
November 28, 2025 at 11:56 AM
New real-life cohort study from Argentina compares the aspects of subcutaneous vs intravenous #natalizumab in #MultipleSclerosis:
journals.sagepub.com/doi/full/10....
journals.sagepub.com/doi/full/10....
Ofatumumab is approved for adults with #MultipleSclerosis - but what is its utility in pediatric patients?
Wenlin Wu and colleagues present Case Series data from four pediatric patients:
journals.sagepub.com/doi/full/10....
Wenlin Wu and colleagues present Case Series data from four pediatric patients:
journals.sagepub.com/doi/full/10....
November 27, 2025 at 11:43 AM
Ofatumumab is approved for adults with #MultipleSclerosis - but what is its utility in pediatric patients?
Wenlin Wu and colleagues present Case Series data from four pediatric patients:
journals.sagepub.com/doi/full/10....
Wenlin Wu and colleagues present Case Series data from four pediatric patients:
journals.sagepub.com/doi/full/10....
Can a mobile app facilitate digital documentation and communication in acute #stroke, and improve documentation rates and treatment times?
Stevens and colleagues designed a pilot study to find out:
journals.sagepub.com/doi/full/10....
Stevens and colleagues designed a pilot study to find out:
journals.sagepub.com/doi/full/10....
November 26, 2025 at 3:55 PM
Can a mobile app facilitate digital documentation and communication in acute #stroke, and improve documentation rates and treatment times?
Stevens and colleagues designed a pilot study to find out:
journals.sagepub.com/doi/full/10....
Stevens and colleagues designed a pilot study to find out:
journals.sagepub.com/doi/full/10....
Could brain natriuretic peptide and echocardiographic parameters serve as biomarkers for predicting new atrial fibrillation after acute ischemic stroke?
Stefano Forlivesi and colleagues investigate:
journals.sagepub.com/doi/full/10....
#Stroke #AFib
Stefano Forlivesi and colleagues investigate:
journals.sagepub.com/doi/full/10....
#Stroke #AFib
November 25, 2025 at 3:25 PM
Could brain natriuretic peptide and echocardiographic parameters serve as biomarkers for predicting new atrial fibrillation after acute ischemic stroke?
Stefano Forlivesi and colleagues investigate:
journals.sagepub.com/doi/full/10....
#Stroke #AFib
Stefano Forlivesi and colleagues investigate:
journals.sagepub.com/doi/full/10....
#Stroke #AFib
New from our Special Collection on
Innovative treatments for migraine: a new era
Here, Katsuki and colleagues present trends in real-world use of #lasmiditan for migraine in Japan, using nationwide health insurance claims data.
journals.sagepub.com/doi/full/10....
Innovative treatments for migraine: a new era
Here, Katsuki and colleagues present trends in real-world use of #lasmiditan for migraine in Japan, using nationwide health insurance claims data.
journals.sagepub.com/doi/full/10....
November 24, 2025 at 10:35 AM
New from our Special Collection on
Innovative treatments for migraine: a new era
Here, Katsuki and colleagues present trends in real-world use of #lasmiditan for migraine in Japan, using nationwide health insurance claims data.
journals.sagepub.com/doi/full/10....
Innovative treatments for migraine: a new era
Here, Katsuki and colleagues present trends in real-world use of #lasmiditan for migraine in Japan, using nationwide health insurance claims data.
journals.sagepub.com/doi/full/10....
New #SystematicReview from our Special Collection on Neuromyelitis Optica Spectrum Disorders:
Which environmental risk factors influence the onset of the disease?
Find out more here: journals.sagepub.com/doi/full/10....
Which environmental risk factors influence the onset of the disease?
Find out more here: journals.sagepub.com/doi/full/10....
Environmental risk factors of neuromyelitis optica spectrum disorder: a systematic review - Mahsa Mohammadi Lapevandani, Elham Bazmi, Shima Jahani, Nasrin Asgari, Mohammad Ali Sahraian, 2025
Background: Neuromyelitis optica spectrum disorder (NMOSD) may be triggered by environmental risk factors. Objectives: We aimed to explore and integrate the re...
journals.sagepub.com
November 21, 2025 at 9:49 AM
New #SystematicReview from our Special Collection on Neuromyelitis Optica Spectrum Disorders:
Which environmental risk factors influence the onset of the disease?
Find out more here: journals.sagepub.com/doi/full/10....
Which environmental risk factors influence the onset of the disease?
Find out more here: journals.sagepub.com/doi/full/10....
Posterior circulation stroke: What predicts recovery after thrombectomy?
Post hoc analysis of 353 patients shows 24-h NIHSS ≤9 is the strongest predictor of favorable 90-day mRS.
ΔNIHSS and % change less reliable. #Stroke journals.sagepub.com/doi/full/10....
