@quadrapole.bsky.social
SBIR/STTR News
Here is a good summary from where things stand. Sen. Ernst is preventing the clear 1-yr extension from going through. Instead, she is pushing for her Innovate ACT, which would limit PIs to only one and orgs. to only 3 application per solicitation per year.
jm-aq.com/innovation-s...
Here is a good summary from where things stand. Sen. Ernst is preventing the clear 1-yr extension from going through. Instead, she is pushing for her Innovate ACT, which would limit PIs to only one and orgs. to only 3 application per solicitation per year.
jm-aq.com/innovation-s...
Innovation Stalled: The Fight Over SBIR/STTR Reauthorization
SBIR/STTR funding is frozen as Congress debates reauthorization. Learn about competing bills, proposed reforms, and what’s next
jm-aq.com
November 25, 2025 at 6:01 PM
SBIR/STTR News
Here is a good summary from where things stand. Sen. Ernst is preventing the clear 1-yr extension from going through. Instead, she is pushing for her Innovate ACT, which would limit PIs to only one and orgs. to only 3 application per solicitation per year.
jm-aq.com/innovation-s...
Here is a good summary from where things stand. Sen. Ernst is preventing the clear 1-yr extension from going through. Instead, she is pushing for her Innovate ACT, which would limit PIs to only one and orgs. to only 3 application per solicitation per year.
jm-aq.com/innovation-s...
NIH Grant Update -
"All grant applications submitted late for due dates between October 1, 2025, and December 5, 2025, will be accepted through 5:00 PM local time December 8, 2025."
grants.nih.gov/grants/guide...
"All grant applications submitted late for due dates between October 1, 2025, and December 5, 2025, will be accepted through 5:00 PM local time December 8, 2025."
grants.nih.gov/grants/guide...
NOT-OD-26-012: Updated Guidance on Reopening of NIH Extramural Activities Following the October 1, 2025 - Lapse in Appropriations
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Updated Guidance on Reopening of NIH Extramural Activities Following the October 1, 2025 - Lapse in Appropriations NOT-...
grants.nih.gov
November 24, 2025 at 6:16 PM
NIH Grant Update -
"All grant applications submitted late for due dates between October 1, 2025, and December 5, 2025, will be accepted through 5:00 PM local time December 8, 2025."
grants.nih.gov/grants/guide...
"All grant applications submitted late for due dates between October 1, 2025, and December 5, 2025, will be accepted through 5:00 PM local time December 8, 2025."
grants.nih.gov/grants/guide...
NIH SBIR/STTR update
Sen. Ernst is trying to attach her SBIR Innovate proposal to the NDAA reauthorization. It seems like a longshot given that some of the changes are substantial and Congress has not reviewed it. I suspect the clean 1-yr extension will go in.
punchbowl.news/article/defe...
Sen. Ernst is trying to attach her SBIR Innovate proposal to the NDAA reauthorization. It seems like a longshot given that some of the changes are substantial and Congress has not reviewed it. I suspect the clean 1-yr extension will go in.
punchbowl.news/article/defe...
Ernst eyes NDAA for small biz push
News: Sen. Joni Ernst (R-Iowa) is working to shoehorn her plan to renew two small business grant programs into the annual defense policy bill.
punchbowl.news
November 24, 2025 at 2:40 PM
NIH SBIR/STTR update
Sen. Ernst is trying to attach her SBIR Innovate proposal to the NDAA reauthorization. It seems like a longshot given that some of the changes are substantial and Congress has not reviewed it. I suspect the clean 1-yr extension will go in.
punchbowl.news/article/defe...
Sen. Ernst is trying to attach her SBIR Innovate proposal to the NDAA reauthorization. It seems like a longshot given that some of the changes are substantial and Congress has not reviewed it. I suspect the clean 1-yr extension will go in.
punchbowl.news/article/defe...
NIH SBIR/STTR Update
From what I can tell, nearly all SRG meeting in November and December have been pushed into January. At least they're happening at all after the shutdown.
From what I can tell, nearly all SRG meeting in November and December have been pushed into January. At least they're happening at all after the shutdown.
November 24, 2025 at 2:36 PM
NIH SBIR/STTR Update
From what I can tell, nearly all SRG meeting in November and December have been pushed into January. At least they're happening at all after the shutdown.
From what I can tell, nearly all SRG meeting in November and December have been pushed into January. At least they're happening at all after the shutdown.
SBIR/STTR Update
The best hope is that the SBIR/STTR reauthorization is attached to the NDAA, due to be voted on in a few weeks. The clean 1-year extension would hopefully be the most "agreeable" mechanism. Stay tuned.
