Kaabir Ali
@kaabir.bsky.social
PhD student at ENS PSL; studying the role of cytoskeleton in shaping the nuclear architecture during ependymal cell differentiation. #mechanotransduction #devbio #microfluidics
Reposted by Kaabir Ali
Last-minute advert for the Convpaint workshop at I2K by Roman Schwob! Interactive segmentation in @napari.org. Today 2:00 PM CET. Free registration:
www.i2kconference.org/workshops
www.i2kconference.org/workshops
November 18, 2025 at 12:13 PM
Last-minute advert for the Convpaint workshop at I2K by Roman Schwob! Interactive segmentation in @napari.org. Today 2:00 PM CET. Free registration:
www.i2kconference.org/workshops
www.i2kconference.org/workshops
Reposted by Kaabir Ali
1/ 🎉Excited to share our new preprint @vignjeviclab.bsky.social @davidbrueckner.bsky.social :
"Self-organization of tumor heterogeneity and plasticity"
biorxiv.org/content/10.1...
Tumor heterogeneity and plasticity drive metastasis and relapse. How is tumor patterning coordinated?
A thread👇
"Self-organization of tumor heterogeneity and plasticity"
biorxiv.org/content/10.1...
Tumor heterogeneity and plasticity drive metastasis and relapse. How is tumor patterning coordinated?
A thread👇
October 16, 2025 at 9:55 PM
1/ 🎉Excited to share our new preprint @vignjeviclab.bsky.social @davidbrueckner.bsky.social :
"Self-organization of tumor heterogeneity and plasticity"
biorxiv.org/content/10.1...
Tumor heterogeneity and plasticity drive metastasis and relapse. How is tumor patterning coordinated?
A thread👇
"Self-organization of tumor heterogeneity and plasticity"
biorxiv.org/content/10.1...
Tumor heterogeneity and plasticity drive metastasis and relapse. How is tumor patterning coordinated?
A thread👇
Reposted by Kaabir Ali
Registration is open for the next Genome Dynamics course at @institutcurie.bsky.social! This course will explore the full spectrum of genome biology bringing together international experts to share the latest experimental and computational advances ▶️ training.institut-curie.org/courses/Geno...
October 14, 2025 at 9:14 AM
Registration is open for the next Genome Dynamics course at @institutcurie.bsky.social! This course will explore the full spectrum of genome biology bringing together international experts to share the latest experimental and computational advances ▶️ training.institut-curie.org/courses/Geno...
Reposted by Kaabir Ali
1/ 🐣⚒️ To study mechanics, we need to apply prescribed forces - how can we do that in living tissues? I am @eigenp.bsky.social and in this thread I'll highlight our new approach for applying tension on epithelial tissues in vivo!
October 12, 2025 at 12:51 PM
1/ 🐣⚒️ To study mechanics, we need to apply prescribed forces - how can we do that in living tissues? I am @eigenp.bsky.social and in this thread I'll highlight our new approach for applying tension on epithelial tissues in vivo!
Reposted by Kaabir Ali
🔬 Postdoctoral Opportunity in Biomedical Research. #Organoids & #Organs-on-Chip for #IBD and #Personalized #Medicine at #i2mc in #Toulouse, #France at the crossroads of #stem cell biology, #microphysiological systems, and translational medicine.
👉 Apply before Nov. 1rst at [email protected]
👉 Apply before Nov. 1rst at [email protected]
October 11, 2025 at 8:03 AM
🔬 Postdoctoral Opportunity in Biomedical Research. #Organoids & #Organs-on-Chip for #IBD and #Personalized #Medicine at #i2mc in #Toulouse, #France at the crossroads of #stem cell biology, #microphysiological systems, and translational medicine.
👉 Apply before Nov. 1rst at [email protected]
👉 Apply before Nov. 1rst at [email protected]
Reposted by Kaabir Ali
In 2017 I recorded the first episode of the @epigeneticspod.bsky.social. In this article I invite you to explore highlights from 150 episodes and starting a series of Articles that summarises the key lessons I learned from those conversations. #podcast
www.activemotif.com/blog-epigene...
www.activemotif.com/blog-epigene...
