Joana Ferreira da Silva
@ferreiradasilvaj.bsky.social
PostDoc @BKleinstiver lab at Mass Gen Hospital & Harvard Med School.
@EMBO Fellow. Previously: PhD @CeMM_News
🧬 repair & ✂️ genome editing enthusiast
@EMBO Fellow. Previously: PhD @CeMM_News
🧬 repair & ✂️ genome editing enthusiast
Reposted by Joana Ferreira da Silva
So excited to share our new paper out today in @nature.com. We repurposed R2 retrotransposons to create STITCHR, a tool that can make virtually any kind of edit in mammalian genomes including the scarless multi-kilobase scale insertions 🧵
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reprogramming site-specific retrotransposon activity to new DNA sites - Nature
A study of retrotransposon activity repurposes a retroelement called R2Tocc to create a programmable system called STITCHR that enables diverse genome edits including efficient, scarless large pa...
www.nature.com
April 9, 2025 at 5:10 PM
So excited to share our new paper out today in @nature.com. We repurposed R2 retrotransposons to create STITCHR, a tool that can make virtually any kind of edit in mammalian genomes including the scarless multi-kilobase scale insertions 🧵
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Joana Ferreira da Silva
Interested in learning more about genome editing tool dev & their application to treat human diseases? 🧬 🏥
We're hiring graduating seniors who are seeking ~2 years of post-bac research experience.
If you're interested in gaining experience in next gen medicines, please reach out and apply!
Link 👇
We're hiring graduating seniors who are seeking ~2 years of post-bac research experience.
If you're interested in gaining experience in next gen medicines, please reach out and apply!
Link 👇
Research Technician I - Center for Genomic Medicine
Site: The General Hospital Corporation At Mass General Brigham, we know it takes a surprising range of talented professionals to advance our mission—from doctors, nurses, business people and tech expe...
massgeneralbrigham.wd1.myworkdayjobs.com
March 13, 2025 at 4:39 PM
Interested in learning more about genome editing tool dev & their application to treat human diseases? 🧬 🏥
We're hiring graduating seniors who are seeking ~2 years of post-bac research experience.
If you're interested in gaining experience in next gen medicines, please reach out and apply!
Link 👇
We're hiring graduating seniors who are seeking ~2 years of post-bac research experience.
If you're interested in gaining experience in next gen medicines, please reach out and apply!
Link 👇
Reposted by Joana Ferreira da Silva
🚨 Interested in precise, multi-kilobase scale insertions into the genome?
Check out our detailed protocol describing PASTE, out in Nature Protocols @natureportfolio.bsky.social
⬇️
www.nature.com/articles/s41...
Check out our detailed protocol describing PASTE, out in Nature Protocols @natureportfolio.bsky.social
⬇️
www.nature.com/articles/s41...
Precise kilobase-scale genomic insertions in mammalian cells using PASTE - Nature Protocols
Programmable addition via site-specific targeting elements (PASTE) combines the specificity, efficiency and cargo size benefits of site-specific integrases with the programmability of prime editing fo...
www.nature.com
December 16, 2024 at 3:17 PM
🚨 Interested in precise, multi-kilobase scale insertions into the genome?
Check out our detailed protocol describing PASTE, out in Nature Protocols @natureportfolio.bsky.social
⬇️
www.nature.com/articles/s41...
Check out our detailed protocol describing PASTE, out in Nature Protocols @natureportfolio.bsky.social
⬇️
www.nature.com/articles/s41...