European Headache Federation
@ehfofficial.bsky.social
Improving awareness of headache disorders and their impact across Europe. Official journal: Journal of Headache and Pain
Migraine and pregnancy-related headaches are independent risk factors for serious complications, including a significantly increased risk of stroke and other cardiovascular events during pregnancy and the postpartum period.
Full details: doi.org/10.1186/s101...
Full details: doi.org/10.1186/s101...
November 23, 2025 at 10:25 PM
Migraine and pregnancy-related headaches are independent risk factors for serious complications, including a significantly increased risk of stroke and other cardiovascular events during pregnancy and the postpartum period.
Full details: doi.org/10.1186/s101...
Full details: doi.org/10.1186/s101...
Spreading Depolarization (SD) can trigger seizure-like activity in the hippocampus. This suggests a probable direct mechanism for migraine-aura triggered seizures (migralepsy).
Read more: doi.org/10.1186/s101...
Read more: doi.org/10.1186/s101...
November 22, 2025 at 2:15 PM
Spreading Depolarization (SD) can trigger seizure-like activity in the hippocampus. This suggests a probable direct mechanism for migraine-aura triggered seizures (migralepsy).
Read more: doi.org/10.1186/s101...
Read more: doi.org/10.1186/s101...
New findings link Familial Hemiplegic Migraine type 2 (FHM2) to a significantly impaired glymphatic system. This study identifies abnormal neurovascular coupling as a key factor, opening new avenues for understanding migraine pathophysiology.
Read the full article: doi.org/10.1186/s101...
Read the full article: doi.org/10.1186/s101...
November 22, 2025 at 10:07 AM
New findings link Familial Hemiplegic Migraine type 2 (FHM2) to a significantly impaired glymphatic system. This study identifies abnormal neurovascular coupling as a key factor, opening new avenues for understanding migraine pathophysiology.
Read the full article: doi.org/10.1186/s101...
Read the full article: doi.org/10.1186/s101...
Abnormal brain iron deposition in patients with new daily persistent #headache (NDPH).
Findings indicate that the metabolic disorder of iron deposition in specific areas of the brain may be related to the underlying pathogenesis of patients with NDPH.
Full text here: rdcu.be/eOLcO
Findings indicate that the metabolic disorder of iron deposition in specific areas of the brain may be related to the underlying pathogenesis of patients with NDPH.
Full text here: rdcu.be/eOLcO
November 7, 2025 at 11:17 AM
Abnormal brain iron deposition in patients with new daily persistent #headache (NDPH).
Findings indicate that the metabolic disorder of iron deposition in specific areas of the brain may be related to the underlying pathogenesis of patients with NDPH.
Full text here: rdcu.be/eOLcO
Findings indicate that the metabolic disorder of iron deposition in specific areas of the brain may be related to the underlying pathogenesis of patients with NDPH.
Full text here: rdcu.be/eOLcO
How common chronic headache disorders are and how much productivity loss they are causing within administrative bodies?
Compared with TTH, #migraine compromises brain health more severely and generates more economic loss.
Full text here: doi.org/10.1186/s101...
Compared with TTH, #migraine compromises brain health more severely and generates more economic loss.
Full text here: doi.org/10.1186/s101...
November 6, 2025 at 5:07 PM
How common chronic headache disorders are and how much productivity loss they are causing within administrative bodies?
Compared with TTH, #migraine compromises brain health more severely and generates more economic loss.
Full text here: doi.org/10.1186/s101...
Compared with TTH, #migraine compromises brain health more severely and generates more economic loss.
Full text here: doi.org/10.1186/s101...
The International Headache Society’s new position statement highlights the importance of early migraine prevention. It recommends considering preventive therapy from 2–4 monthly migraine days and underscores the need for studies to evaluate early intervention benefits: doi.org/10.1177/0333...
October 29, 2025 at 12:05 AM
The International Headache Society’s new position statement highlights the importance of early migraine prevention. It recommends considering preventive therapy from 2–4 monthly migraine days and underscores the need for studies to evaluate early intervention benefits: doi.org/10.1177/0333...
New meta-analysis found no clear link between migraine and overall, cardiovascular, or suicide-related mortality. Some studies identified a link between women with migraine aura and increased cardiovascular risk, highlighting the need for more research and sex-specific risks doi.org/10.1186/s101...
