Ian Wong Lab at Brown University
@ianywonglab.bsky.social
Biomedical engineering lab at Brown University. Biomaterials, mechanobiology and computer vision for cancer cell invasion. Also, micro / nano fab and 3D printing.
Pinned
Focus on new faculty: Dhananjay Bhaskar plays with the ‘shape’ of data - College of Engineering - University of Wisconsin-Madison
Dhananjay Bhaskar can’t hide his enthusiasm on the other end of the video call as he carries his laptop down the hallways of Yale University’s new Wu Tsai Institute building. He stops in front of...
engineering.wisc.edu
University of Wisconsin-Madison feature on Dhananjay Bhaskar PhD '21:
engineering.wisc.edu/news/focus-o...
engineering.wisc.edu/news/focus-o...
Reposted by Ian Wong Lab at Brown University
Still posting cytoskeleton videos, it seems. Actin this time.
Sample: Lifeact-eGFP in HeLa cells.
Modality: Airyscan confocal
Timestamp is mm:ss and the scale bar is 5 µm.
Sample: Lifeact-eGFP in HeLa cells.
Modality: Airyscan confocal
Timestamp is mm:ss and the scale bar is 5 µm.
November 23, 2025 at 3:21 AM
Still posting cytoskeleton videos, it seems. Actin this time.
Sample: Lifeact-eGFP in HeLa cells.
Modality: Airyscan confocal
Timestamp is mm:ss and the scale bar is 5 µm.
Sample: Lifeact-eGFP in HeLa cells.
Modality: Airyscan confocal
Timestamp is mm:ss and the scale bar is 5 µm.
Reposted by Ian Wong Lab at Brown University
The law of the jungle.
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
November 21, 2025 at 1:07 PM
The law of the jungle.
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
Reposted by Ian Wong Lab at Brown University
I guess it never gets old...bc we love #CellMigration
ATP has many roles: energy currency, hydrotrope, and *danger signal*
Immune cells are faster after ATP exposure, F-actin (cyan) goes to the rear for nitro boost!
www.science.org/doi/full/10....
@focalplane.bsky.social #fluorescencefriday 🧪🔬
ATP has many roles: energy currency, hydrotrope, and *danger signal*
Immune cells are faster after ATP exposure, F-actin (cyan) goes to the rear for nitro boost!
www.science.org/doi/full/10....
@focalplane.bsky.social #fluorescencefriday 🧪🔬
November 14, 2025 at 8:38 PM
I guess it never gets old...bc we love #CellMigration
ATP has many roles: energy currency, hydrotrope, and *danger signal*
Immune cells are faster after ATP exposure, F-actin (cyan) goes to the rear for nitro boost!
www.science.org/doi/full/10....
@focalplane.bsky.social #fluorescencefriday 🧪🔬
ATP has many roles: energy currency, hydrotrope, and *danger signal*
Immune cells are faster after ATP exposure, F-actin (cyan) goes to the rear for nitro boost!
www.science.org/doi/full/10....
@focalplane.bsky.social #fluorescencefriday 🧪🔬
Reposted by Ian Wong Lab at Brown University
Flashback #FluorescenceFriday to some of the first light-sheet imaging we were doing. Video shows the collecting duct system of the developing kidney labeled with a pan-cytokeratin antibody. Courtesy of former talented technician Deanna Hardesty.
November 7, 2025 at 4:43 PM
Flashback #FluorescenceFriday to some of the first light-sheet imaging we were doing. Video shows the collecting duct system of the developing kidney labeled with a pan-cytokeratin antibody. Courtesy of former talented technician Deanna Hardesty.
Reposted by Ian Wong Lab at Brown University
What a crazy cool paper! First author @pierreucla.bsky.social with a large crew knocked it out of the park. (GIF below from @the.3i.social LLS) Quantifying cell traction forces at the single-fiber scale in 3D: An approach based on deformable photopolymerized fiber arrays www.pnas.org/doi/10.1073/...
November 13, 2025 at 6:21 PM
What a crazy cool paper! First author @pierreucla.bsky.social with a large crew knocked it out of the park. (GIF below from @the.3i.social LLS) Quantifying cell traction forces at the single-fiber scale in 3D: An approach based on deformable photopolymerized fiber arrays www.pnas.org/doi/10.1073/...