What We Learned From 150 Episodes of the Epigenetics Podcast, An Introduction to the Series
In late 2017 I pressed record on the very first episode of the Epigenetics Podcast. My goal was to speak with the field’s leading voices and uncover the stories behind their discoveries. Since then th...
www.activemotif.com
October 6, 2025 at 8:24 AM
In 2017 I recorded the first episode of the @epigeneticspod.bsky.social. In this article I invite you to explore highlights from 150 episodes and starting a series of Articles that summarises the key lessons I learned from those conversations. #podcast
www.activemotif.com/blog-epigene...
www.activemotif.com/blog-epigene...
Reposted by Kaabir Ali
How can we use cell shapes and geometry to study mechanics of tissues?
I'm @juliaeckert.bsky.social, and with this thread, I would like to show you the secrets of cells and tissues. Let’s connect biology with a little bit of physics. Don't be scared and get inspired 😀. #EpithelialMechanics
I'm @juliaeckert.bsky.social, and with this thread, I would like to show you the secrets of cells and tissues. Let’s connect biology with a little bit of physics. Don't be scared and get inspired 😀. #EpithelialMechanics
September 13, 2025 at 7:15 AM
How can we use cell shapes and geometry to study mechanics of tissues?
I'm @juliaeckert.bsky.social, and with this thread, I would like to show you the secrets of cells and tissues. Let’s connect biology with a little bit of physics. Don't be scared and get inspired 😀. #EpithelialMechanics
I'm @juliaeckert.bsky.social, and with this thread, I would like to show you the secrets of cells and tissues. Let’s connect biology with a little bit of physics. Don't be scared and get inspired 😀. #EpithelialMechanics
Reposted by Kaabir Ali
We're happy to announce the 2025 International OME-NGFF workshop 🎉
📅 Dates:
- Symposium: Nov 10–11, 2025
- Hackathon: Nov 12–14, 2025
📍 Location: Zurich, Switzerland
Full details & registration: www.biovisioncenter.uzh.ch/en/events/Up...
#bioimaging #openscience #OMENGFF #OMEZarr
(1/x 🧵)
📅 Dates:
- Symposium: Nov 10–11, 2025
- Hackathon: Nov 12–14, 2025
📍 Location: Zurich, Switzerland
Full details & registration: www.biovisioncenter.uzh.ch/en/events/Up...
#bioimaging #openscience #OMENGFF #OMEZarr
(1/x 🧵)
August 25, 2025 at 9:07 AM
We're happy to announce the 2025 International OME-NGFF workshop 🎉
📅 Dates:
- Symposium: Nov 10–11, 2025
- Hackathon: Nov 12–14, 2025
📍 Location: Zurich, Switzerland
Full details & registration: www.biovisioncenter.uzh.ch/en/events/Up...
#bioimaging #openscience #OMENGFF #OMEZarr
(1/x 🧵)
📅 Dates:
- Symposium: Nov 10–11, 2025
- Hackathon: Nov 12–14, 2025
📍 Location: Zurich, Switzerland
Full details & registration: www.biovisioncenter.uzh.ch/en/events/Up...
#bioimaging #openscience #OMENGFF #OMEZarr
(1/x 🧵)
Reposted by Kaabir Ali
Excited to share our new publication in Nature Physics about the mechanical memory of morphology in confined migrating cells by @kyohalie.bsky.social 🥳
Super fun collab with @davidbrueckner.bsky.social and @gcharras.bsky.social 👏🏻
Enjoy the reading www.nature.com/articles/s41...
Super fun collab with @davidbrueckner.bsky.social and @gcharras.bsky.social 👏🏻
Enjoy the reading www.nature.com/articles/s41...
The actin cortex acts as a mechanical memory of morphology in confined migrating cells - Nature Physics
Cells often navigate through confined spaces. Now it is shown that cells retain a mechanical memory of previous confinement events, which makes them more efficient at migrating through narrow microenv...
www.nature.com
August 25, 2025 at 9:59 AM
Excited to share our new publication in Nature Physics about the mechanical memory of morphology in confined migrating cells by @kyohalie.bsky.social 🥳
Super fun collab with @davidbrueckner.bsky.social and @gcharras.bsky.social 👏🏻
Enjoy the reading www.nature.com/articles/s41...