October 26, 2025 at 10:24 PM
New meta-analysis found no clear link between migraine and overall, cardiovascular, or suicide-related mortality. Some studies identified a link between women with migraine aura and increased cardiovascular risk, highlighting the need for more research and sex-specific risks doi.org/10.1186/s101...
Women with migraine show higher serum levels of CGRP, a key migraine-related molecule, compared to healthy controls. A CGRP level above 40 pg/mL was linked to more frequent attacks and greater pain sensitivity. Links between CGRP and rimegepant response were identified: doi.org/10.1186/s101...
October 23, 2025 at 1:05 PM
Women with migraine show higher serum levels of CGRP, a key migraine-related molecule, compared to healthy controls. A CGRP level above 40 pg/mL was linked to more frequent attacks and greater pain sensitivity. Links between CGRP and rimegepant response were identified: doi.org/10.1186/s101...
New study: Men with migraine are much less likely than women to get the right diagnosis before seeing a specialist (57% vs 74%). Women often show classic migraine signs, while men have less typical symptoms—leading to missed or delayed care. doi.org/10.1186/s101...
October 22, 2025 at 8:20 PM
New study: Men with migraine are much less likely than women to get the right diagnosis before seeing a specialist (57% vs 74%). Women often show classic migraine signs, while men have less typical symptoms—leading to missed or delayed care. doi.org/10.1186/s101...
🧠New insight into migraine and inflammation: results from a large systematic review and meta-analysis (57 studies, ~2 850 migraine patients) reveals that different inflammatory markers are associated with different migraine states.
doi.org/10.1186/s101...
doi.org/10.1186/s101...
October 19, 2025 at 11:25 AM
🧠New insight into migraine and inflammation: results from a large systematic review and meta-analysis (57 studies, ~2 850 migraine patients) reveals that different inflammatory markers are associated with different migraine states.
doi.org/10.1186/s101...
doi.org/10.1186/s101...
🧠 New research suggests a promising approach for post-traumatic headache (PTH) relief!
doi.org/10.1186/s101...
doi.org/10.1186/s101...
October 18, 2025 at 2:39 PM
🧠 New research suggests a promising approach for post-traumatic headache (PTH) relief!
doi.org/10.1186/s101...
doi.org/10.1186/s101...
This new meta-analysis reveals how the brain’s electrical activity changes across migraine phases in Hemiplegic migraine👇
⚡ Aura: 71% show low-amplitude EEG on the opposite side of paralysis
⚡ Headache/Post-headache: slowing in the same region
⚡ Interictal: 79% normal EEG
doi.org/10.1186/s101...
⚡ Aura: 71% show low-amplitude EEG on the opposite side of paralysis
⚡ Headache/Post-headache: slowing in the same region
⚡ Interictal: 79% normal EEG
doi.org/10.1186/s101...
October 17, 2025 at 5:28 PM
This new meta-analysis reveals how the brain’s electrical activity changes across migraine phases in Hemiplegic migraine👇
⚡ Aura: 71% show low-amplitude EEG on the opposite side of paralysis
⚡ Headache/Post-headache: slowing in the same region
⚡ Interictal: 79% normal EEG
doi.org/10.1186/s101...
⚡ Aura: 71% show low-amplitude EEG on the opposite side of paralysis
⚡ Headache/Post-headache: slowing in the same region
⚡ Interictal: 79% normal EEG
doi.org/10.1186/s101...
We have extended the late breaking abstract deadline to 10 October!
Whether you are working on innovative treatments, new clinical data, or emerging insights in headache and migraine research, we want to hear from you.
📢 Submit your abstract today: headache-congress.org/programme-ab...
#EHC25
Whether you are working on innovative treatments, new clinical data, or emerging insights in headache and migraine research, we want to hear from you.
📢 Submit your abstract today: headache-congress.org/programme-ab...
#EHC25
September 29, 2025 at 12:54 PM
We have extended the late breaking abstract deadline to 10 October!
Whether you are working on innovative treatments, new clinical data, or emerging insights in headache and migraine research, we want to hear from you.
📢 Submit your abstract today: headache-congress.org/programme-ab...
