Julian Rössler, MD
@roesslermd.bsky.social
Anesthesiologist @University Hospital Zurich, fellow @Outcomes Research Consortium & assistant editor @J-Clin-Anesth.bsky.social. Will do research for coffee!
As often evidence from regular medication use does not translate to perioperative single dose.
Revisit the February 2025 Infographic in Anesthesiology - Safe or Skip? Association Between Intraoperative Midazolam in Elderly Patients and Rates of Postop Delirium 🎨 ow.ly/Z7Tx50UH1jQ
July 30, 2025 at 6:59 AM
As often evidence from regular medication use does not translate to perioperative single dose.
Watch this interesting talk about gastric POCUS and GLP-1 agonists!
‼️New podcast‼️
@roesslermd.bsky.social interviews Dr. Christopher Wolla on preoperative ultrasound assessment of gastric volume in fasted surgical patients taking GLP-1 agonists.
📽️watch here: youtu.be/5ebe7frmR8I
🔗read the article: doi.org/10.1016/j.jclinane.2025.111853
#MedSky #AnSky
@roesslermd.bsky.social interviews Dr. Christopher Wolla on preoperative ultrasound assessment of gastric volume in fasted surgical patients taking GLP-1 agonists.
📽️watch here: youtu.be/5ebe7frmR8I
🔗read the article: doi.org/10.1016/j.jclinane.2025.111853
#MedSky #AnSky
July 30, 2025 at 6:53 AM
Watch this interesting talk about gastric POCUS and GLP-1 agonists!
‼️New podcast alert‼️
Our April podcast is here!
@roesslermd.bsky.social interviews Dr. A. Kaserer on his new trial on phosphate substitution in iron deficiency treatment with ferric carboxymaltose.
📽️watch here: youtu.be/UA-D6955LCY
🔗read the article: doi.org/10.1016/j.jclinane.2024.111727
#AnSky
Our April podcast is here!
@roesslermd.bsky.social interviews Dr. A. Kaserer on his new trial on phosphate substitution in iron deficiency treatment with ferric carboxymaltose.
📽️watch here: youtu.be/UA-D6955LCY
🔗read the article: doi.org/10.1016/j.jclinane.2024.111727
#AnSky
April 22, 2025 at 12:48 PM
Reposted by Julian Rössler, MD
‼️New podcast alert‼️
Our April podcast is here!
@roesslermd.bsky.social interviews Dr. A. Kaserer on his new trial on phosphate substitution in iron deficiency treatment with ferric carboxymaltose.
📽️watch here: youtu.be/UA-D6955LCY
🔗read the article: doi.org/10.1016/j.jclinane.2024.111727
#AnSky
Our April podcast is here!
@roesslermd.bsky.social interviews Dr. A. Kaserer on his new trial on phosphate substitution in iron deficiency treatment with ferric carboxymaltose.
📽️watch here: youtu.be/UA-D6955LCY
🔗read the article: doi.org/10.1016/j.jclinane.2024.111727
#AnSky
April 22, 2025 at 12:45 PM
‼️New podcast alert‼️
Our April podcast is here!
@roesslermd.bsky.social interviews Dr. A. Kaserer on his new trial on phosphate substitution in iron deficiency treatment with ferric carboxymaltose.
📽️watch here: youtu.be/UA-D6955LCY
🔗read the article: doi.org/10.1016/j.jclinane.2024.111727
#AnSky
Our April podcast is here!
@roesslermd.bsky.social interviews Dr. A. Kaserer on his new trial on phosphate substitution in iron deficiency treatment with ferric carboxymaltose.
📽️watch here: youtu.be/UA-D6955LCY
🔗read the article: doi.org/10.1016/j.jclinane.2024.111727
#AnSky
Reposted by Julian Rössler, MD
This retrospective analysis of 58,175 non-cardiac surgical procedures found that patients with chronic renal disease tend to improve kidney function after surgery - but only if they did not have AKI.
By @roesslermd.bsky.social
#MedSky #AnSky
🔗 doi.org/10.1016/j.jclinane.2025.111745
By @roesslermd.bsky.social
#MedSky #AnSky
🔗 doi.org/10.1016/j.jclinane.2025.111745
March 16, 2025 at 9:56 AM
This retrospective analysis of 58,175 non-cardiac surgical procedures found that patients with chronic renal disease tend to improve kidney function after surgery - but only if they did not have AKI.
By @roesslermd.bsky.social
#MedSky #AnSky
🔗 doi.org/10.1016/j.jclinane.2025.111745
By @roesslermd.bsky.social
#MedSky #AnSky
🔗 doi.org/10.1016/j.jclinane.2025.111745
Reposted by Julian Rössler, MD
‼️New podcast alert‼️
Our January 2025 podcast is here!
