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rPeptide
@rpeptide.bsky.social
R&D Starts Here! Recombinant peptides, proteins, antibodies, reagents, and custom services for Alzheimer’s, Parkinson’s, and other neurodegenerative research.
Don't forget your water! Even mild dehydration can reduce focus, memory, and alertness.💧🧠

#BrainFuel #ScienceFacts #Hydration #rPeptide
December 8, 2025 at 3:50 PM
Your brain rewires—not just in youth, but at age 9, 32, 66, and 83! 🧠

New study maps five major brain-aging epochs across the human lifespan.

t.ly/rVaVE

#Neuroscience #BrainHealth #Aging
Your Brain Quietly Rewires Itself at 9, 32, 66 and 83 - Neuroscience News
Researchers identified five major phases of human brain wiring that unfold from birth to old age, marked by four major turning points at ages 9, 32, 66, and 83.
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December 5, 2025 at 1:36 PM
Could the immune system help slow Parkinson’s progression?

A new study suggests yes — thanks to dendritic cells expressing Clec5a, which reduced inflammation and protected vulnerable neurons.

t.ly/bIlDz

#ParkinsonsDisease #Neurodegeneration #ResearchUpdate #rPeptide
Dendritic Cells Induce Clec5a-mediated Immune Modulation in MPTP-induced Parkinson's Disease Mouse Model - PubMed
These findings suggest that Clec5a plays a critical role in the immunomodulatory function of tolDCs. The administration of Clec5a-expressing DCs effectively reduced neuroinflammation and protected dopaminergic neurons in an MPTP-induced PD model. Therefore, Clec5a-expressing tolDCs may demonstrate t …
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December 3, 2025 at 1:31 PM
Because even Fibrils need a little strength training to stay aggregated! 🏋️‍♂️🧬

#ScienceHumor #NeuroScience #ResearchLife #rPeptide
December 1, 2025 at 2:52 PM
Our November Raffle Riddle winner is Sidney! 🎉

Please check your email to claim your prize.

Thank you to everyone who participated!

#WinnerAnnouncement #rPeptide #Raffle #Prize
November 28, 2025 at 2:15 PM
A quiet hero of every experiment: A Control Group! 🙌

#ScienceRiddle #LabLife #ResearchTools #ScienceCommunity #rPeptide
November 26, 2025 at 1:30 PM
A new Nature study shows an Alzheimer’s risk variant disrupts microglia, causing lipid-droplet buildup and poor amyloid-β clearance.

Researchers used rPeptide’s Aβ (1–42) Aggregation Kit to generate fibrils for testing.

t.ly/y1hR8

#Neuroscience #AlzheimersResearch #Microglia
PICALM Alzheimer’s risk allele causes aberrant lipid droplets in microglia - Nature
A PICALM allele associated with increased risk of late-onset Alzheimer’s disease has a microglial-specific role in lipid droplet accumulation.
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November 24, 2025 at 4:14 PM
Listening to music every day might lower dementia risk by nearly 40%.

A simple and fun habit with a big impact. 🎧✨

Science continually reminds us of the profound connection between our senses, emotions, and brain health.

t.ly/v9jFe

#BrainHealth #NeuroscienceNews #DementiaAwareness #rPeptide
Daily music listening linked to big drop in dementia risk
Older adults who regularly listen to or play music appear to have significantly lower risks of dementia and cognitive decline. The data suggests that musical engagement could be a powerful, enjoyable ...
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November 21, 2025 at 1:27 PM
This month’s riddle hides in every experiment…

Can you spot it? 🔎

#ScienceRiddle #LabLife #ResearchCommunity #ScienceHumor #rPeptide
November 19, 2025 at 1:07 PM
Researchers developed a DNA aptamer–based column that can capture and concentrate Aβ40 and Aβ42 from spinal fluid with high precision.

To optimize the method, they used rPeptide’s Aβ1-38, Aβ1-40, Aβ1-42, and N15-labeled peptides.

t.ly/oUEey

#Neuroscience #AlzheimersResearch #rPeptide
Synthesis and characterization of miniaturized aptamer-based monolithic sorbent for selective extraction of β-amyloid peptides from cerebrospinal fluid
The ratio between beta-amyloid (Aβ) peptides 40 and 42 is recognized as a biomarker for Alzheimer's disease, playing a significant role in early diagnosis and disease progression monitoring. Aβ peptides are present at trace levels in cerebrospinal ...
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November 17, 2025 at 3:53 PM
Keeping our priorities straight… one magnified moment at a time. 🔬✨

Stay focused, stay curious!

