Lightnews — Scholar-powered news

Reposted by Society for Mucosal Immunology

Mucosal Immunology @mucosalimmunol.bsky.social · 1d

The October Issue is now live! Featuring “Innate immunity of the gut epithelium: Blowing in the WNT?” www.mucosalimmunology.org/current

2 3

Reposted by Society for Mucosal Immunology

Mucosal Immunology @mucosalimmunol.bsky.social · 2h

Group 3 innate lymphoid cell-derived CSF2 tunes homeostasis of tissue macrophages and neutrophils from @sltai.bsky.social @theonlylabever.bsky.social and colleagues: www.mucosalimmunology.org/article/S193...

Group 3 innate lymphoid cell-derived CSF2 tunes homeostasis of tissue macrophages and neutrophils

Mucosal surfaces are complex ecosystems that rely on continuous communication between host and the inhabiting microbiota to sustain immune balance and health. The vast complexity of microbial communit...

www.mucosalimmunology.org

3 4

Society for Mucosal Immunology @societymucosalimm.bsky.social · 2h

Read the latest #SMIMemberPaper by Ludvig Sollid and colleagues in JCI on how interferon gamma promotes hyperplasia in intestinal crypts in #Celiac. Read more -> www.jci.org/articles/vie...

1

Society for Mucosal Immunology @societymucosalimm.bsky.social · 5d

SMI member Valerie Abadie reviews gut mucosal immune responses and their implications for celiac disease and food allergy at Seminars in Immunology: www.sciencedirect.com/science/arti...

#SMIMemberPaper #MucosalImmunology #Immunology

Gut mucosal immune responses – Implications for celiac disease and food allergy

The intestinal mucosa employs a diverse set of defense mechanisms—from mucosal barrier regulation to immunoregulatory pathways—to maintain homeostasis…

www.sciencedirect.com

1 4

Society for Mucosal Immunology @societymucosalimm.bsky.social · 7d

SMI Member Eduardo Villablanca and colleagues review B cells in inflammatory bowel disease at Immunology Letters:
www.sciencedirect.com/science/arti...

#SMIMemberPaper #MucosalImmunology #Immunology

3 6

Reposted by Society for Mucosal Immunology

Mucosal Immunology @mucosalimmunol.bsky.social · 10d

Novel loss-of-function intronic mutation in ELF4 is associated with intestinal autoinflammation www.mucosalimmunology.org/article/S193...

1 3

Society for Mucosal Immunology @societymucosalimm.bsky.social · 12d

SMI member De’Broski R Herbert and colleagues show TRPV1+ neurons promote cutaneous immunity against Schistosoma mansoni in this work from the Journal of Immunology:
academic.oup.com/jimmunol/adv...

#SMIMemberPaper

1

Reposted by Society for Mucosal Immunology

dshb-antibodies.bsky.social @dshb-antibodies.bsky.social · 26d

🔎 Spotted in @mucosalimmunol.bsky.social!
Researchers from #TongjiUniversity used DSHB's anti-dlg1 [4F3] mAb in a study on how bacterial membrane vesicles suppress CREB to regulate host immunity.

📄 tinyurl.com/yc7f97wk

🧫 dshb.biology.uiowa.edu/4F3-anti-dis...

1 4 3

Reposted by Society for Mucosal Immunology

Mucosal Immunology @mucosalimmunol.bsky.social · 19d

Akkermansia muciniphila ameliorates Salmonella-induced colitis and intestinal fibrosis
www.mucosalimmunology.org/article/S193...

Akkermansia muciniphila ameliorates Salmonella-induced colitis and intestinal fibrosis

Salmonella enterica serovar Typhimurium is a food-borne pathogen and a major cause of gastroenteritis in humans. The intestinal microbiota provides colonization resistance to enteric pathogens such as...

www.mucosalimmunology.org

1 3

Reposted by Society for Mucosal Immunology

Mucosal Immunology @mucosalimmunol.bsky.social · 18d

Innate immunity of the lungs in homeostasis and disease www.mucosalimmunology.org/article/S193...

3 5

Reposted by Society for Mucosal Immunology

Mucosal Immunology @mucosalimmunol.bsky.social · 14d

Check out our latest special collection on Skin Immunity: www.mucosalimmunology.org/mucimm-skin-...

2 4

Reposted by Society for Mucosal Immunology

Mucosal Immunology @mucosalimmunol.bsky.social · 13d

Common colds can exacerbate asthma symptoms. Research here connects Rhinovirus C15 infection to airway epithelial cell remodeling and robust inflammatory responses: www.mucosalimmunology.org/article/S193...

1 3 8

Society for Mucosal Immunology @societymucosalimm.bsky.social · 14d

SMI Member Martin Prlic discusses recent publications in "Six degrees of TGFβ" www.nature.com/articles/s41...

#SMIMemberPaper

Six degrees of TGFβ - Nature Immunology

TGFβ-mediated signals enable CD8+ T cells to establish tissue-residence. IL-4 and PD-1 are each connected to TGFβ signaling to regulate the formation of CD8+ T cell tissue residence in skin.

www.nature.com

3

Reposted by Society for Mucosal Immunology

Mucosal Immunology @mucosalimmunol.bsky.social · 15d

It’s #MucosalMonday and time for a new podcast episode! This month, @lakmalisilva.bsky.social discusses the oral mucosa with @marionbrunck.bsky.social. Plus medical mysteries with @ashu-mangalam.bsky.social and how RSV can impact the microbiota with @kknoop.bsky.social www.iheart.com/podcast/269-...