Reposted by Ian Wong Lab at Brown University
Comment by Prof @icouzin.bsky.social that explores how collective intelligence emerges from local interactions in animal groups, and how these principles inform the design of swarm robotic systems. @natureportfolio.nature.com
@natcomms.nature.com #robotics
www.nature.com/articles/s41...
@natcomms.nature.com #robotics
www.nature.com/articles/s41...
Collective intelligence in animals and robots - Nature Communications
This commentary explores how collective intelligence arises from local interactions in animal groups and how these principles inform the design of swarm robotic systems, addressing the challenge of ac...
www.nature.com
November 11, 2025 at 1:14 PM
Comment by Prof @icouzin.bsky.social that explores how collective intelligence emerges from local interactions in animal groups, and how these principles inform the design of swarm robotic systems. @natureportfolio.nature.com
@natcomms.nature.com #robotics
www.nature.com/articles/s41...
@natcomms.nature.com #robotics
www.nature.com/articles/s41...
Honored to present last week at the Korea-US Collaborative Research Fund Investigator Meeting (kufhls.org)
Delighted to share our consortium's vision for bioengineering tumor models, alongside many stimulating talks by Korean and U.S. researchers on biotechnology
Delighted to share our consortium's vision for bioengineering tumor models, alongside many stimulating talks by Korean and U.S. researchers on biotechnology
November 9, 2025 at 8:57 PM
Honored to present last week at the Korea-US Collaborative Research Fund Investigator Meeting (kufhls.org)
Delighted to share our consortium's vision for bioengineering tumor models, alongside many stimulating talks by Korean and U.S. researchers on biotechnology
Delighted to share our consortium's vision for bioengineering tumor models, alongside many stimulating talks by Korean and U.S. researchers on biotechnology
Reposted by Ian Wong Lab at Brown University
Postdoc Jiwon Kim from the @ianywonglab.bsky.social was named one of 30 female Rising Stars in MechE, and invited to a workshop to develop career skills, connect with a cohort of peers, and engage with mentors in anticipation of future careers in academia. engineering.brown.edu/news/2025-10...
Kim chosen Rising Star in Mechanical Engineering
engineering.brown.edu
October 27, 2025 at 8:15 PM
Postdoc Jiwon Kim from the @ianywonglab.bsky.social was named one of 30 female Rising Stars in MechE, and invited to a workshop to develop career skills, connect with a cohort of peers, and engage with mentors in anticipation of future careers in academia. engineering.brown.edu/news/2025-10...
Wong lab members are off to the Biomedical Engineering Society (BMES) 2025 Meeting in San Diego! Looking forward to presenting our latest work #BMES2025, @brownengineering.bsky.social @jiwon-kim.bsky.social @htjeong.bsky.social
October 7, 2025 at 8:24 PM
Wong lab members are off to the Biomedical Engineering Society (BMES) 2025 Meeting in San Diego! Looking forward to presenting our latest work #BMES2025, @brownengineering.bsky.social @jiwon-kim.bsky.social @htjeong.bsky.social
Reposted by Ian Wong Lab at Brown University
New Online! The advent of confocal laser scanning microscopy in biological research
The advent of confocal laser scanning microscopy in biological research
Nature Reviews Molecular Cell Biology, Published online: 01 October 2025; doi:10.1038/s41580-025-00905-5The advent of laser-scanning confocal microscopy revolutionized cell biology, offering unprecedented resolution and depth and enabling scientists to visualize cellular structures in 3D.
bit.ly
October 1, 2025 at 12:03 PM
New Online! The advent of confocal laser scanning microscopy in biological research
Reposted by Ian Wong Lab at Brown University
I’m not sure as a community we **truely** acknowledged how powerful the #CellMigrationSeminarSeries series was at keeping us connected at such an uncertain time. Thank-you @ankita13jha.bsky.social @adamshellard.bsky.social @drjenmitchell.bsky.social & @simplythebex.bsky.social
September 29, 2025 at 2:07 AM
I’m not sure as a community we **truely** acknowledged how powerful the #CellMigrationSeminarSeries series was at keeping us connected at such an uncertain time. Thank-you @ankita13jha.bsky.social @adamshellard.bsky.social @drjenmitchell.bsky.social & @simplythebex.bsky.social
Reposted by Ian Wong Lab at Brown University
University of Wisconsin-Madison feature on Dhananjay Bhaskar PhD '21:
engineering.wisc.edu/news/focus-o...
engineering.wisc.edu/news/focus-o...
