Nat Trigg
@natrigg.bsky.social
Postdoc @ University of Newcastle Australia | Male reproductive biology
Reposted by Nat Trigg
Male mice exposed to PFAS (an environmental contaminant) have reduced sperm production but normal sperm viability & motility. Embryos created by IVF with PFAS-treated sperm have disrupted transcriptomes suggesting possible transgenerational effects.
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Exposure of mice to environmentally relevant per- and polyfluoroalkyl substances (PFAS) alters the sperm epigenome - Communications Biology
Male mice exposed to PFAS (a group of environmental contaminants) have reduced sperm production but normal sperm viability & motility. Embryos created by in vitro fertilisation (IVF) with PFA...
www.nature.com
November 4, 2025 at 7:13 PM
Male mice exposed to PFAS (an environmental contaminant) have reduced sperm production but normal sperm viability & motility. Embryos created by IVF with PFAS-treated sperm have disrupted transcriptomes suggesting possible transgenerational effects.
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Reposted by Nat Trigg
Check out our (@natrigg.bsky.social and Grace Lee) protocol for determining the functions of sperm, and other, RNAs during early development. star-protocols.cell.com/protocols/4200
Cell Press: STAR Protocols
STAR Protocols is an open access, peer-reviewed journal from Cell Press. We offer structured, transparent, accessible, and repeatable step-by-step experimental and computational protocols from all are...
star-protocols.cell.com
May 11, 2025 at 11:39 AM
Check out our (@natrigg.bsky.social and Grace Lee) protocol for determining the functions of sperm, and other, RNAs during early development. star-protocols.cell.com/protocols/4200
Reposted by Nat Trigg
🚨 New Resource for Reproductive Researchers! 🧪🔬
Are you exploring sperm biology, male infertility, or contraceptive development?
📢 We’ve just released a comprehensive step-by-step guide (preprint) to generate and analyse human sperm phosphoproteomes; a crucial but underexplored area.
Are you exploring sperm biology, male infertility, or contraceptive development?
📢 We’ve just released a comprehensive step-by-step guide (preprint) to generate and analyse human sperm phosphoproteomes; a crucial but underexplored area.
osf.io
March 31, 2025 at 1:57 PM
🚨 New Resource for Reproductive Researchers! 🧪🔬
Are you exploring sperm biology, male infertility, or contraceptive development?
📢 We’ve just released a comprehensive step-by-step guide (preprint) to generate and analyse human sperm phosphoproteomes; a crucial but underexplored area.
Are you exploring sperm biology, male infertility, or contraceptive development?
📢 We’ve just released a comprehensive step-by-step guide (preprint) to generate and analyse human sperm phosphoproteomes; a crucial but underexplored area.
JCI Insight - In Vitro Fertilization induces reproductive changes in male mouse offspring and has multigenerational effects insight.jci.org/articles/vie...
JCI Insight -
In Vitro Fertilization induces reproductive changes in male mouse offspring and has multigenerational effects
insight.jci.org
March 4, 2025 at 10:45 PM
JCI Insight - In Vitro Fertilization induces reproductive changes in male mouse offspring and has multigenerational effects insight.jci.org/articles/vie...
Working with germ-free mice with the Kambayashi Lab we saw a 'swollen' epididymal phenotype occurring, so we took a closer look doi.org/10.1530/REP-...
A lack of commensal microbiota influences the male reproductive tract intergenerationally in mice
The microbiome encompasses the array of microorganisms inhabiting various niches in the body and is necessary for numerous physiological processes, including normal metabolism and a functioning immune...
doi.org
February 16, 2025 at 5:01 AM
Working with germ-free mice with the Kambayashi Lab we saw a 'swollen' epididymal phenotype occurring, so we took a closer look doi.org/10.1530/REP-...
Reposted by Nat Trigg
Australia is known for its hot conditions, but new findings from HMRI's Infertility and Reproduction research program have found that heatwave conditions can impact the health of sperm. Learn more hmri.org.au/news-and-sto...
January 21, 2025 at 3:09 AM
Australia is known for its hot conditions, but new findings from HMRI's Infertility and Reproduction research program have found that heatwave conditions can impact the health of sperm. Learn more hmri.org.au/news-and-sto...
Reposted by Nat Trigg
Happy to have contributed to this led by the Nixon lab. We helped show temperarure can alter sperm small RNAs which modulate postfertiilzation embryonic gene expression and development in 🐁
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
www.pnas.org
November 23, 2024 at 12:28 PM
Happy to have contributed to this led by the Nixon lab. We helped show temperarure can alter sperm small RNAs which modulate postfertiilzation embryonic gene expression and development in 🐁
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...