UCI Center for the Study of Cannabis
@ucicannabis.bsky.social
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University of California Irvine School of Medicine's Center for the Study of Cannabis: https://cannabis.uci.edu/
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🌟 UCI ICAL is back!
We’re proud to relaunch the UCI Interdisciplinary Center for the Study of Cannabis & Cannabinoids—a NIDA Center of Excellence advancing #cannabisresearch.
Follow us for updates! 🌱🔬
👉 IG: @uci_cannabis
👉 X: @ucicannabis
👉 BlueSky: @ucicannabis.bsky.social
ucicannabis.bsky.social
🧠 THC researchers: Get free adolescent THC brain & organ tissue from UCI ICAL Tissue Bank! No DEA license needed, shipping covered. Limited supply—first-come, first-served! 🌱🔬
📩 DM for info
IG: @uci_cannabis | X: @ucicannabis

REQUEST HERE: cannabis.uci.edu/ical/tissueb...

#CannabisResearch #THC
ICAL Tissue Bank - UCI Center for the Study of Cannabis
ICAL Tissue Bank ICAL maintains a biobank of brain and peripheral organs collected from mice and rats treated in adolescence with D9-tetrahydrocannabinol (THC) or vehicle. Both male and female…
cannabis.uci.edu
ucicannabis.bsky.social
In case you missed it from ICAL: New publication! Protocol for administering Δ9-THC in adolescent & adult mice, showing effects on catalepsy, locomotion, and pain — with safe, legal handling tips. 🔬💊

Link here: app.jove.com/t/68358/admi...
ucicannabis.bsky.social
🎙️ New Science at the Source!

Dr. Hilary Marusak + Rodrigo M. Klein, PhD (UC Irvine) on how THC impacts the developing brain.

🧠 Resilience & risk
👩🔬 Microglia & endocannabinoid system
🌍 Context & cannabis use

👉 Watch: www.youtube.com/watch?v=oap6...
ucicannabis.bsky.social
📢 Cannabis researchers: UCI ICAL Tissue Bank 🧠🫀
Brain & organs from THC/vehicle-treated mice/rats, prepped for molecular studies. FREE, shipping included, no DEA needed. ⚠️ First-come, first-served!
cannabis.uci.edu/ical/tissueb...
ucicannabis.bsky.social
🚨 New Science at the Source!

Dr. Hilary Marusak talks with Dr. Christine Gall (UC Irvine) on how adolescent THC impacts memory, sex differences, and brain health.

🎥 youtu.be/iBdVUbXZNOA

#THC #AdolescentBrain #Memory #ScienceAtTheSource
ucicannabis.bsky.social
🚨 Still thinking about this convo with Maricela Martinez.

What if the key to understanding addiction risk lies in the brain’s immune cells?
Episode 6 of Science at the Source dives into microglia, adolescence, and how early drug exposure may prime the brain.

🎥 youtu.be/RO_g9KTaMCA

#Microglia #THC
THC Exposure and Metabolic Health with Dr. Kwang-Mook Jung | Science at the Source Ep. 3
Welcome to another enlightening episode of Science at the Source! In this episode, Dr. Hilary Marusak engages with Dr. Kwang-Mook Jung, a pioneering researcher exploring the intersection of…
youtu.be
ucicannabis.bsky.social
🚨 Save the Date! 🚨
The MACRC 2025 Conference — the first official ICRS Chapter meeting 🍃
📅 Nov 14–16, 2025 | 📍 Kitty Hawk, NC
Abstracts & registration open (early bird thru Sept 21)!
👉 www.m-acrc.org

#CannabinoidResearch #MACRC2025 #ICRS
ucicannabis.bsky.social
🚨 Rewind to Science at the Source Ep. 5
Dr. Steve Mahler breaks down the neuroscience of craving, THC, and motivation—and what it means for cannabis use and addiction treatment. Still thinking about this one.
🎥 www.youtube.com/watch?v=9ImB...
IG → @uci_cannabis #CannabisResearch #MotivationAndReward
Exploring Motivation, Cannabinoids, and the Brain with Dr. Steve Mahler| Science at the Source Ep. 5
Welcome back to Science at the Source! 🎙️ In this episode, we sit down with Dr. Steve Mahler, neuroscientist and Professor at UC Irvine, to explore how the brain’s motivation and reward systems are…
www.youtube.com
ucicannabis.bsky.social
🚨 Cannabis researchers: Need THC-exposed brain or organ samples? 🧠🫀

The UCI ICAL Tissue Bank offers FREE tissues (U.S. & abroad), no DEA license needed.
Brain tissue = high demand—act fast! 📩

🔗 cannabis.uci.edu/ical/tissueb...

@uci_cannabis #CannabisResearch #THCResearch
ICAL Tissue Bank - UCI Center for the Study of Cannabis
ICAL Tissue Bank ICAL maintains a biobank of brain and peripheral organs collected from mice and rats treated in adolescence with D9-tetrahydrocannabinol (THC) or vehicle. Both male and female…
cannabis.uci.edu
ucicannabis.bsky.social
🧪 New ICAL protocol paper: Standardized methods for administering THC to adolescent & adult mice.

Includes prep, legal compliance, and key readouts: catalepsy, locomotion, nociception.
🔗 app.jove.com/t/68358

🧠 Essential for modeling developmental effects of cannabis.
#THC #CannabisResearch #ICAL
ucicannabis.bsky.social
🚨 Vaping THC ≠ smoking it.

In Science at the Source Ep. 4, Dr. Alexa Torrens breaks down how vaping affects the teen brain—& why the nose matters more than you think.