The best hope is that the SBIR/STTR reauthorization is attached to the NDAA, due to be voted on in a few weeks. The clean 1-year extension would hopefully be the most "agreeable" mechanism. Stay tuned.
November 21, 2025 at 3:04 PM
SBIR/STTR Update
The best hope is that the SBIR/STTR reauthorization is attached to the NDAA, due to be voted on in a few weeks. The clean 1-year extension would hopefully be the most "agreeable" mechanism. Stay tuned.
The best hope is that the SBIR/STTR reauthorization is attached to the NDAA, due to be voted on in a few weeks. The clean 1-year extension would hopefully be the most "agreeable" mechanism. Stay tuned.
Several NIH opportunities are being forcibly retired.
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
NOT-AG-25-023: Notice of Early Expiration of PAR-25-331, "Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R21 Clinical Trial Optional)"
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Early Expiration of PAR-25-331,
grants.nih.gov
November 20, 2025 at 7:09 PM
Several NIH opportunities are being forcibly retired.
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
Updated Terms and Conditions of Award – Termination and Compliance with Court Orders
In short, the language makes it easier for award termination.
grants.nih.gov/grants/guide...
In short, the language makes it easier for award termination.
grants.nih.gov/grants/guide...
NOT-OD-26-009: Updated Terms and Conditions of Award Termination and Compliance with Court Orders
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Updated Terms and Conditions of Award Termination and Compliance with Court Orders NOT-OD-26-009. NIH
grants.nih.gov
November 18, 2025 at 8:56 PM
Updated Terms and Conditions of Award – Termination and Compliance with Court Orders
In short, the language makes it easier for award termination.
grants.nih.gov/grants/guide...
In short, the language makes it easier for award termination.
grants.nih.gov/grants/guide...
NIH cuts impacted 74,000 clinical trial patients: study
www.axios.com/2025/11/18/n...
www.axios.com/2025/11/18/n...
NIH cuts impacted 74,000 clinical trial patients: study
The termination of federal research grants disrupted about 1 in 30 NIH-funded clinical trials.
www.axios.com
November 18, 2025 at 3:09 PM
NIH cuts impacted 74,000 clinical trial patients: study
www.axios.com/2025/11/18/n...
www.axios.com/2025/11/18/n...
FYI - Notice of Early Expiration of NIH Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Notices of Funding Opportunity and Guidance for Existing Recipients (NOT-OD-26-006)
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
NOT-OD-26-006: Notice of Early Expiration of NIH Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Notices of Funding Opportunity and Guidance for Existing Recipi...
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Early Expiration of NIH Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STT...
grants.nih.gov
November 17, 2025 at 8:18 PM
FYI - Notice of Early Expiration of NIH Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Notices of Funding Opportunity and Guidance for Existing Recipients (NOT-OD-26-006)
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
NIH grant peer review
Per NOT-OD-26-004, peer review is on hold during the shutdown. NIH SBIR/STTR proposal reviews were due to start already. Hopefully, NIH staff will find a solution 🙏. Given that the SBIR/STTR program has not been reauthorized, this could be the last submission cycle... Ever.
Per NOT-OD-26-004, peer review is on hold during the shutdown. NIH SBIR/STTR proposal reviews were due to start already. Hopefully, NIH staff will find a solution 🙏. Given that the SBIR/STTR program has not been reauthorized, this could be the last submission cycle... Ever.
November 12, 2025 at 6:29 PM
NIH grant peer review
Per NOT-OD-26-004, peer review is on hold during the shutdown. NIH SBIR/STTR proposal reviews were due to start already. Hopefully, NIH staff will find a solution 🙏. Given that the SBIR/STTR program has not been reauthorized, this could be the last submission cycle... Ever.
Per NOT-OD-26-004, peer review is on hold during the shutdown. NIH SBIR/STTR proposal reviews were due to start already. Hopefully, NIH staff will find a solution 🙏. Given that the SBIR/STTR program has not been reauthorized, this could be the last submission cycle... Ever.
Reposted
NIH will no longer list NIH grant opportunities through the NIH Guide.
Sure, grants.gov was duplicative. But grants.gov is shitty. And NIH's Guide was less shitty.
Not a huge deal. But just one more example of exec branch consolidation and NIH enshittification
grants.nih.gov/grants/guide...
Sure, grants.gov was duplicative. But grants.gov is shitty. And NIH's Guide was less shitty.
Not a huge deal. But just one more example of exec branch consolidation and NIH enshittification
grants.nih.gov/grants/guide...
August 15, 2025 at 1:50 PM
NIH will no longer list NIH grant opportunities through the NIH Guide.
Sure, grants.gov was duplicative. But grants.gov is shitty. And NIH's Guide was less shitty.
Not a huge deal. But just one more example of exec branch consolidation and NIH enshittification
grants.nih.gov/grants/guide...