Post hoc analysis of 353 patients shows 24-h NIHSS ≤9 is the strongest predictor of favorable 90-day mRS.
ΔNIHSS and % change less reliable. #Stroke journals.sagepub.com/doi/full/10....
November 20, 2025 at 10:23 AM
Posterior circulation stroke: What predicts recovery after thrombectomy?
Post hoc analysis of 353 patients shows 24-h NIHSS ≤9 is the strongest predictor of favorable 90-day mRS.
ΔNIHSS and % change less reliable. #Stroke journals.sagepub.com/doi/full/10....
Post hoc analysis of 353 patients shows 24-h NIHSS ≤9 is the strongest predictor of favorable 90-day mRS.
ΔNIHSS and % change less reliable. #Stroke journals.sagepub.com/doi/full/10....
New Case Series online:
#Migraine with brainstem aura with abnormal EEG discharges easily misdiagnosed as epilepsy
journals.sagepub.com/doi/full/10....
#Migraine with brainstem aura with abnormal EEG discharges easily misdiagnosed as epilepsy
journals.sagepub.com/doi/full/10....
November 19, 2025 at 9:30 AM
New Case Series online:
#Migraine with brainstem aura with abnormal EEG discharges easily misdiagnosed as epilepsy
journals.sagepub.com/doi/full/10....
#Migraine with brainstem aura with abnormal EEG discharges easily misdiagnosed as epilepsy
journals.sagepub.com/doi/full/10....
New article in our Special Collection: New Frontiers in Acute Reperfusion Therapies for Acute Ischemic Stroke
This Review synthesizes evidence for the effectiveness of "Drip & Ship" model in acute #stroke care: 🚑
journals.sagepub.com/doi/full/10....
This Review synthesizes evidence for the effectiveness of "Drip & Ship" model in acute #stroke care: 🚑
journals.sagepub.com/doi/full/10....
November 18, 2025 at 9:53 AM
New article in our Special Collection: New Frontiers in Acute Reperfusion Therapies for Acute Ischemic Stroke
This Review synthesizes evidence for the effectiveness of "Drip & Ship" model in acute #stroke care: 🚑
journals.sagepub.com/doi/full/10....
This Review synthesizes evidence for the effectiveness of "Drip & Ship" model in acute #stroke care: 🚑
journals.sagepub.com/doi/full/10....
Could #MultipleSclerosis phenotypic profiles be distinguishable at diagnosis?
Aurora Zanghi and colleagues use a multimodal #biomarker approach to investigate:
journals.sagepub.com/doi/full/10....
Aurora Zanghi and colleagues use a multimodal #biomarker approach to investigate:
journals.sagepub.com/doi/full/10....
November 14, 2025 at 12:14 PM
Could #MultipleSclerosis phenotypic profiles be distinguishable at diagnosis?
Aurora Zanghi and colleagues use a multimodal #biomarker approach to investigate:
journals.sagepub.com/doi/full/10....
Aurora Zanghi and colleagues use a multimodal #biomarker approach to investigate:
journals.sagepub.com/doi/full/10....
Is increased middle cerebral artery peak systolic velocity associated with the development of malignant media infarction after endovascular thrombectomy?
Find out more in this study, recently published in Therapeutic Advances in Neurological Disorders: #stroke
journals.sagepub.com/doi/full/10....
Find out more in this study, recently published in Therapeutic Advances in Neurological Disorders: #stroke
journals.sagepub.com/doi/full/10....
November 13, 2025 at 9:29 AM
Is increased middle cerebral artery peak systolic velocity associated with the development of malignant media infarction after endovascular thrombectomy?
Find out more in this study, recently published in Therapeutic Advances in Neurological Disorders: #stroke
journals.sagepub.com/doi/full/10....
Find out more in this study, recently published in Therapeutic Advances in Neurological Disorders: #stroke
journals.sagepub.com/doi/full/10....
A new RCT online!
Lisa Schäfer and colleagues show how multidisciplinary online care can improve mental health, vitality, and quality of life in women with X-linked adrenoleukodystrophy - a model that could be scaled for other rare disorders.
#RareDisease
journals.sagepub.com/doi/pdf/10.1...
Lisa Schäfer and colleagues show how multidisciplinary online care can improve mental health, vitality, and quality of life in women with X-linked adrenoleukodystrophy - a model that could be scaled for other rare disorders.
#RareDisease
journals.sagepub.com/doi/pdf/10.1...
November 12, 2025 at 10:29 AM
A new RCT online!
Lisa Schäfer and colleagues show how multidisciplinary online care can improve mental health, vitality, and quality of life in women with X-linked adrenoleukodystrophy - a model that could be scaled for other rare disorders.
#RareDisease
journals.sagepub.com/doi/pdf/10.1...