4 6

Reposted by Society for Mucosal Immunology

Mucosal Immunology @mucosalimmunol.bsky.social · 20d

Neutrophil ADAM10 promotes migration and inflammation in ARDS by modulating adhesion and chemokine signaling 🧪 www.mucosalimmunology.org/article/S193...

2 3

Society for Mucosal Immunology @societymucosalimm.bsky.social · 19d

SMI member Megan MacLeod and colleagues explore how influenza virus alters lung structural cells which can contribute to rapid immune protection following re-challenge in Nature Communications.

www.nature.com/articles/s41...

#SMIMemberPaper

Lung structural cells are altered by influenza virus leading to rapid immune protection following re-challenge - Nature Communications

Here the authors show that lung epithelial, fibroblast, and endothelial cells retain an imprint of influenza A infection, including increased MHCI/II expression and that re-infection is quickly controlled by a localized antiviral response acting before memory T cells are required.

www.nature.com

2

Society for Mucosal Immunology @societymucosalimm.bsky.social · 22d

It’s #MucosalMonday! 🎙️ A new episode of the Mucosal Immunology podcast drops next Monday, Sept 29. Until then, catch up with “Timing Exposure to Microbes” featuring Dr. Michael Silverman, brought to you by SMI and @mucosalimmunol.bsky.social

Listen here -> bit.ly/4lxNC7F

3 2

Society for Mucosal Immunology @societymucosalimm.bsky.social · 25d

In the latest SMI Oral History Project, Dr. Mathias Hornef sits down with Dr. Natalia Torow to share their remarkable career in mucosal immunology.

Watch here -> socmucimm.org/about/smi-or...

#MucosalImmunology

1

Society for Mucosal Immunology @societymucosalimm.bsky.social · 26d

SMI Member R Lee Reinhardt reviews type-2 respiratory responses in "An Outside-In View of the Beneficial and Detrimental Impact of Type-2 Inflammation in the Lung" ->

onlinelibrary.wiley.com/doi/10.1111/...

#SMIMemberPaper #MucosalImmunology

onlinelibrary.wiley.com

Reposted by Society for Mucosal Immunology

IMPACTT Microbiome @impactt-microbiome.bsky.social · 26d

Mucosal Immunology (@societymucosalimm.bsky.social), the official publication of the Society of Mucosal Immunology (SMI), is proud to sponsor #HavingIMPACTT2025 and foster discussion of immunity at mucosal surfaces. Learn more at mucosalimmunology.org

Mucosal Immunology: THE SMI JOURNAL. Dedicated to Mucosal Immunology. 2-year impact factor (2024): 7.6. www.mucosalimmunology.org

2 4

Society for Mucosal Immunology @societymucosalimm.bsky.social · Sep 11

Gut-lung crosstalk: Rapid group-2 innate lymphoid cell mobilization from the intestine aids in early lung defense and repair from SMI member Lee Reinhardt
@cp-cellreports.bsky.social

cell.com/cell-reports...

#SMIMemberPaper #MucosalImmunology #Immunology

Rapid group-2 innate lymphoid cell mobilization from the intestine aids in early lung defense and repair

Can et al. show that circulating group 2 innate lymphoid cells (ILC2s) rapidly migrate from the intestine to the lung after helminth infection. These early responders bolster type-2 immunity and barri...

cell.com

1

Reposted by Society for Mucosal Immunology

Mucosal Immunology @mucosalimmunol.bsky.social · Sep 10

T-cell immunity against influenza virus does not require Th1 or Th17 master regulator transcription factors www.mucosalimmunology.org/article/S193...

2 2

Society for Mucosal Immunology @societymucosalimm.bsky.social · Sep 9

Placental inflammation-driven T cell memory formation promotes allergic responses in offspring via endogenous glucocorticoids in this work from SMI member Heung Kyu Lee: www.sciencedirect.com/science/arti...

#SMIMemberPaper #MucosalImmunology #Immunology

Placental inflammation-driven T cell memory formation promotes allergic responses in offspring via endogenous glucocorticoids

Maternal exposure to environmental change during pregnancy is a critical determinant of offspring health and disease. Previous epidemiological studies…

www.sciencedirect.com

Reposted by Society for Mucosal Immunology

Mucosal Immunology @mucosalimmunol.bsky.social · Sep 1

#Leukotriene 4 regulates T cell responses during #CMV infections: www.mucosalimmunology.org/article/S193...

1 2 4

Reposted by Society for Mucosal Immunology

Mucosal Immunology @mucosalimmunol.bsky.social · Sep 4

Expansion of genital Tregs reduces neutrophil influx and maintains mucosal barrier integrity during inflammatory bacteria challenge in this work from Lyle McKinnon @sijuiwhatwhat.bsky.social and colleagues
www.mucosalimmunology.org/article/S193...

1 3 6