Watch: www.youtube.com/watch?v=D9hc...
Follow → @uci_cannabis

#CannabisResearch #THCVaping #AdolescentBrain #ScienceAtTheSource
ucicannabis.bsky.social
🎙️ Revisit this must-hear convo! Dr. Hilary Marusak talks with Dr. Kwang-Mook Jung about adolescent THC exposure & long-term metabolic health.

🔥 Why are cannabis users leaner?
🧬 How THC alters fat & energy use?
🌿 Endocannabinoid insights await.

🎧 youtu.be/RO_g9KTaMCA
#ScienceAtTheSource #THC
ucicannabis.bsky.social
🚨 Researchers! Free brain & peripheral tissues from adolescent THC-exposed rodents via the ICAL Tissue Bank at UCI.

✅ No DEA license needed
✅ Great for pilot data & grants
🌍 Open globally (shipping not covered)

Apply early—high demand!
🔗 cannabis.uci.edu/ical/tissueb...
#CannabisResearch #THC
ICAL Tissue Bank - UCI Center for the Study of Cannabis
ICAL Tissue Bank ICAL maintains a biobank of brain and peripheral organs collected from mice and rats treated in adolescence with D9-tetrahydrocannabinol (THC) or vehicle. Both male and female…
cannabis.uci.edu
ucicannabis.bsky.social
🌿 Re-sharing this fascinating episode!
Is cannabis a psychedelic?

Dr. Daniele Piomelli explores this question in a 20-minute lecture from our Science at the Source series.

Watch (or re-watch) now ➡️ youtu.be/G0tagjX8COw

#CannabisResearch #Psychedelics #Neuroscience #ICAL
ucicannabis.bsky.social
🌿 How does cannabis impact the brain across the lifespan?

🎥 Check out Science at the Source from UC Irvine’s ICAL.
Dr. Daniele Piomelli breaks it down.

👉 Watch: youtu.be/Px45H-wuROA

Follow: @uci_cannabis

#CannabisResearch #ICAL #ScienceAtTheSource
ucicannabis.bsky.social
🚨 Researchers! Access FREE brain & organ tissues from adolescent THC-exposed rodents via the ICAL Tissue Bank @ UCI. No DEA license needed. Great for pilot data & grant apps. Apply now—brain tissues go fast! 📦 cannabis.uci.edu/ical/tissueb... #CannabisResearch #THC
ucicannabis.bsky.social
🧠 FAAH inhibitors may offer a new path for PTSD treatment. A 2023 preclinical study from ICAL shows that boosting endocannabinoid signaling with novel FAAH blockers (ARN14633 & ARN14280) ⬇️ anxiety-like behavior in rats exposed to predator stress. No major side effects.
🔗 doi.org/10.1007/s002...
ucicannabis.bsky.social
🧬 Recent ICAL study: THC reduces pain in a humanized mouse model of sickle cell disease.
Acute THC eased mechanical + cold hypersensitivity without affecting memory or anxiety.
Chronic use helped too—but tolerance emerged.
🔗 doi.org/10.1124/jpet...
#SCD #CannabisResearch #THC #PainScience #ICAL #UCI
ucicannabis.bsky.social
🧬 New ICAL study: Adolescent THC exposure in male mice led to lower sperm count, testicular damage, and hormone disruption—effects not seen with adult exposure. Adolescence may be a critical window of vulnerability.

📄 doi.org/10.1093/toxs...
#CannabisResearch #ReproductiveHealth #THC #Adolescent
doi.org
ucicannabis.bsky.social
🎙️ New ep!
Microglia, addiction, & early career science w/ Maricela Martinez (@ucirvine PhD student)

🧠 Brain-immune circuits in adolescence
🌿 How THC, nicotine, opioids affect microglia
🔁 Can we reset drug-altered brain immunity?

🎧 Listen: www.youtube.com/watch?v=koYL...
#Neuroimmunology
ucicannabis.bsky.social
🎙️ New Science at the Source episode!

Dr. Hilary Marusak talks with Dr. Steve Mahler (UC Irvine) about THC, craving, and the brain’s reward systems. 🎧 Don’t miss this deep dive into addiction + cannabis research.

🔗 www.youtube.com/watch?v=9ImB...
@uci_cannabis #Neuroscience #THC
ucicannabis.bsky.social
🚨 WE’RE MOVING! 🚨
Stay connected with the UCI Center for the Study of Cannabis 🌿🧠
Follow us for updates, research, and events:

📸 Instagram: @uci_cannabis
🌤️ Bluesky: @UCICANNABIS
▶️ YouTube: @ucicenterforthestudyofcann5100
💼 LinkedIn: @UCICANNABIS

🔍 Follow us and stay tuned!
ucicannabis.bsky.social
🧠 New from ICAL: Microglia & Addiction Risk

ICYMI—Drs. Martinez & Mahler explore how adolescent drug use may alter microglial function + raise long-term addiction risk.

📖: www.sciencedirect.com/science/arti...
🎙️ Author interview coming soon!
📲 IG: @uci_cannabis | BlueSky: @ucicannabis.bsky.social
ucicannabis.bsky.social
🚨 YouTube Talk
Can cannabis help manage chronic pain? 🌿🧠
Dr. Daniele Piomelli (UCI) explains how THC interacts with cannabinoid receptors to relieve pain.
🔥 Topics:
✅ How THC eases pain
✅ Cannabinoid receptors
✅ Scientific evidence + mechanisms

📺: www.youtube.com/watch?v=A7T1...
ucicannabis.bsky.social
⭐ There is still time to register⭐

The International Cannabinoid Research Society (ICRS) will host its 35th annual Symposium from July 6-10, 2025 – in Bloomington, Indiana.

Don't miss it!

Learn more and register: www.icrs.com/2025-symposium