David Ashbrook
davidashbrook.bsky.social
David Ashbrook
@davidashbrook.bsky.social
Baszucki Foundation Chancellor’s Fellow @edinburgh-uni.bsky.social
Associate Professor in Genetics, Genomics, and Informatics @UTHSC

Genomes, environments, their interactions, behaviour and disease.

PhD Manchester 🇬🇧 Postdoc Toronto 🇨🇦 Associate Prof TN
Reposted by David Ashbrook
We are opening a FACULTY POSITION (tenure track, permanent) in the University of Cambridge at the interface of control and biology, interpreted broadly. Theorists and wet lab quantitative biologists with backgrounds in control, EE, applied math, ... apply by Jan 28!

www.cam.ac.uk/jobs/univers...
University Assistant/Associate Professor in Control Theory and Systems Biology
Applications are invited for a University Assistant/Associate Professorship in the broad area of Control Theory and Systems Biology. The successful candidate will join the Control Group
www.cam.ac.uk
December 3, 2025 at 12:19 PM
Reposted by David Ashbrook
High-quality mouse reference genomes [PacBio Long Read genomes of 17 strains] reveal the structural complexity of the murine protein-coding landscape, Cell Genomics. www.cell.com/cell-genomic... Genomes and annotations here: projects.ensembl.org/mouse_genomes/
High-quality mouse reference genomes reveal the structural complexity of the murine protein-coding landscape
Helmy et al. provide a collection of high-quality mouse reference genomes. They were able to resolve some of the most complex regions among mouse genomes that are involved in immune defense. These fin...
www.cell.com
December 2, 2025 at 4:30 AM
Reposted by David Ashbrook
"I am *unsettled* that ChatGPT, fed on the plethora of articles I and others have written on the subject as well as my own chat history has reproduced a rough sketch of our arguments back to me, this is *chilling*!"

This guy has massive influence on tech policy. Wonderful.
December 2, 2025 at 3:13 AM
Reposted by David Ashbrook
Haidt is "stunned" that ChatGPT asked how it would threaten youth reveals that its plan would be what Haidt has argued in his books. The secret plan!

There should be some way to rescind the doctorate of any commentator on digital media who interprets ChatGPT output like this. I am not joking.
December 2, 2025 at 3:07 AM
Reposted by David Ashbrook
Dr. Hayley Thorpe explores the intersection of complex traits with mental health using translational population genetics approaches #ACNP2026

Her recent work uses new GWAS of cannabis use traits to understand cannabis use genetic & biological underpinnings: tinyurl.com/57vdj3df
December 1, 2025 at 6:01 PM
Reposted by David Ashbrook
Another great preprint on neuronal APOE4 from the Huang lab!
Neuronal APOE4 alone is sufficient to drive tau pathology, neurodegeneration, and neuroinflammation in an Alzheimer's disease mouse model https://www.biorxiv.org/content/10.1101/2025.11.25.690488v1
November 29, 2025 at 5:27 PM
Reposted by David Ashbrook
i can not be the only person wondering about the five percent gap between bigfoot and the yeti
i mean is this where u draw the line
New polling on aliens
% of U.S. adult citizens who believe the following definitely or probably exist:
Aliens 56%
Bigfoot 28%
The Yeti 23%
The Loch Ness Monster 22%
Chupacabra 16%
today.yougov.com/health/artic...
November 25, 2025 at 11:37 PM
Reposted by David Ashbrook
We are excited to share our online book and preprint on “Orchestrating Spatial Transcriptomics Analysis with Bioconductor”!
Many people hours, calls and messages later: OSTA is now “in (pre)print”, though the real thing lives at bioconductor.org/books/OSTA.

Check it out, get in touch. We welcome any feedback, suggestions, wishes (& contributions).

It’s been a joy working with you @estellayixingdong.bsky.social!
November 22, 2025 at 12:38 PM
Reposted by David Ashbrook
Google at its peak was basically the best information retrieval system in human history and they and every competitor decided going from there to “you didn’t want answers you wanted half-assed auto-complete 80%-wrong hallucinations” in a few years was the right idea
November 25, 2025 at 1:57 AM
Reposted by David Ashbrook
We (Nordborg & Weigel labs) need input on the next generation of genome browsers & data download modes for the #Arabidopsis #1001GenomesPlus project. We have now a curated collection of over 500 long read genomes.

Please help us by filling out this questionnaire: docs.google.com/forms/d/e/1F...
Next generation of 1001 Genomes Plus browser and data download
Please indicate all features you would like to see in a browser that displays features of completely sequenced Arabidopsis thaliana genomes
docs.google.com
November 24, 2025 at 2:49 PM
Reposted by David Ashbrook
Is "top-notch" the new "highly motivated"?
November 23, 2025 at 1:19 PM
Reposted by David Ashbrook
We are co-funding a new clinical trial to investigate if a one-off gene therapy to replace faulty genes in stem cells can bring hope to children with Hunter syndrome.

