UW News
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Experts, research and administration news from the University of Washington. Media assistance: [email protected].
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Our new paper entitled “Boolean Logic-gated Protein Presentation through Autonomously Compiled Molecular Topology” is now live at Nature Chemical Biology (@natchembio.nature.com)! Check it out!

📜: www.nature.com/articles/s41...

@uwnews.uw.edu feature write-up: www.washington.edu/news/2025/10...
Stimulus-responsive materials have enabled advanced applications in biosensing, tissue engineering and therapeutic delivery. Although controlled molecular topology has been demonstrated as an effective route toward creating materials that respond to prespecified input combinations, prior efforts suffer from a reliance on complicated and low-yielding multistep organic syntheses that dramatically limit their utility. Harnessing the power of recombinant expression, we integrate emerging chemical biology tools to create topologically specified protein cargos that can be site-specifically tethered to and conditionally released from biomaterials following user-programmable Boolean logic. Critically, construct topology is autonomously compiled during expression through spontaneous intramolecular ligations, enabling direct and scalable synthesis of advanced operators. Using this framework, we specify protein release from biomaterials following all 17 possible YES/OR/AND logic outputs from input combinations of three orthogonal protease actuators, multiplexed delivery of three distinct biomacromolecules from hydrogels, five-input-based conditional cargo liberation and logically defined protein localization on or within living mammalian cells.
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Research by the University of Washington and the USPTO found that some simple interventions increased the probability that female inventors would get patents by 12%. For first-time applicants, that probability increased to 17%.
A simple intervention significantly improved patent outcomes for women inventors
Research by the University of Washington and the USPTO found that some simple interventions increased the probability that female inventors would get patents by 12%. For first-time applicants, that...
www.washington.edu
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Analysis of data from the Cassini space probe has identified organic compounds within jets of water ice erupting from Saturn’s moon Enceladus. Some of the compounds have never before been identified on another world beyond Earth.
More: www.washington.edu/news/2025/10...
Light rises over a planet A ring of light in space An icy planet
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UW alum Mary Brunkow, ’83, won the Nobel Prize in Medicine this morning.
This photo was taken while she was on the phone with the Nobel Committee in Sweden. Mary said she initially missed the call because a strange number popped up on her phone — she thought it might be spam.
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Quantum dots, which are 10,000 times smaller than the width of a human hair, are unique materials that generate very specific colors of light. Researchers, including @brandicossairt.bsky.social, hope that quantum dots can one day be useful for more than just illuminating TV screens.
Q&A: From TVs to the future of computing, UW professor explains what makes quantum dots shine
Quantum dots, which are 10,000 times smaller than the width of a human hair, are unique materials that generate very specific colors of light. Researchers, including Brandi Cossairt, UW professor of...
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Bee experts wouldn’t have previously expected to find the likes of Osmia cyaneonitens, Dufourea dilatipes and Stelis heronae in Washington. But this year, researchers added eight new bee species to a list of the state’s native pollinators.
More: www.washington.edu/news/2025/09...
Close-up of a bee specimen pinned for display. Overhead macro shot of a bee. A collection of pinned insect specimens.
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Long baleen whale mothers are more likely to have female calves than males, according to a new study led by the University of Washington. The findings contradict a popular evolutionary theory postulating that strong mammals benefit more from birthing males.
More: www.washington.edu/news/2025/09...
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From the dense ring of dust that surrounds the Butterfly Nebula’s core to the tiny but bright star hidden within, observations from the James Webb Space Telescope paint a never-before-seen portrait of the nebula’s inner workings.
More: www.washington.edu/news/2025/09...
A colorful, swirling nebula A cosmic butterfly with red and blue wings A vibrant, symmetrical space image from Hubble, resembling a butterfly.
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Welcome back to class today, Huskies!
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uwdeohs.bsky.social
Join us Oct. 16! Jordan Barab, former deputy assistant secretary for the Occupational Safety & Health Administration (OSHA), will deliver the Breysse Lecture on "Workplace Safety and Health in the Current Political Landscape.” Get a sneak peek on our blog:
deohs.washington.edu/hsm-blog/how...
How politics influence workplace health and safety
Jordan Barab, former deputy assistant secretary for US Occupational Safety and Health Administration, presents Breysse Lecture on October 16
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Welcome, Huskies! Thousands of incoming @uofwa.bsky.social students gathered for an annual 'W' formation today after kicking off the school year with a convocation ceremony. #newhuskies2025 #uwdawgdaze
Media assets: drive.google.com/drive/folder...
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Dengue fever incidence could rise as much as 76% by 2050 in parts of the world, according to a new @uwdeohs.bsky.social study.
More: www.washington.edu/news/2025/09...
A person sprays to keep bugs away
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Sven Haakanson, a UW professor of anthropology, worked with three Coast Salish carvers to install a story pole on campus. Story poles are created to share and teach Coast Salish legends, histories and stories. A celebration will be held by the carvers on Thursday.
www.washington.edu/news/2025/09...
A person carves on a wood pole. A person carves on a wood pole. A person carves on a wood pole. A person carves on a wood pole.
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Welcome home, Huskies! Students living on campus are moving in beginning today. B-roll and soundbites are available for media: drive.google.com/drive/folder...