#EHC25
Whether you are working on innovative treatments, new clinical data, or emerging insights in headache and migraine research, we want to hear from you.
📢 Submit your abstract today: headache-congress.org/programme-ab...
#EHC25
Headaches are widespread but under-recognised in the German military: 95% had headaches last year, 27% migraine, 29% probable migraine. 64% lost workdays; migraineurs ~4 days/month. Most had no diagnosis & few used preventives. Better screening & care needed. Read more: doi.org/10.1177/0333...
September 24, 2025 at 2:13 PM
Headaches are widespread but under-recognised in the German military: 95% had headaches last year, 27% migraine, 29% probable migraine. 64% lost workdays; migraineurs ~4 days/month. Most had no diagnosis & few used preventives. Better screening & care needed. Read more: doi.org/10.1177/0333...
Spreading depolarization triggers migraine-like facial pain and anxiety in a model. Oral atogepant, a CGRP receptor blocker, reduces pain and eliminates grimace responses, while also improving anxiety-like behavior, highlighting its potential for migraine treatment. doi.org/10.1186/s101...
September 22, 2025 at 10:31 AM
Spreading depolarization triggers migraine-like facial pain and anxiety in a model. Oral atogepant, a CGRP receptor blocker, reduces pain and eliminates grimace responses, while also improving anxiety-like behavior, highlighting its potential for migraine treatment. doi.org/10.1186/s101...
New methods in awake models are improving our understanding of spreading depolarization, key in migraine with aura. Techniques like optogenetics, wireless telemetry, and two-photon imaging enable minimally invasive, long-term monitoring, bridging the gap to human studies. doi.org/10.1186/s101...
September 19, 2025 at 11:11 PM
New methods in awake models are improving our understanding of spreading depolarization, key in migraine with aura. Techniques like optogenetics, wireless telemetry, and two-photon imaging enable minimally invasive, long-term monitoring, bridging the gap to human studies. doi.org/10.1186/s101...
📢 Call for Papers – Journal of Headache and Pain
Submit your work to our new collections:
🧠 Pain in Neurodegenerative Diseases
🧬 Epigenome & Transcriptome in Headache
💊 Community Pharmacy & Headache Care
Help shape the future of headache research.
🔗 thejournalofheadacheandpain.biomedcentral.com
Submit your work to our new collections:
🧠 Pain in Neurodegenerative Diseases
🧬 Epigenome & Transcriptome in Headache
💊 Community Pharmacy & Headache Care
Help shape the future of headache research.
🔗 thejournalofheadacheandpain.biomedcentral.com
September 17, 2025 at 3:09 PM
📢 Call for Papers – Journal of Headache and Pain
Submit your work to our new collections:
🧠 Pain in Neurodegenerative Diseases
🧬 Epigenome & Transcriptome in Headache
💊 Community Pharmacy & Headache Care
Help shape the future of headache research.
🔗 thejournalofheadacheandpain.biomedcentral.com
Submit your work to our new collections:
🧠 Pain in Neurodegenerative Diseases
🧬 Epigenome & Transcriptome in Headache
💊 Community Pharmacy & Headache Care
Help shape the future of headache research.
🔗 thejournalofheadacheandpain.biomedcentral.com
Epigenetic changes in the RONS-TRPA1-CGRP pathway may shape migraine susceptibility, chronification, and treatment response. Insights from a narrative review.
doi.org/10.1186/s101...
doi.org/10.1186/s101...
September 11, 2025 at 7:27 AM
Epigenetic changes in the RONS-TRPA1-CGRP pathway may shape migraine susceptibility, chronification, and treatment response. Insights from a narrative review.
doi.org/10.1186/s101...
doi.org/10.1186/s101...
🔬 New Tool in Migraine Care: The “CGRP Score” Nomogram. This ML-based predictive score achieved a good performance in identifying responders to anti-CGRP mAbs. The nomogram has the potential to be a practical, user-friendly tool for supporting clinical decision-making.
doi.org/10.1186/s101...
doi.org/10.1186/s101...
September 11, 2025 at 7:22 AM
🔬 New Tool in Migraine Care: The “CGRP Score” Nomogram. This ML-based predictive score achieved a good performance in identifying responders to anti-CGRP mAbs. The nomogram has the potential to be a practical, user-friendly tool for supporting clinical decision-making.
doi.org/10.1186/s101...
doi.org/10.1186/s101...