Lisa Schäfer and colleagues show how multidisciplinary online care can improve mental health, vitality, and quality of life in women with X-linked adrenoleukodystrophy - a model that could be scaled for other rare disorders.
#RareDisease
journals.sagepub.com/doi/pdf/10.1...
New study by Matteo Foschi et al reveals sex-specific patterns in #MultipleSclerosis progression:
Women—especially postmenopausal—face higher risk of disability worsening independent of relapses, while men experience greater impact per event:
journals.sagepub.com/doi/full/10....
Women—especially postmenopausal—face higher risk of disability worsening independent of relapses, while men experience greater impact per event:
journals.sagepub.com/doi/full/10....
November 11, 2025 at 10:09 AM
New study by Matteo Foschi et al reveals sex-specific patterns in #MultipleSclerosis progression:
Women—especially postmenopausal—face higher risk of disability worsening independent of relapses, while men experience greater impact per event:
journals.sagepub.com/doi/full/10....
Women—especially postmenopausal—face higher risk of disability worsening independent of relapses, while men experience greater impact per event:
journals.sagepub.com/doi/full/10....
New Review online!
Here, Joost Smolders and colleagues argue that aggressive treatment of early acute focal inflammatory activity in #MultipleSclerosis can extend the window for BTK inhibition and slow down progression
journals.sagepub.com/doi/full/10....
Here, Joost Smolders and colleagues argue that aggressive treatment of early acute focal inflammatory activity in #MultipleSclerosis can extend the window for BTK inhibition and slow down progression
journals.sagepub.com/doi/full/10....
November 10, 2025 at 4:03 PM
New Review online!
Here, Joost Smolders and colleagues argue that aggressive treatment of early acute focal inflammatory activity in #MultipleSclerosis can extend the window for BTK inhibition and slow down progression
journals.sagepub.com/doi/full/10....
Here, Joost Smolders and colleagues argue that aggressive treatment of early acute focal inflammatory activity in #MultipleSclerosis can extend the window for BTK inhibition and slow down progression
journals.sagepub.com/doi/full/10....
New Review online!
Here, Wolfgang Jost and Jiri Koschel discuss approaches for diagnosing and treating cardiovascular symptoms in #Parkinson’s disease:
journals.sagepub.com/doi/full/10....
Here, Wolfgang Jost and Jiri Koschel discuss approaches for diagnosing and treating cardiovascular symptoms in #Parkinson’s disease:
journals.sagepub.com/doi/full/10....
November 6, 2025 at 10:42 AM
New Review online!
Here, Wolfgang Jost and Jiri Koschel discuss approaches for diagnosing and treating cardiovascular symptoms in #Parkinson’s disease:
journals.sagepub.com/doi/full/10....
Here, Wolfgang Jost and Jiri Koschel discuss approaches for diagnosing and treating cardiovascular symptoms in #Parkinson’s disease:
journals.sagepub.com/doi/full/10....
🧠 20 years of #natalizumab in #MultipleSclerosis care:
A new Review reflects on two decades of clinical experience with natalizumab—its efficacy, safety, and evolving role in treatment strategies.
📖 Read this Open Access article here: doi.org/10.1177/1756...
A new Review reflects on two decades of clinical experience with natalizumab—its efficacy, safety, and evolving role in treatment strategies.
📖 Read this Open Access article here: doi.org/10.1177/1756...
November 5, 2025 at 11:18 AM
🧠 20 years of #natalizumab in #MultipleSclerosis care:
A new Review reflects on two decades of clinical experience with natalizumab—its efficacy, safety, and evolving role in treatment strategies.
📖 Read this Open Access article here: doi.org/10.1177/1756...
A new Review reflects on two decades of clinical experience with natalizumab—its efficacy, safety, and evolving role in treatment strategies.
📖 Read this Open Access article here: doi.org/10.1177/1756...
Elevated liver enzymes (AST, ALT, GGT) may correlate with lower #migraine prevalence—especially migraines without aura.
Could glutamate regulation be a metabolic clue in migraine pathology?
New study by Angela Ruban and colleagues:
journals.sagepub.com/doi/full/10....
Could glutamate regulation be a metabolic clue in migraine pathology?
New study by Angela Ruban and colleagues:
journals.sagepub.com/doi/full/10....
November 4, 2025 at 11:33 AM
Elevated liver enzymes (AST, ALT, GGT) may correlate with lower #migraine prevalence—especially migraines without aura.
Could glutamate regulation be a metabolic clue in migraine pathology?
New study by Angela Ruban and colleagues:
journals.sagepub.com/doi/full/10....
Could glutamate regulation be a metabolic clue in migraine pathology?
New study by Angela Ruban and colleagues:
journals.sagepub.com/doi/full/10....