Dr. Moore interviews Dr. Saugel on his recent pilot trial on personalized perioperative blood pressure management.
📽️watch here: youtu.be/OU_WtQYEVI4?si=fixRAY7plz9MfXdB
🔗read the article: doi.org/10.1016/j.jclinane.2024.111687
#AnSky #MedSky
Our January 2025 podcast is here!
Dr. Moore interviews Dr. Saugel on his recent pilot trial on personalized perioperative blood pressure management.
📽️watch here: youtu.be/OU_WtQYEVI4?si=fixRAY7plz9MfXdB
🔗read the article: doi.org/10.1016/j.jclinane.2024.111687
#AnSky #MedSky
February 14, 2025 at 1:53 PM
‼️New podcast alert‼️
Our January 2025 podcast is here!
Dr. Moore interviews Dr. Saugel on his recent pilot trial on personalized perioperative blood pressure management.
📽️watch here: youtu.be/OU_WtQYEVI4?si=fixRAY7plz9MfXdB
🔗read the article: doi.org/10.1016/j.jclinane.2024.111687
#AnSky #MedSky
Our January 2025 podcast is here!
Dr. Moore interviews Dr. Saugel on his recent pilot trial on personalized perioperative blood pressure management.
📽️watch here: youtu.be/OU_WtQYEVI4?si=fixRAY7plz9MfXdB
🔗read the article: doi.org/10.1016/j.jclinane.2024.111687
#AnSky #MedSky
Reposted by Julian Rössler, MD
Personalized perioperative blood pressure management in patients having major non-cardiac surgery: A bicentric pilot randomized trial
➡️ Preoperative automated blood pressure monitoring & targeting nighttime MAP during surgery is feasible.
#AnSky #MedSky
🔗 doi.org/10.1016/j.jclinane.2024.111687
➡️ Preoperative automated blood pressure monitoring & targeting nighttime MAP during surgery is feasible.
#AnSky #MedSky
🔗 doi.org/10.1016/j.jclinane.2024.111687
January 31, 2025 at 8:05 AM
Personalized perioperative blood pressure management in patients having major non-cardiac surgery: A bicentric pilot randomized trial
➡️ Preoperative automated blood pressure monitoring & targeting nighttime MAP during surgery is feasible.
#AnSky #MedSky
🔗 doi.org/10.1016/j.jclinane.2024.111687
➡️ Preoperative automated blood pressure monitoring & targeting nighttime MAP during surgery is feasible.
#AnSky #MedSky
🔗 doi.org/10.1016/j.jclinane.2024.111687
Can having surgery affect progression of chronic kidney disease?
Our new retrospective analysis of 58,175 non-cardiac surgeries, found that having surgery was associated with improved kidney function in patients with CKD - but only if there was no AKI.
🔗 doi.org/10.1016/j.jclinane.2025.111745
Our new retrospective analysis of 58,175 non-cardiac surgeries, found that having surgery was associated with improved kidney function in patients with CKD - but only if there was no AKI.
🔗 doi.org/10.1016/j.jclinane.2025.111745
January 16, 2025 at 5:34 PM
Can having surgery affect progression of chronic kidney disease?
Our new retrospective analysis of 58,175 non-cardiac surgeries, found that having surgery was associated with improved kidney function in patients with CKD - but only if there was no AKI.
🔗 doi.org/10.1016/j.jclinane.2025.111745
Our new retrospective analysis of 58,175 non-cardiac surgeries, found that having surgery was associated with improved kidney function in patients with CKD - but only if there was no AKI.
🔗 doi.org/10.1016/j.jclinane.2025.111745
Reposted by Julian Rössler, MD
VVZ-149 is a novel, non-opioid, non-NSAID analgesic drug: It inhibits type 2 glycine transporter and type 2A serotonin receptor.
In this phase 3 trial, VVZ-149 showed a significant reduction of pain and opioid use within the first 12h after surgery.
🔗 doi.org/10.1016/j.jclinane.2024.111729
🔗 doi.org/10.1016/j.jclinane.2024.111729
January 16, 2025 at 5:20 AM
VVZ-149 is a novel, non-opioid, non-NSAID analgesic drug: It inhibits type 2 glycine transporter and type 2A serotonin receptor.
In this phase 3 trial, VVZ-149 showed a significant reduction of pain and opioid use within the first 12h after surgery.
