Sam Stephens IA
@stephenslab.bsky.social
30 followers 25 following 5 posts
Scientist, beta-cell biologist at U Iowa FOE Diabetes Center https://stephens.lab.uiowa.edu/
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stephenslab.bsky.social
I do. I think there are significant modifications to the cell surface previously unrecognized. Hard to be certain where this would lead but I feel it’s start of a new direction with exciting possibilities
stephenslab.bsky.social
Excited to share a new study from the lab published in Diabetes. This was amazing work performed by Sandra Blom!

"Proinflammatory Cytokines Mediate Pancreatic β-Cell–Specific Alterations to Golgi Integrity via iNOS-Dependent Mitochondrial Inhibition"

doi.org/10.2337/db25...
Proinflammatory Cytokines Mediate Pancreatic β-Cell–Specific Alterations to Golgi Integrity via iNOS-Dependent Mitochondrial Inhibition
Type 1 diabetes (T1D) is caused by the selective autoimmune ablation of pancreatic β-cells. Emerging evidence reveals β-cell secretory dysfunction arises e
doi.org
stephenslab.bsky.social
Olof is a great host! Enjoy
stephenslab.bsky.social
Thanks to Matt Merrins for helping us upgrade our microscope for perifusion studies @merrinslab.bsky.social
stephenslab.bsky.social
Check out our recent review describing the bidirectional regulation between the ER and mitochondria
www.mdpi.com/3216548