Focus on new faculty: Dhananjay Bhaskar plays with the ‘shape’ of data - College of Engineering - University of Wisconsin-Madison
Dhananjay Bhaskar can’t hide his enthusiasm on the other end of the video call as he carries his laptop down the hallways of Yale University’s new Wu Tsai Institute building. He stops in front of...
engineering.wisc.edu
September 24, 2025 at 6:30 PM
University of Wisconsin-Madison feature on Dhananjay Bhaskar PhD '21:
engineering.wisc.edu/news/focus-o...
engineering.wisc.edu/news/focus-o...
Reposted by Ian Wong Lab at Brown University
I use a video of #Maru in my talks on confined migration- @retof.bsky.social sent it to me ‘this cat looks like your cells’. 😂 I always have yo explain who #Maru is!
a cat is playing with a box that says " dry " on it
ALT: a cat is playing with a box that says " dry " on it
media.tenor.com
September 12, 2025 at 6:03 AM
I use a video of #Maru in my talks on confined migration- @retof.bsky.social sent it to me ‘this cat looks like your cells’. 😂 I always have yo explain who #Maru is!
Reposted by Ian Wong Lab at Brown University
New perspective in @jcb.org by @maikbischoff.bsky.social & @mayorlab.bsky.social about how mesenchymal cells use contact-dependent rules to generate swarm-like behaviors, patterns & organ forms. rupress.org/jcb/article/...
#CellBio #CellMigration #Morphogenesis #Development #Science
#CellBio #CellMigration #Morphogenesis #Development #Science
September 23, 2025 at 6:52 PM
New perspective in @jcb.org by @maikbischoff.bsky.social & @mayorlab.bsky.social about how mesenchymal cells use contact-dependent rules to generate swarm-like behaviors, patterns & organ forms. rupress.org/jcb/article/...
#CellBio #CellMigration #Morphogenesis #Development #Science
#CellBio #CellMigration #Morphogenesis #Development #Science
Reposted by Ian Wong Lab at Brown University
📕 Our Intermediate Filaments collection explores recent advances in intermediate filament research, focusing on lamins, keratins and vimentin. Explore new and recent JCB studies to accompany this week's European Intermediate Filament Meeting 👉 rupress.org/jcb/collecti...
#Euro-IF
#Euro-IF
September 23, 2025 at 2:15 PM
📕 Our Intermediate Filaments collection explores recent advances in intermediate filament research, focusing on lamins, keratins and vimentin. Explore new and recent JCB studies to accompany this week's European Intermediate Filament Meeting 👉 rupress.org/jcb/collecti...
#Euro-IF
#Euro-IF
Reposted by Ian Wong Lab at Brown University
In squash, the nick shot is nearly impossible to return—the ball hits the corner and doesn’t bounce. 🎾 In a new Science Sessions episode, Roberto Zenit explains the physics behind it and its surprising link to safety gear. Listen: www.pnas.org/post/podcast...
September 22, 2025 at 8:53 PM
In squash, the nick shot is nearly impossible to return—the ball hits the corner and doesn’t bounce. 🎾 In a new Science Sessions episode, Roberto Zenit explains the physics behind it and its surprising link to safety gear. Listen: www.pnas.org/post/podcast...
Reposted by Ian Wong Lab at Brown University
Expression of vimentin intermediate filaments in epithelial cells promotes cell migration and cell matrix interaction in 3D https://www.biorxiv.org/content/10.1101/2025.09.18.677142v1
September 19, 2025 at 11:48 AM
Expression of vimentin intermediate filaments in epithelial cells promotes cell migration and cell matrix interaction in 3D https://www.biorxiv.org/content/10.1101/2025.09.18.677142v1
Reposted by Ian Wong Lab at Brown University
A full-scale renovation of Prince Lab, transforming it into a dynamic and central campus hub for project-based learning, cutting-edge research and engineering innovation, will be launched by Brown University, with a generous gift from the Lassonde Family Foundation. www.brown.edu/news/2025-09...