🔗 doi.org/10.1016/j.jclinane.2024.111729
🔗 doi.org/10.1016/j.jclinane.2024.111729
Reposted by Julian Rössler, MD
Since 1978, Dr. Michael Pinsky's scientific career has revolved around the clinical significance of heart-lung interactions. Read the Classic Papers Revisited article outlining his critical contributions to the field: ow.ly/BR5j50UC0fT
January 9, 2025 at 6:27 PM
Since 1978, Dr. Michael Pinsky's scientific career has revolved around the clinical significance of heart-lung interactions. Read the Classic Papers Revisited article outlining his critical contributions to the field: ow.ly/BR5j50UC0fT
Reposted by Julian Rössler, MD
Evidence into practice!
Adequate TOF monitoring is still not ubiquitous. This large interrupted time series & quality improvement project shows successful large-scale integration of quantitative TOF monitoring and evidence based NMB management.
🔗 doi.org/10.1016/j.jclinane.2024.111709
Adequate TOF monitoring is still not ubiquitous. This large interrupted time series & quality improvement project shows successful large-scale integration of quantitative TOF monitoring and evidence based NMB management.
🔗 doi.org/10.1016/j.jclinane.2024.111709
January 11, 2025 at 7:19 AM
Evidence into practice!
Adequate TOF monitoring is still not ubiquitous. This large interrupted time series & quality improvement project shows successful large-scale integration of quantitative TOF monitoring and evidence based NMB management.
🔗 doi.org/10.1016/j.jclinane.2024.111709
Adequate TOF monitoring is still not ubiquitous. This large interrupted time series & quality improvement project shows successful large-scale integration of quantitative TOF monitoring and evidence based NMB management.
🔗 doi.org/10.1016/j.jclinane.2024.111709
Rate my setup.
December 22, 2024 at 1:28 PM
Rate my setup.
Somebody let my neurosurgeons know please!
Severe PPCs were more common in the ‘low etCO₂’ group (35 % vs. 18 %). Propensity score matching did not alter the results, showing a robust association.
December 20, 2024 at 10:27 PM
Somebody let my neurosurgeons know please!
Reposted by Julian Rössler, MD
No significant difference was found in overall PPCs between ‘low etCO₂ (below 35 mmHg)’ and ‘normal to high etCO₂ (≥ 35 mmHg)’ patients (20 % vs. 19 %).
December 20, 2024 at 7:58 PM
No significant difference was found in overall PPCs between ‘low etCO₂ (below 35 mmHg)’ and ‘normal to high etCO₂ (≥ 35 mmHg)’ patients (20 % vs. 19 %).
Reposted by Julian Rössler, MD
This secondary analysis of the LAS VEGAS observational study aimed to examine the association between etCO₂ levels and the occurrence of postoperative pulmonary complications (PCCs).
By the PROVE network.
#AnSky #MedSky
🔗 doi.org/10.1016/j.jclinane.2024.111728
By the PROVE network.
#AnSky #MedSky
🔗 doi.org/10.1016/j.jclinane.2024.111728
December 20, 2024 at 7:58 PM
This secondary analysis of the LAS VEGAS observational study aimed to examine the association between etCO₂ levels and the occurrence of postoperative pulmonary complications (PCCs).
By the PROVE network.
#AnSky #MedSky
🔗 doi.org/10.1016/j.jclinane.2024.111728
By the PROVE network.
#AnSky #MedSky
🔗 doi.org/10.1016/j.jclinane.2024.111728
Reposted by Julian Rössler, MD
Possible alternative to paravertebral blocks?
➡️Intertransverse process blocks at the retro-superior costotransverse ligament space
This study evaluated local anesthetic spread using MRI and sensory block in healthy volunteers.
#RASky #AnSky #MedSky
🔗 doi.org/10.1016/j.jclinane.2024.111718
➡️Intertransverse process blocks at the retro-superior costotransverse ligament space
This study evaluated local anesthetic spread using MRI and sensory block in healthy volunteers.
#RASky #AnSky #MedSky
🔗 doi.org/10.1016/j.jclinane.2024.111718
December 18, 2024 at 6:53 PM
Possible alternative to paravertebral blocks?
➡️Intertransverse process blocks at the retro-superior costotransverse ligament space
This study evaluated local anesthetic spread using MRI and sensory block in healthy volunteers.
#RASky #AnSky #MedSky
🔗 doi.org/10.1016/j.jclinane.2024.111718
➡️Intertransverse process blocks at the retro-superior costotransverse ligament space
This study evaluated local anesthetic spread using MRI and sensory block in healthy volunteers.
#RASky #AnSky #MedSky
🔗 doi.org/10.1016/j.jclinane.2024.111718
Reposted by Julian Rössler, MD
Mitochondrial oxygenation monitoring and acute kidney injury risk in cardiac surgery: A prospective cohort study
Read this article & more from our February issue!
🔗 doi.org/10.1016/j.jclinane.2024.111715
Read this article & more from our February issue!