Sure, grants.gov was duplicative. But grants.gov is shitty. And NIH's Guide was less shitty.
Not a huge deal. But just one more example of exec branch consolidation and NIH enshittification
grants.nih.gov/grants/guide...
Notice of Early Termination of PAR-24-258: Research Resource for Human Organs and Tissues
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
NOT-OD-25-144: Notice of Early Termination of PAR-24-258: Research Resource for Human Organs and Tissues (U42 Clinical Trial Not Allowed)
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Early Termination of PAR-24-258: Research Resource for Human Organs and Tissues (U42 Clinical Trial Not Allow...
grants.nih.gov
August 8, 2025 at 2:47 PM
Notice of Early Termination of PAR-24-258: Research Resource for Human Organs and Tissues
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
Good news from the NIH. Recipients may resume initiating first no-cost extensions in eRA Commons.
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
NOT-OD-25-142: Update: No-Cost Extension Functionality in eRA
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Update: No-Cost Extension Functionality in eRA NOT-OD-25-142. NIH
grants.nih.gov
August 7, 2025 at 6:41 PM
Good news from the NIH. Recipients may resume initiating first no-cost extensions in eRA Commons.
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
Reposted
🧪 Senate appropriators say: NIH's budget gets a... boost!
Rather than 40% cut, NIH gets a $400M *increase* in the Senate committee bill for FY26 (about +1%).
"Congress has your back," said @murray.senate.gov.
ADVOCACY MATTERS! There's still a long road (esp in the House), so keep up pressure.
Rather than 40% cut, NIH gets a $400M *increase* in the Senate committee bill for FY26 (about +1%).
"Congress has your back," said @murray.senate.gov.
ADVOCACY MATTERS! There's still a long road (esp in the House), so keep up pressure.
Full Committee Markup of Defense and Labor, Health and Human Services, and Education Appropriations Acts | United States Senate Committee on Appropriations
United States Senate Committee on Appropriations
www.appropriations.senate.gov
July 31, 2025 at 1:54 PM
🧪 Senate appropriators say: NIH's budget gets a... boost!
Rather than 40% cut, NIH gets a $400M *increase* in the Senate committee bill for FY26 (about +1%).
"Congress has your back," said @murray.senate.gov.
ADVOCACY MATTERS! There's still a long road (esp in the House), so keep up pressure.
Rather than 40% cut, NIH gets a $400M *increase* in the Senate committee bill for FY26 (about +1%).
"Congress has your back," said @murray.senate.gov.
ADVOCACY MATTERS! There's still a long road (esp in the House), so keep up pressure.
Reposted
My quote of the day
Ignorance is not bad faith. But persistence in ignorance is.
Joanna Russ
Ignorance is not bad faith. But persistence in ignorance is.
Joanna Russ
July 30, 2025 at 11:31 AM
My quote of the day
Ignorance is not bad faith. But persistence in ignorance is.
Joanna Russ
Ignorance is not bad faith. But persistence in ignorance is.
Joanna Russ
Reposted
Hell yeah, keep the pressure on.
If you live in one of these states, call your Senators, thank them, and remind them that there are related issues where their states and the nation needs their support and willingness to stand up.
If you live in one of these states, call your Senators, thank them, and remind them that there are related issues where their states and the nation needs their support and willingness to stand up.
July 29, 2025 at 12:40 PM
Hell yeah, keep the pressure on.
If you live in one of these states, call your Senators, thank them, and remind them that there are related issues where their states and the nation needs their support and willingness to stand up.
If you live in one of these states, call your Senators, thank them, and remind them that there are related issues where their states and the nation needs their support and willingness to stand up.
Reposted
Another new #NIH Notice published today. In addition to the AI information referenced below, NIH is also instituting a new policy limiting the number of applications that NIH will consider per Principal Investigator per calendar year. It's included in this Notice. #RAdminsky #Research #Medsky
NIH issues new policy stating that it will not consider research grant applications “substantially developed” by AI to be original ideas of the applicant.
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
NOT-OD-25-132: Supporting Fairness and Originality in NIH Research Applications
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supporting Fairness and Originality in NIH Research Applications NOT-OD-25-132. NIH
grants.nih.gov
July 17, 2025 at 4:45 PM
Another new #NIH Notice published today. In addition to the AI information referenced below, NIH is also instituting a new policy limiting the number of applications that NIH will consider per Principal Investigator per calendar year. It's included in this Notice. #RAdminsky #Research #Medsky
As I feared, more NIH SBIR/STTR grants are pulled due to BS "foreign affiliations".
St. Louis biomed firm was on the cusp of a breakthrough TB drug. Then its funding was cut.