#ScienceHumor #LabLife #FridayFunny #rPeptide
November 14, 2025 at 1:54 PM
Tau buildup doesn’t just mark disease—it changes how neurons talk. 🧠

Using rPeptide’s Tau-441 PFFs, researchers found Tau aggregates shift brain signaling toward long-term depression, mirroring early Alzheimer’s disruptions.

t.ly/SmJ7G

#Neuroscience #TauProtein #AlzheimersResearch #rPeptide
Incubation with tau aggregates increases hippocampal circuit excitability and enhances long-term depression in acute mouse hippocampal slices
Aggregation of the protein tau is a key pathological hallmark of tauopathies such as Alzheimer’s Disease. Tau dissociates from microtubules and diffuses from the axon into the soma-dendritic compartment, where it aggregates firstly into oligomers ...
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November 12, 2025 at 1:12 PM
Spending time in nature reduces stress hormones and boosts cognitive focus! 🌳✨

#MindfulMoments #BrainHealth #rPeptide
November 10, 2025 at 5:49 PM
Discovery isn’t confined to the lab — it’s a way of seeing the world! 🌍✨

#EverydayScience #ScienceConnectsUs #InspiringMinds #rPeptide
November 7, 2025 at 2:32 PM
A new study shows Khaya grandifoliola bark extracts can reduce βA 1-42 aggregation and target multiple disease pathways.

rPeptide’s #BetaAmyloid (1-42) was used to track fibrillation, highlighting plant-based promise in neurodegeneration research.

t.ly/nmxNM

#Neuroscience #Research #rPeptide
Khaya grandifololia exerts multitarget neuroprotective potential against neurodegenerative disorders: In vitro and in silico studies
Treatment for complex multifactorial neurological disorders may benefit more from multifunctional chemicals. Dysregulation of monoaminergic pathways a…
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November 5, 2025 at 1:46 PM
Researchers found that by tweaking a key clock protein (REV-ERBα) in mice, brain levels of NAD+ went up and harmful tau buildup—a hallmark of #Alzheimers disease — went down.

Adjusting your internal rhythm may one day help protect your brain.

t.ly/xYCMQ

#Tau #Neuroscience #rPeptide
Resetting the body’s rhythm could protect the brain from Alzheimer’s
Researchers discovered that altering the body’s natural rhythm can help protect the brain from Alzheimer’s damage. By turning off a circadian protein in mice, they raised NAD+ levels and reduced harmf...
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November 3, 2025 at 3:07 PM
Spirited experiments are brewing in the lab this Friday! 👻🧪

#GhostlyResearch #LabFun #rPeptide
October 31, 2025 at 4:15 PM
This highlights the development of a promising antibody therapy, #Amlenetug, designed to target toxic forms of Alpha-Synuclein

Our ASyn and ASyn 1-60 were used to characterize different conformations of the protein and select an antibody with the right binding properties

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#Research
Rational selection of the monoclonal α-synuclein antibody amlenetug (Lu AF82422) for the treatment of α-synucleinopathies - npj Parkinson's Disease
npj Parkinson's Disease - Rational selection of the monoclonal α-synuclein antibody amlenetug (Lu AF82422) for the treatment of α-synucleinopathies
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October 29, 2025 at 12:32 PM
Nature’s flash photography: 30,000°C in a blink! ⚡☀️

#FunFact #ScienceFun #rPeptide
October 27, 2025 at 2:52 PM
Our October Raffle Riddle winner is Aline! 🎉

Please check your email to claim your prize.

Thank you to everyone who participated!

#WinnerAnnouncement #rPeptide #Raffle #Prize
October 24, 2025 at 1:19 PM
We can’t see them, but atoms make up the world! ✨

#RaffleRiddle #ScienceFun #rPeptide
October 22, 2025 at 3:40 PM
Researchers found that Xanthohumol, a natural compound from hops, can destabilize harmful Amyloid-β oligomers and redirect them into larger, less toxic aggregates.

These findings shed light on how small molecules might shift the course of #Alzheimers by affecting protein aggregation.

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Xanthohumol destabilizes the structure of amyloid-β (Aβ) oligomers and promotes the formation of high-molecular-weight amorphous aggregates
This study provides a comprehensive structural analysis of prenylflavonoids (PFs) interaction with Aβ1–42 oligomers, revealing their potential to modu…
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October 20, 2025 at 2:28 PM
Music you can feel — literally! ✨

Researchers found that when we hear and feel music, our emotional response is amplified, sparking more joy and calm!

t.ly/dYYra

#Neuroscience #MusicTherapy #BrainHealth #rPeptide
Feeling the Music: Touch Amplifies Emotional Power of Sound - Neuroscience News
A new study shows that combining touch with hearing profoundly intensifies emotional responses to music.
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October 17, 2025 at 1:53 PM
Can you crack this one? The answer’s right in front of you… but unseen. 👀

#RaffleRiddle #ScienceFun #BrainTeaser #rPeptide
October 15, 2025 at 12:39 PM
A more standardized approach to detecting synucleinopathies like #Parkinsons Disease & #dementia with #LewyBodies.

A Universal Control Fluid was developed to improve consistency in ASyn RT-QuIC assays to detect misfolded proteins.

t.ly/Yq8oW

#Research #Development
Seeding amplification assay with Universal Control Fluid: Standardized detection of α-synucleinopathies
Seeding amplification assays, specifically the Real-Time Quaking-Induced Conversion method (RT-QuIC), have shown great diagnostic potential for α-synucleinopathies. Numerous research groups have demon...
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October 13, 2025 at 4:46 PM