Super fun collab with @davidbrueckner.bsky.social and @gcharras.bsky.social 👏🏻
Enjoy the reading www.nature.com/articles/s41...
Pas tout à fait! Les gens sont conscients de la situation, mais ils sont indifférents à la souffrance humaine. Lors d'un récent sondage, interrogés sur les informations faisant état de famine et de souffrances au sein de la population, la majorité des personnes interrogées n'étaient pas inquiètes.
Bombardements, famine, destructions : les images de Gaza circulent partout dans le monde.
En Israël, elles n’occupent pas ou plus l’espace public.
Le choc du 7 octobre a refermé une société sur elle-même.
➡️ https://l.franceculture.fr/ykU
En Israël, elles n’occupent pas ou plus l’espace public.
Le choc du 7 octobre a refermé une société sur elle-même.
➡️ https://l.franceculture.fr/ykU
August 19, 2025 at 8:45 PM
Pas tout à fait! Les gens sont conscients de la situation, mais ils sont indifférents à la souffrance humaine. Lors d'un récent sondage, interrogés sur les informations faisant état de famine et de souffrances au sein de la population, la majorité des personnes interrogées n'étaient pas inquiètes.
Reposted by Kaabir Ali
To have this paper appear the same day that RFK Jr is canceling all mRNA vaccine funding is further indication that irony is not dead, even though we might all be soon.
August 6, 2025 at 12:35 AM
To have this paper appear the same day that RFK Jr is canceling all mRNA vaccine funding is further indication that irony is not dead, even though we might all be soon.
Reposted by Kaabir Ali
I think the honest answer (but a sceptical one) to this question is: probably not (we can't know right now). But I can answer two other questions. (1) Is Avi Loeb's late alien work serious and honest? NO. (2) Is this damaging science when Loeb uses his authority as a Harvard academic? YES.
July 31, 2025 at 8:40 AM
I think the honest answer (but a sceptical one) to this question is: probably not (we can't know right now). But I can answer two other questions. (1) Is Avi Loeb's late alien work serious and honest? NO. (2) Is this damaging science when Loeb uses his authority as a Harvard academic? YES.
Reposted by Kaabir Ali
The front page of Le Monde newspaper today.
July 24, 2025 at 2:23 PM
The front page of Le Monde newspaper today.
Reposted by Kaabir Ali
If you’ve been following this account closely, you might already know methods to probe mechanics in vitro, but what about in live embryos?
I’m @amichaut.bsky.social, and I’m going to share a few great papers on this aspect of #EpithelialMechanics.
I’m @amichaut.bsky.social, and I’m going to share a few great papers on this aspect of #EpithelialMechanics.
July 20, 2025 at 7:01 AM
If you’ve been following this account closely, you might already know methods to probe mechanics in vitro, but what about in live embryos?
I’m @amichaut.bsky.social, and I’m going to share a few great papers on this aspect of #EpithelialMechanics.
I’m @amichaut.bsky.social, and I’m going to share a few great papers on this aspect of #EpithelialMechanics.
Reposted by Kaabir Ali
BREAKING: Zeteo has released, globally, the film the BBC so controversially refused to air.
"Gaza: Doctors Under Attack" is now available to watch in full at gazadoctors.film and zeteo.com.
Here's the trailer:
"Gaza: Doctors Under Attack" is now available to watch in full at gazadoctors.film and zeteo.com.
Here's the trailer:
July 2, 2025 at 9:11 PM
BREAKING: Zeteo has released, globally, the film the BBC so controversially refused to air.
"Gaza: Doctors Under Attack" is now available to watch in full at gazadoctors.film and zeteo.com.
Here's the trailer:
"Gaza: Doctors Under Attack" is now available to watch in full at gazadoctors.film and zeteo.com.
Here's the trailer:
Reposted by Kaabir Ali
It's an interesting phenomenon that some of the deepest questions about how life works have become what looks like impossibly obscure molecular biology stuck right at the back of Nature, which will never get covered by the science media. Like this. /1
www.nature.com/articles/s41...
www.nature.com/articles/s41...
