Mary Schulz
@maryschulz.bsky.social
PhD Candidate in @jcastorena.bsky.social Castorena Lab at Tulane BMS
Pinned
Mary Schulz
@maryschulz.bsky.social
· Jun 2
Regulation of Collecting Lymphatic Vessel Contractile Function by TRPV4 Channels | Arteriosclerosis, Thrombosis, and Vascular Biology
BACKGROUND: Dysregulation of TRPV4 (transient receptor potential vanilloid type 4)–mediated signaling
has been associated with inflammation and tissue fibrosis, both of which are key features
in the p...
www.ahajournals.org
Excited to share our work on TRPV4 channels in lymphatic contractile function! www.ahajournals.org/doi/10.1161/...
@jcastorena.bsky.social
@ahajournals.bsky.social
@ahascience.bsky.social
@jcastorena.bsky.social
@ahajournals.bsky.social
@ahascience.bsky.social
Reposted by Mary Schulz
Very proud of my student @maryschulz.bsky.social, who just received a NOA for her NIH-F31 project to study obesity-induced lymphatic dysfunction and explore novel therapeutics. Also, her recent paper (www.ahajournals.org/doi/10.1161/...), has been highlighted by an Editorial at ATVB. Congrats, Mary!
August 13, 2025 at 3:03 AM
Very proud of my student @maryschulz.bsky.social, who just received a NOA for her NIH-F31 project to study obesity-induced lymphatic dysfunction and explore novel therapeutics. Also, her recent paper (www.ahajournals.org/doi/10.1161/...), has been highlighted by an Editorial at ATVB. Congrats, Mary!
Reposted by Mary Schulz
scRNAseq of🐭collecting lymphatic vessels😎
Cell type-specific #LymphaticEndothelialCell vs peri-lymphatic myeloid cell contributions of TRPV4 in distinct stages of lymphatic contractile activity
@maryschulz.bsky.social
@jcastorena.bsky.social
#ATVB 2025
www.ahajournals.org/doi/full/10....
Cell type-specific #LymphaticEndothelialCell vs peri-lymphatic myeloid cell contributions of TRPV4 in distinct stages of lymphatic contractile activity
@maryschulz.bsky.social
@jcastorena.bsky.social
#ATVB 2025
www.ahajournals.org/doi/full/10....
June 19, 2025 at 7:07 PM
scRNAseq of🐭collecting lymphatic vessels😎
Cell type-specific #LymphaticEndothelialCell vs peri-lymphatic myeloid cell contributions of TRPV4 in distinct stages of lymphatic contractile activity
@maryschulz.bsky.social
@jcastorena.bsky.social
#ATVB 2025
www.ahajournals.org/doi/full/10....
Cell type-specific #LymphaticEndothelialCell vs peri-lymphatic myeloid cell contributions of TRPV4 in distinct stages of lymphatic contractile activity
@maryschulz.bsky.social
@jcastorena.bsky.social
#ATVB 2025
www.ahajournals.org/doi/full/10....
Grateful for the opportunity to present our research at #LymphaticForum2025 in Chicago and learn about all the cutting edge research in lymphatics! Special thanks to LE&RN for the travel award! @jcastorena.bsky.social
June 14, 2025 at 11:51 PM
Grateful for the opportunity to present our research at #LymphaticForum2025 in Chicago and learn about all the cutting edge research in lymphatics! Special thanks to LE&RN for the travel award! @jcastorena.bsky.social
Excited to share our work on TRPV4 channels in lymphatic contractile function! www.ahajournals.org/doi/10.1161/...
@jcastorena.bsky.social
@ahajournals.bsky.social
@ahascience.bsky.social
@jcastorena.bsky.social
@ahajournals.bsky.social
@ahascience.bsky.social
Regulation of Collecting Lymphatic Vessel Contractile Function by TRPV4 Channels | Arteriosclerosis, Thrombosis, and Vascular Biology
BACKGROUND: Dysregulation of TRPV4 (transient receptor potential vanilloid type 4)–mediated signaling
has been associated with inflammation and tissue fibrosis, both of which are key features
in the p...
www.ahajournals.org
June 2, 2025 at 7:48 PM
Excited to share our work on TRPV4 channels in lymphatic contractile function! www.ahajournals.org/doi/10.1161/...
@jcastorena.bsky.social
@ahajournals.bsky.social
@ahascience.bsky.social
@jcastorena.bsky.social
@ahajournals.bsky.social
@ahascience.bsky.social
Reposted by Mary Schulz
Our study with Mike Davis showing that a component of the lymphatic contractile impairment in db/db mice is mediated by the activation of KATP channels in lymphatic muscle cells, in part due to chronic metabolic stress associated with elevated glucose, is now out.
www.frontiersin.org/journals/phy...
www.frontiersin.org/journals/phy...
Frontiers | Chronic metabolic stress impairs lymphatic contractility via activation of KATP channels in a mouse model of Type-2 diabetes
www.frontiersin.org
May 1, 2025 at 1:51 AM
Our study with Mike Davis showing that a component of the lymphatic contractile impairment in db/db mice is mediated by the activation of KATP channels in lymphatic muscle cells, in part due to chronic metabolic stress associated with elevated glucose, is now out.
www.frontiersin.org/journals/phy...
www.frontiersin.org/journals/phy...
Reposted by Mary Schulz
Our latest publication investigating the role of #palmitoylation in #lymphatic endothelial integrity.
Big shoutout to Silvia Gonzalez-Nieves, Simon GUIGNARD and Thi Nguyen for their incredible work and dedication. 👏👏
www.sciencedirect.com/science/arti...
Big shoutout to Silvia Gonzalez-Nieves, Simon GUIGNARD and Thi Nguyen for their incredible work and dedication. 👏👏
www.sciencedirect.com/science/arti...
Insulin regulates lymphatic endothelial integrity via palmitoylation
Lipid metabolism plays a critical role in lymphatic endothelial cell (LEC) development and vessel maintenance. Altered lipid metabolism is associated …
www.sciencedirect.com
March 12, 2025 at 7:13 PM
Our latest publication investigating the role of #palmitoylation in #lymphatic endothelial integrity.
Big shoutout to Silvia Gonzalez-Nieves, Simon GUIGNARD and Thi Nguyen for their incredible work and dedication. 👏👏
www.sciencedirect.com/science/arti...
Big shoutout to Silvia Gonzalez-Nieves, Simon GUIGNARD and Thi Nguyen for their incredible work and dedication. 👏👏
www.sciencedirect.com/science/arti...
Not science related, but had to document the monumental snowstorm that happened in NOLA yesterday! ❄️
January 22, 2025 at 9:28 PM
Not science related, but had to document the monumental snowstorm that happened in NOLA yesterday! ❄️