Fimbrion Therapeutics was blindsided by an abrupt and unexplained cut in National Institutes of Health funding.
St. Louis biomed firm was on the cusp of a breakthrough TB drug. Then its funding was cut.
Fimbrion Therapeutics was blindsided by an abrupt and unexplained cut in National Institutes of Health funding.
St. Louis biomed firm was on the cusp of a breakthrough TB drug. Then its funding was cut.
Fimbrion Therapeutics was blindsided by an abrupt and unexplained cut in National Institutes of Health funding. Not only is its research jeopardized, the company may close.
www.stltoday.com
June 23, 2025 at 5:44 PM
As I feared, more NIH SBIR/STTR grants are pulled due to BS "foreign affiliations".
St. Louis biomed firm was on the cusp of a breakthrough TB drug. Then its funding was cut.
Fimbrion Therapeutics was blindsided by an abrupt and unexplained cut in National Institutes of Health funding.
St. Louis biomed firm was on the cusp of a breakthrough TB drug. Then its funding was cut.
Fimbrion Therapeutics was blindsided by an abrupt and unexplained cut in National Institutes of Health funding.
This is interesting.
RESCINDED - Notice of Civil Rights Term and Condition of Award (NOT-OD-25-090)
The original directive (issued on 4/21/2025) stating that entities must not have DEI, DEIA, etc. in order to receive a federal grant was rescinded today.
grants.nih.gov/grants/guide...
RESCINDED - Notice of Civil Rights Term and Condition of Award (NOT-OD-25-090)
The original directive (issued on 4/21/2025) stating that entities must not have DEI, DEIA, etc. in order to receive a federal grant was rescinded today.
grants.nih.gov/grants/guide...
NOT-OD-25-124: Notice of Rescission of Civil Rights Term and Condition of Award
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Rescission of Civil Rights Term and Condition of Award NOT-OD-25-124. NIH
grants.nih.gov
June 9, 2025 at 1:55 PM
This is interesting.
RESCINDED - Notice of Civil Rights Term and Condition of Award (NOT-OD-25-090)
The original directive (issued on 4/21/2025) stating that entities must not have DEI, DEIA, etc. in order to receive a federal grant was rescinded today.
grants.nih.gov/grants/guide...
RESCINDED - Notice of Civil Rights Term and Condition of Award (NOT-OD-25-090)
The original directive (issued on 4/21/2025) stating that entities must not have DEI, DEIA, etc. in order to receive a federal grant was rescinded today.
grants.nih.gov/grants/guide...
Well, the NIH FINALLY released a new RFA -
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
RFA-FD-25-024: A Research Study of Contaminants in School Meals (U18)
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: A Research Study of Contaminants in School Meals (U18) RFA-FD-25-024. FDA
grants.nih.gov
June 6, 2025 at 6:15 PM
Well, the NIH FINALLY released a new RFA -
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
NIH Update: No more prior approval for no-cost extensions
No-cost extensions must now be requested after the project end date, not before—making funding continuity harder and giving DODGE more leverage to block or delay extensions for projects it deprioritizes.
No-cost extensions must now be requested after the project end date, not before—making funding continuity harder and giving DODGE more leverage to block or delay extensions for projects it deprioritizes.
May 22, 2025 at 2:31 PM
NIH Update: No more prior approval for no-cost extensions
No-cost extensions must now be requested after the project end date, not before—making funding continuity harder and giving DODGE more leverage to block or delay extensions for projects it deprioritizes.
No-cost extensions must now be requested after the project end date, not before—making funding continuity harder and giving DODGE more leverage to block or delay extensions for projects it deprioritizes.
Looks like the NIBIB is winding down too -
Note the following - "Effective immediately, the final receipt date for this NOFO (RFA-EB-22-002) has been canceled. No further applications will be accepted for consideration under this NOFO."
grants.nih.gov/grants/guide...
Note the following - "Effective immediately, the final receipt date for this NOFO (RFA-EB-22-002) has been canceled. No further applications will be accepted for consideration under this NOFO."
grants.nih.gov/grants/guide...
NOT-EB-25-001: Notice of Early Expiration of RFA-EB-22-002, "HEAL Initiative: Translational Development of Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed)"
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Early Expiration of RFA-EB-22-002,
grants.nih.gov
April 16, 2025 at 6:46 PM
Looks like the NIBIB is winding down too -
Note the following - "Effective immediately, the final receipt date for this NOFO (RFA-EB-22-002) has been canceled. No further applications will be accepted for consideration under this NOFO."
grants.nih.gov/grants/guide...
Note the following - "Effective immediately, the final receipt date for this NOFO (RFA-EB-22-002) has been canceled. No further applications will be accepted for consideration under this NOFO."
grants.nih.gov/grants/guide...