DNA-guided transcription factor interactions extend human gene regulatory code - Nature
A large-scale analysis of DNA-bound transcription factors (TFs) shows how the presence of DNA markedly affects the landscape of TF interactions, and identifies composite motifs that are recognized by ...
www.nature.com
May 31, 2025 at 6:06 PM
It's an interesting phenomenon that some of the deepest questions about how life works have become what looks like impossibly obscure molecular biology stuck right at the back of Nature, which will never get covered by the science media. Like this. /1
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Kaabir Ali
Boom!!! 💥💥💥💥
EpiSci - 🧬 - 🧪 - Expansion in situ genome sequencing links nuclear abnormalities to aberrant chromatin regulation
@Zachary D. Chiang. @Ajay S.Labade @jbuenrostro.bsky.social
www.science.org/doi/10.1126/...
EpiSci - 🧬 - 🧪 - Expansion in situ genome sequencing links nuclear abnormalities to aberrant chromatin regulation
@Zachary D. Chiang. @Ajay S.Labade @jbuenrostro.bsky.social
www.science.org/doi/10.1126/...
Expansion in situ genome sequencing links nuclear abnormalities to aberrant chromatin regulation
Microscopy and genomics are used to characterize cell function, but approaches to connect the two types of information are lacking, particularly at subnuclear resolution. Here, we describe expansion i...
www.science.org
May 29, 2025 at 7:35 PM
Boom!!! 💥💥💥💥
EpiSci - 🧬 - 🧪 - Expansion in situ genome sequencing links nuclear abnormalities to aberrant chromatin regulation
@Zachary D. Chiang. @Ajay S.Labade @jbuenrostro.bsky.social
www.science.org/doi/10.1126/...
EpiSci - 🧬 - 🧪 - Expansion in situ genome sequencing links nuclear abnormalities to aberrant chromatin regulation
@Zachary D. Chiang. @Ajay S.Labade @jbuenrostro.bsky.social
www.science.org/doi/10.1126/...
Reposted by Kaabir Ali
Earlier this year, with Google DeepMind, we held the AlphaFold Education Summit to increase and strengthen global capacity through train-the-trainer sessions & the co-development of further #AlphaFold training.
Now, we can share the free course materials with you: www.ebi.ac.uk/training/mat...
🧪🖥️🧬
Now, we can share the free course materials with you: www.ebi.ac.uk/training/mat...
🧪🖥️🧬
May 29, 2025 at 2:11 PM
Earlier this year, with Google DeepMind, we held the AlphaFold Education Summit to increase and strengthen global capacity through train-the-trainer sessions & the co-development of further #AlphaFold training.
Now, we can share the free course materials with you: www.ebi.ac.uk/training/mat...
🧪🖥️🧬
Now, we can share the free course materials with you: www.ebi.ac.uk/training/mat...
🧪🖥️🧬
Reposted by Kaabir Ali
Many cells during development are exposed to caspase activation and yet survive. Why some die and not others ? We found out that the memory of previous caspase activation bias significantly later death comitment and bias death distribution and single cell decision
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
May 21, 2025 at 9:40 AM
Many cells during development are exposed to caspase activation and yet survive. Why some die and not others ? We found out that the memory of previous caspase activation bias significantly later death comitment and bias death distribution and single cell decision
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Kaabir Ali
All of NIH funding to Northwestern University is frozen. This pause includes noncompeting approved funding, new and competing grants with fundable scores. No reimbursements for money already spent have been received since March. This situation is rarely reported so please Please get the word out!
May 23, 2025 at 5:56 PM
All of NIH funding to Northwestern University is frozen. This pause includes noncompeting approved funding, new and competing grants with fundable scores. No reimbursements for money already spent have been received since March. This situation is rarely reported so please Please get the word out!
Reposted by Kaabir Ali
Genetically encoded reporters of actin filament organization in living cells and tissues: Cell www.cell.com/cell/fulltex...
Genetically encoded reporters of actin filament organization in living cells and tissues
Tailoring genetic fusions of widely used actin localization reporters by constraining
the mobility of the fluorescent proteins allows measurements of actin filament organization
in living cells and ti...
www.cell.com
April 5, 2025 at 7:10 AM
Genetically encoded reporters of actin filament organization in living cells and tissues: Cell www.cell.com/cell/fulltex...