🔗 doi.org/10.1016/j.jclinane.2024.111715
December 15, 2024 at 8:42 PM
Mitochondrial oxygenation monitoring and acute kidney injury risk in cardiac surgery: A prospective cohort study
Read this article & more from our February issue!
🔗 doi.org/10.1016/j.jclinane.2024.111715
Read this article & more from our February issue!
🔗 doi.org/10.1016/j.jclinane.2024.111715
Did you know that ferric carboxymaltose can cause hypophosphatemia?
In the DeFicit trial we evaluated if this could be mitigated by oral phosphate supplementation.
#PatientBloodManagement
In the DeFicit trial we evaluated if this could be mitigated by oral phosphate supplementation.
#PatientBloodManagement
The DeFicit #RCT found that oral phosphate supplementation for 30 days after ferric carboxymaltose administration did not affect mean lowest phosphate levels, but reduced the incidence of hypophosphatemia.
@roesslermd.bsky.social et al.
#PBM #MedSky #AnSky
🔗 doi.org/10.1016/j.jclinane.2024.111727
@roesslermd.bsky.social et al.
#PBM #MedSky #AnSky
🔗 doi.org/10.1016/j.jclinane.2024.111727
December 13, 2024 at 1:44 PM
Did you know that ferric carboxymaltose can cause hypophosphatemia?
In the DeFicit trial we evaluated if this could be mitigated by oral phosphate supplementation.
#PatientBloodManagement
In the DeFicit trial we evaluated if this could be mitigated by oral phosphate supplementation.
#PatientBloodManagement
Could Aspirin also be promising for MINS?
POISE-2 would say no, but what about in a cohort of patients with confirmed MINS?
POISE-2 would say no, but what about in a cohort of patients with confirmed MINS?
#Sepsis induced myocardial injury (SIMI) has a high mortality rate, and effective treatment strategies are limited.
This analysis of the MIMIC-IV database reported that aspirin use was associated with reduced mortality in patients with SIMI.
#MedSky #AnSky
🔗 doi.org/10.1016/j.jclinane.2024.111597
This analysis of the MIMIC-IV database reported that aspirin use was associated with reduced mortality in patients with SIMI.
#MedSky #AnSky
🔗 doi.org/10.1016/j.jclinane.2024.111597
December 11, 2024 at 3:47 PM
Could Aspirin also be promising for MINS?
POISE-2 would say no, but what about in a cohort of patients with confirmed MINS?
POISE-2 would say no, but what about in a cohort of patients with confirmed MINS?
This study was a massive team effort! Huge thanks to everybody.
Read this thread on our latest publication, the COSMOS study:
Read this thread on our latest publication, the COSMOS study:
Just published!
Results from the COSMOS pilot:
COSMOS is a two-part prospective observational study & randomized trial in 250 patients, all of whom had continuous ward respiratory monitoring for 48 postoperative hours.
🧵 A thread!
Results from the COSMOS pilot:
COSMOS is a two-part prospective observational study & randomized trial in 250 patients, all of whom had continuous ward respiratory monitoring for 48 postoperative hours.
🧵 A thread!
December 10, 2024 at 5:11 PM
This study was a massive team effort! Huge thanks to everybody.
Read this thread on our latest publication, the COSMOS study:
Read this thread on our latest publication, the COSMOS study:
How many intubations are needed to master the use of a hyperangulated blade? Explore and find out:
Thanks to the whole team for making this amazing study happen!
Thanks to the whole team for making this amazing study happen!
Clinicians with previous experience in direct laryngoscopy required an average of 12 tracheal intubation attempts with hyperangulated videolaryngoscopy to achieve an acceptable first-attempt tracheal intubation success rate.
#AnSky #MedSky #AirwaySky
https://buff.ly/3CVoXIZ
#AnSky #MedSky #AirwaySky
https://buff.ly/3CVoXIZ
December 9, 2024 at 9:28 PM
How many intubations are needed to master the use of a hyperangulated blade? Explore and find out:
Thanks to the whole team for making this amazing study happen!
Thanks to the whole team for making this amazing study happen!
Happy to be part of the @j-clin-anesth.bsky.social social media editorial team!
The Journal of Clinical Anesthesia is joining the 🦋 #anesthesiology community!
Hello to our friends at @anaesjournal.bsky.social, @bjajournals.bsky.social, @anesthesiology.bsky.social, @iarsjournals.bsky.social.
Excited to be here!
Hello to our friends at @anaesjournal.bsky.social, @bjajournals.bsky.social, @anesthesiology.bsky.social, @iarsjournals.bsky.social.
Excited to be here!
December 9, 2024 at 9:22 PM
Happy to be part of the @j-clin-anesth.bsky.social social media editorial team!