🤖💡 AI is reshaping how we approach headache care. A systematic review of 76 studies highlights progress in diagnosis, treatment prediction, and digital health monitoring.
But major challenges remain. So, AI should augment—not replace—the doctor–patient relationship.
doi.org/10.1186/s101...
But major challenges remain. So, AI should augment—not replace—the doctor–patient relationship.
doi.org/10.1186/s101...
September 9, 2025 at 8:45 PM
🤖💡 AI is reshaping how we approach headache care. A systematic review of 76 studies highlights progress in diagnosis, treatment prediction, and digital health monitoring.
But major challenges remain. So, AI should augment—not replace—the doctor–patient relationship.
doi.org/10.1186/s101...
But major challenges remain. So, AI should augment—not replace—the doctor–patient relationship.
doi.org/10.1186/s101...
This year’s programme features high-level plenaries, cutting-edge debate sessions, interactive teaching courses, and forward-looking updates – all under the theme “Transforming Challenges into Solutions”.
September 4, 2025 at 6:55 AM
This year’s programme features high-level plenaries, cutting-edge debate sessions, interactive teaching courses, and forward-looking updates – all under the theme “Transforming Challenges into Solutions”.
Late breaking abstracts are open – perfect for those last-minute discoveries!
You have groundbreaking results or fresh insights to share? Submit your late breaking abstract now & showcase your latest research to a global audience.
🗓️ Deadline: 29 September 2025
🔗 headache-congress.org/programme-ab...
You have groundbreaking results or fresh insights to share? Submit your late breaking abstract now & showcase your latest research to a global audience.
🗓️ Deadline: 29 September 2025
🔗 headache-congress.org/programme-ab...
August 29, 2025 at 6:28 AM
Late breaking abstracts are open – perfect for those last-minute discoveries!
You have groundbreaking results or fresh insights to share? Submit your late breaking abstract now & showcase your latest research to a global audience.
🗓️ Deadline: 29 September 2025
🔗 headache-congress.org/programme-ab...
You have groundbreaking results or fresh insights to share? Submit your late breaking abstract now & showcase your latest research to a global audience.
🗓️ Deadline: 29 September 2025
🔗 headache-congress.org/programme-ab...
Established molecular triggers reliably induce extracerebral arterial dilation, an effect reversed by sumatriptan. These findings support the hypothesis that sustained meningeal vasodilation might contribute causally to #migraine pathogenesis.
Read more here: rdcu.be/eCJA3
Read more here: rdcu.be/eCJA3
August 27, 2025 at 4:01 PM
Established molecular triggers reliably induce extracerebral arterial dilation, an effect reversed by sumatriptan. These findings support the hypothesis that sustained meningeal vasodilation might contribute causally to #migraine pathogenesis.
Read more here: rdcu.be/eCJA3
Read more here: rdcu.be/eCJA3
Longitudinal assessment of #migraine burden in resistant and refractory migraine – Data from the prospective REFINE study.
While both ResM and RefM reflect high migraine disability burden, they might present relevant differences in their management and prognosis.
rdcu.be/eB8lD
While both ResM and RefM reflect high migraine disability burden, they might present relevant differences in their management and prognosis.
rdcu.be/eB8lD
August 24, 2025 at 11:30 AM
Longitudinal assessment of #migraine burden in resistant and refractory migraine – Data from the prospective REFINE study.
While both ResM and RefM reflect high migraine disability burden, they might present relevant differences in their management and prognosis.
rdcu.be/eB8lD
While both ResM and RefM reflect high migraine disability burden, they might present relevant differences in their management and prognosis.
rdcu.be/eB8lD
Trigeminal neuralgia affects brain-wide networks—not just facial pain areas. Patients show reduced brain flexibility and control, especially with age. Evidence suggests it is a whole-network disorder, not a local one. Read the article: doi.org/10.1186/s101...
August 17, 2025 at 9:17 PM
Trigeminal neuralgia affects brain-wide networks—not just facial pain areas. Patients show reduced brain flexibility and control, especially with age. Evidence suggests it is a whole-network disorder, not a local one. Read the article: doi.org/10.1186/s101...