Reposted by Kaabir Ali
🎉 Excited to share our new work: “Adhesion-driven tissue rigidification triggers epithelial cell polarity”, now on @biorxivpreprint.bsky.social !
A huge thank you to @nicolettapetridou.bsky.social, Bernat, @crisp-c.bsky.social, Adrián, and everyone involved! 🙌
🧵⤵️
A huge thank you to @nicolettapetridou.bsky.social, Bernat, @crisp-c.bsky.social, Adrián, and everyone involved! 🙌
🧵⤵️
March 27, 2025 at 2:16 PM
🎉 Excited to share our new work: “Adhesion-driven tissue rigidification triggers epithelial cell polarity”, now on @biorxivpreprint.bsky.social !
A huge thank you to @nicolettapetridou.bsky.social, Bernat, @crisp-c.bsky.social, Adrián, and everyone involved! 🙌
🧵⤵️
A huge thank you to @nicolettapetridou.bsky.social, Bernat, @crisp-c.bsky.social, Adrián, and everyone involved! 🙌
🧵⤵️
Reposted by Kaabir Ali
I am delighted to share with you my first postdoc paper, which has now been published in @currentbiology.bsky.social!
www.cell.com/current-biol...
Thanks to everyone who contributed: A. Chamolly, @aurelienvilledieu.bsky.social, F. Corson and @jeromegros.bsky.
www.cell.com/current-biol...
Thanks to everyone who contributed: A. Chamolly, @aurelienvilledieu.bsky.social, F. Corson and @jeromegros.bsky.
A tension-induced morphological transition shapes the avian extra-embryonic territory
Michaut et al. show that the tension produced during epiboly elastically stretches
the extra-embryonic (EE) territory, while the embryo proper (EP) remains unaffected.
Although the whole epiblast (EP ...
www.cell.com
March 13, 2025 at 11:32 AM
I am delighted to share with you my first postdoc paper, which has now been published in @currentbiology.bsky.social!
www.cell.com/current-biol...
Thanks to everyone who contributed: A. Chamolly, @aurelienvilledieu.bsky.social, F. Corson and @jeromegros.bsky.
www.cell.com/current-biol...
Thanks to everyone who contributed: A. Chamolly, @aurelienvilledieu.bsky.social, F. Corson and @jeromegros.bsky.
Reposted by Kaabir Ali
🚨 Paper Alert 🚨
Absolutely delighted to share our last paper on "spatial mechano-transcriptomics" @naturemethods👇!!
www.nature.com/articles/s41...
Absolutely delighted to share our last paper on "spatial mechano-transcriptomics" @naturemethods👇!!
www.nature.com/articles/s41...
A computational pipeline for spatial mechano-transcriptomics - Nature Methods
The authors present a computational framework that leverages mechanical force inference and spatial transcriptomics to enable analyses of the interplay between the transcriptomic and mechanical state.
www.nature.com
March 17, 2025 at 12:53 PM
🚨 Paper Alert 🚨
Absolutely delighted to share our last paper on "spatial mechano-transcriptomics" @naturemethods👇!!
www.nature.com/articles/s41...
Absolutely delighted to share our last paper on "spatial mechano-transcriptomics" @naturemethods👇!!
www.nature.com/articles/s41...
Reposted by Kaabir Ali
Happy to share our review on methodology for measuring and manipulating mechanical forces with specific focus on developmental biology! Congrats to authors @clemvilleneuve.bsky.social @mccreery.bsky.social and hats off to the community for developing awesome tools www.nature.com/articles/s41...
Measuring and manipulating mechanical forces during development - Nature Cell Biology
This Review discusses the recent advances in experimental approaches to interrogate the mechanical forces that mediate tissue deformations during development, highlighting the insights afforded at bot...
www.nature.com
March 10, 2025 at 1:33 PM
Happy to share our review on methodology for measuring and manipulating mechanical forces with specific focus on developmental biology! Congrats to authors @clemvilleneuve.bsky.social @mccreery.bsky.social and hats off to the community for developing awesome tools www.nature.com/articles/s41...