Generous gift to fund Prince Lab renovation at Brown, creating the Lassonde Innovation and Design Hub
Support from the Lassonde Family Foundation will enable a reimagined campus hub in the School of Engineering complex for Brown makers, engineers, entrepreneurs and artists to innovate and create.
www.brown.edu
September 18, 2025 at 5:41 PM
A full-scale renovation of Prince Lab, transforming it into a dynamic and central campus hub for project-based learning, cutting-edge research and engineering innovation, will be launched by Brown University, with a generous gift from the Lassonde Family Foundation. www.brown.edu/news/2025-09...
Reposted by Ian Wong Lab at Brown University
Happy Postdoc Appreciation Week to all of our postdocs! #PostdocAppreciationWeek
September 17, 2025 at 9:52 PM
Happy Postdoc Appreciation Week to all of our postdocs! #PostdocAppreciationWeek
Reposted by Ian Wong Lab at Brown University
Tissues transition between solid & fluid states in development & disease; cytoplasm turns crowded or inert to literally 'solidify'. Any connections? Turns out nothing's known. @sameerthukral.bsky.social & @bipashadey29.bsky.social pulled this review off brilliantly with a conceptual synthesis.
September 15, 2025 at 2:12 AM
Tissues transition between solid & fluid states in development & disease; cytoplasm turns crowded or inert to literally 'solidify'. Any connections? Turns out nothing's known. @sameerthukral.bsky.social & @bipashadey29.bsky.social pulled this review off brilliantly with a conceptual synthesis.
Reposted by Ian Wong Lab at Brown University
Epithelial-to-mesenchymal transition or EMT is an integral part of development in animals. In this beautifully illustrated review from the lab of Magali Suzanne, they describe and compare and contrast the cellular mechanism of EMT across the different model organisms.
doi.org/10.1016/j.cd...
doi.org/10.1016/j.cd...
September 12, 2025 at 4:15 PM
Epithelial-to-mesenchymal transition or EMT is an integral part of development in animals. In this beautifully illustrated review from the lab of Magali Suzanne, they describe and compare and contrast the cellular mechanism of EMT across the different model organisms.
doi.org/10.1016/j.cd...
doi.org/10.1016/j.cd...
Reposted by Ian Wong Lab at Brown University
New findings in Science suggest that rodents owe much of their evolutionary success to their thumb-nail (the first digit, D1), an adaptation that gave them dexterous hands for cracking seeds and nuts.
Learn more in this week's issue: https://scim.ag/46caVho
Learn more in this week's issue: https://scim.ag/46caVho
September 4, 2025 at 6:05 PM
New findings in Science suggest that rodents owe much of their evolutionary success to their thumb-nail (the first digit, D1), an adaptation that gave them dexterous hands for cracking seeds and nuts.
Learn more in this week's issue: https://scim.ag/46caVho
Learn more in this week's issue: https://scim.ag/46caVho
Reposted by Ian Wong Lab at Brown University
Our September issue is here! rupress.org/jcb/issue/22...
Airyscan super-resolution immunofluorescence image of HeLa cells stained for two types of intermediate filaments: vimentin (magenta) & keratin-8 (cyan). From Pasolli, @joycemeiri.bsky.social, Akhmanova et al. rupress.org/jcb/article/...
Airyscan super-resolution immunofluorescence image of HeLa cells stained for two types of intermediate filaments: vimentin (magenta) & keratin-8 (cyan). From Pasolli, @joycemeiri.bsky.social, Akhmanova et al. rupress.org/jcb/article/...
September 1, 2025 at 2:03 PM
Our September issue is here! rupress.org/jcb/issue/22...
Airyscan super-resolution immunofluorescence image of HeLa cells stained for two types of intermediate filaments: vimentin (magenta) & keratin-8 (cyan). From Pasolli, @joycemeiri.bsky.social, Akhmanova et al. rupress.org/jcb/article/...
Airyscan super-resolution immunofluorescence image of HeLa cells stained for two types of intermediate filaments: vimentin (magenta) & keratin-8 (cyan). From Pasolli, @joycemeiri.bsky.social, Akhmanova et al. rupress.org/jcb/article/...
Reposted by Ian Wong Lab at Brown University
Automated optogenetic control of hundreds of cells in parallel. Each cell is individually steered, collectively acting as a "tissue printer". Preprint & code out! www.biorxiv.org/content/10.1...
August 21, 2025 at 8:16 PM
Automated optogenetic control of hundreds of cells in parallel. Each cell is individually steered, collectively acting as a "tissue printer". Preprint & code out! www.biorxiv.org/content/10.1...