Ollie is the first child to participate in this @manchester.ac.uk study: bit.ly/49BaCjt
Hunter syndrome: Boy with rare condition amazes doctors after world-first gene therapy
Oliver has an inherited condition called Hunter syndrome, which causes progressive damage to the body and brain.
bit.ly
November 24, 2025 at 9:15 AM
Reposted by David Ashbrook
We are recruiting - deadline approaching!!! Postdoc position available in my lab to develop an exciting project with @alexfsantos2401.bsky.social to advance our understanding of food allergy and oral tolerance in early life.
#ILC #organoids #intestine #FoodAllergy

www.kcl.ac.uk/jobs/128585-...
November 24, 2025 at 8:40 AM
Reposted by David Ashbrook
This week, I withdrew from a speaking engagement at a public university because they sent me a list of prohibited “words & concepts.” I will not humor this censorship. It does a disservice to the stories I’m discussing & the audience, who deserve unfettered access to information & conversation.
November 20, 2025 at 10:20 PM
Reposted by David Ashbrook
Our lab digs into how serotonin tunes prediction errors and eye movements — with custom tools and curious mice.We got 2 posters at #SfN2025, Tue AM (C5) and Wed PM (R16).
Recruiting PhD students & postdocs in sunny Marseille.
Come chat about neuromodulators, tinkering, or free will and intuition.
November 18, 2025 at 1:16 AM
Reposted by David Ashbrook
To study how animals understand the physical world (and the rules that govern its dynamics), @jinyao-y.bsky.social trains rats to play fetch with robots 🐀🤖🎾

To learn more, come to our poster Tuesday morning!
[Board W11] Rats learn and use intuitive physics knowledge to solve fetch tasks.
#SfN2025
November 18, 2025 at 1:16 AM
Reposted by David Ashbrook
Had a great time presenting one of my PhD rotation projects in the @bjmarlin lab - a project that holds a special place in my heart! 👩🏻‍🔬💕🧠💗 #SfN #SfN25
November 18, 2025 at 7:11 AM
Reposted by David Ashbrook
There’s still time to connect with Isabelle Aiken and Frederic Gagnon at #SfN25!
If you missed the poster presentation on “𝗔𝗱𝘃𝗮𝗻𝗰𝗲𝗱 𝗘𝗘𝗚 𝗧𝗲𝗹𝗲𝗺𝗲𝘁𝗿𝘆 𝗠𝗲𝗮𝘀𝘂𝗿𝗲𝗺𝗲𝗻𝘁𝘀 𝗶𝗻 𝗠𝗶𝗰𝗲” (in collaboration with Porsolt), visit us at booth #2130 or download it here:
hubs.ly/Q03Txd5Z0
Advanced EEG Telemetry Measurements in Mice
Presented at SFN 2025: 𝗔𝗱𝘃𝗮𝗻𝗰𝗲𝗱 𝗘𝗘𝗚 𝗧𝗲𝗹𝗲𝗺𝗲𝘁𝗿𝘆 𝗠𝗲𝗮𝘀𝘂𝗿𝗲𝗺𝗲𝗻𝘁𝘀 𝗶𝗻 𝗠𝗶𝗰𝗲: 𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀 𝗳𝗼𝗿 𝗦𝗲𝗶𝘇𝘂𝗿𝗲 𝗣𝗵𝗲𝗻𝗼𝘁𝘆𝗽𝗶𝗻𝗴, 𝗤𝘂𝗮𝗻𝘁𝗶𝘁𝗮𝘁𝗶𝘃𝗲 𝗘𝗘𝗚, 𝗮𝗻𝗱 𝗦𝗹𝗲𝗲𝗽 𝗔𝗿𝗰𝗵𝗶𝘁𝗲𝗰𝘁𝘂𝗿𝗲
hubs.ly
November 18, 2025 at 7:55 AM
Reposted by David Ashbrook
@sfn.org #SfN2025 Interested in continuing your career in Germany? Come by the #NeuroscienceinGermany booth 3917 and meet scientists and funding agencies that can help you achieve your goals! 👇 🧠 🇩🇪
November 17, 2025 at 5:45 PM
Reposted by David Ashbrook
If you are at #sfn25 and work with animals in your #neuroscience research: drop by booth 3600, the Global Consortium for Public Outreach on Animal Research
November 17, 2025 at 3:55 PM
Reposted by David Ashbrook
#SfN25 Mini-symposium: Today at 9:30 am PST | The Richness of Vision in the Mammalian Brain: Neural Codes for Visual Perception and Behavior in Three Dimensions
Read the accompanying article by Rosenberg et al. in #JNeurosci
https://doi.org/10.1523/JNEUROSCI.1316-25.2025
November 17, 2025 at 4:00 PM
Reposted by David Ashbrook
Get career advice from the pros!

Early-career scientists can connect with experienced to discuss training, career development, and more at #SfN25 Ask Anything sessions.

Add a session to your itinerary.

🔗 vist.ly/4evd2
Get career advice from the pros! Early-career scientists can connect with experienced to discuss training, career development, and more at #SfN25 Ask Anything sessions. Add a session to your itinerary. 🔗 vist.ly/4evd2
Get career advice from the pros! Early-career scientists can connect with experienced to discuss training, career development, and more at #SfN25 Ask Anything sessions. Add a session to your itinerary. 🔗 vist.ly/4evd2
www.abstractsonline.com
November 17, 2025 at 6:30 PM
Reposted by David Ashbrook
There's 2 amazing Fonken Lab postbacs presenting this afternoon too:

C13: Em Anders - effects of early life hormonal manipulation on microglia in rats.

C24: Cecily Gibson - impact of circadian rhythm disruption on maternal caregiving & microglia in mice.

#SocietyForGlia #SfN25 #SfN2025
November 17, 2025 at 8:22 PM
Reposted by David Ashbrook
#SfN25 's hottest club is Poster X8 Tuesday Morning. This club has everything: mice hunting robotic bait, quantitative behavior modeling, chronic superior colliculus Neuropixel data, and GLM encoding/decoding, not to mention the cheap new DAQ EVERYONE's been rumbling about. See you there!
November 17, 2025 at 9:37 PM
Reposted by David Ashbrook
I'm not at #Sfn25 this year and I'm having #SfNswag FOMO. Please fill me in!! (My recap video from last year's day 1 haul vm.tiktok.com/ZNdojN3re/)
TikTok - Make Your Day
vm.tiktok.com
November 17, 2025 at 10:07 PM