@audreygasch.bsky.social
Our paper is out studying premature aging (a hallmark of Down syndrome) in aneuploid yeast. Who knew part of the problem is in Ribosome Quality Control. Congrats to Leah Escalante for leading this tour de force.
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Chromosome duplication causes premature aging via defects in ribosome quality control
Syndromes caused by chromosome amplification, such as Down syndrome, are characterized by premature aging, but the reason behind this is unclear. This study shows that chromosome amplification in yeas...
journals.plos.org
December 5, 2025 at 4:58 PM
Our paper is out studying premature aging (a hallmark of Down syndrome) in aneuploid yeast. Who knew part of the problem is in Ribosome Quality Control. Congrats to Leah Escalante for leading this tour de force.
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...