Lightnews — Scholar-powered news

Reposted by Rong Fan

Cancer Research UK Scotland Institute @cruk-si.bsky.social · May 29

And now for our final speaker of #BICC2025: Rong Fan (@rongfan8.bsky.social) from @yale.edu who will be telling us about his spatial multi-omics work in lymphoma

3 10

Reposted by Rong Fan

Gonçalo Castelo-Branco @gocastelobranco.bsky.social · Jul 10

Great to catch up with @rongfan8.bsky.social in Marseille, where we both end up for two completely unrelated conferences!

1 12

Reposted by Rong Fan

Gonçalo Castelo-Branco @gocastelobranco.bsky.social · Aug 12

Join us at the FENS Single-Cell & Spatial Omics Winter School with:

@sarabiz86.bsky.social
@rongfan8.bsky.social
@gokcegroup.bsky.social
@gioelelamanno.bsky.social
@sj-marzi.bsky.social
@jplopez-atalaya.bsky.social
Ana Falcão
Florian Rosenberger
Gabriel Baró
Bosiljka Tasic
Barbara Treutlein

Federation of European Neuroscience Societies - FENS @fens.org · Aug 5

🌟 Registration is now OPEN! 🌟

Join the 2025-2026 #FENS-Hertie #WinterSchool and explore this year's topic – Single-cell and Spatial Omics to Understand Brain Heterogeneity! 🔬

📍 Alicante, Spain
🗓️ 11-17 Jan 2026

🔗 https://loom.ly/RM55lFQ

10 16

Rong Fan @rongfan8.bsky.social · Aug 16

Looking forward to the FENS neuroscience winter school in Jan 2026! 🤩🥳🤩

Federation of European Neuroscience Societies - FENS @fens.org · Aug 5

🌟 Registration is now OPEN! 🌟

Join the 2025-2026 #FENS-Hertie #WinterSchool and explore this year's topic – Single-cell and Spatial Omics to Understand Brain Heterogeneity! 🔬

📍 Alicante, Spain
🗓️ 11-17 Jan 2026

🔗 https://loom.ly/RM55lFQ

4

Rong Fan @rongfan8.bsky.social · Apr 23

This stunning science art comes from a lymphoma case diagnosed by my incredible friend, hematopathology director Mina Xu. Art inspired by science brings awareness and hope, and helps patients.

Yale Pathology @yalepathology.bsky.social · Apr 23

Congratulations to Zhiliang Bai, PhD, a Postdoctoral Associate in the Lab of @rongfan8.bsky.social at @yaleschoolofmed.bsky.social, for having an image he created chosen for the “The Beauty of Science,” art display outside the Cushing/Whitney Medical Library at YSM.

2 7

Rong Fan @rongfan8.bsky.social · Apr 16

💕💕💕

1

Rong Fan @rongfan8.bsky.social · Apr 13

Feeling truly privileged to work with my amazing colleagues Mina Xu and Coraline Mlynarczyk in this project. Thank you!

2

Rong Fan @rongfan8.bsky.social · Apr 13

We are incredibly grateful to Mark Foundation and Follicular Lymphoma Foundation for the ASPIRE award, supporting our research on decoding human follicular lymphoma progression and transformation.

The Mark Foundation for Cancer Research @themarkfdn.bsky.social · Mar 27

Another ASPIRE Award supports Rong Fan, Mina Xu, & Coraline Mlynarczyk at @yaleschoolofmed.bsky.social. Their research will use advanced spatial omics to map genetic changes & the microenvironment of FL tumors, predicting progression & treatment responses.
themarkfoundation.org/portfolio/en...

2 13

Rong Fan @rongfan8.bsky.social · Apr 13

I was unable to attend the YCC Annual Awards Ceremony this year due to urgent personal matters. When I heard the news, I was completely surprised and genuinely moved! Truly thankful to Yale Cancer Center for this recognition and the entire lab for their devotion to science! 🥰

1

Rong Fan @rongfan8.bsky.social · Apr 13

I am incredibly honored and deeply grateful for receiving the 2024 YCC Translational Cancer Research Award! Thank you Yale Cancer Center from the bottom of my heart for this recognition and for your continued support! 💕

medicine.yale.edu/news-article...

Yale Cancer Center Annual Awards

Formerly called the Conclave Awards, the 2025 Spring Yale Cancer Center awards honored research, clinical expertise, and support staff at the Hotel Marcel, New

medicine.yale.edu

1 1 13

Reposted by Rong Fan

The Moross Integrated Cancer Center (MICC) @miccresearch.bsky.social · Mar 23

@juliandownward.bsky.social @yuvalshaked.bsky.social @netaerez.bsky.social @idoamitlab.bsky.social @tcell.bsky.social @landau.bsky.social @zronai.bsky.social

1 6

Reposted by Rong Fan

The Moross Integrated Cancer Center (MICC) @miccresearch.bsky.social · Mar 23

Fabulous group photos from our recent conference in Athens !🎉 #MICC2025 Please feel free to share and tag :)
@peeperlab.bsky.social @yardenasamuels.bsky.social @leeat-keren.bsky.social @rongfan8.bsky.social @shouval.bsky.social @yogogurt.bsky.social @eriksahailab.bsky.social

1 3 9

Reposted by Rong Fan

Hao Yin @haoyin.bsky.social · Feb 24

ASTRO
Automated Spatial Whole-Transcriptome RNA-Expression wOrkflow
for Patho-DBiT
#SpatialRNAEncyclopedia
coding + noncoding RNAs

github.com/gersteinlab/...

vs ST-pipeline

Establishment of a non-coding RNA reference😎

@rongfan8.bsky.social bioRxiv 2025
www.biorxiv.org/content/10.1...

2 9

Reposted by Rong Fan

Hao Yin @haoyin.bsky.social · Feb 24

#SpatialRNAEncyclopedia
Patho-DBiT
#SpatialTranscriptomics FFPE

Spatial Co-mapping of RNA Expression Splicing Editing SNV AND ncRNAs (miRNA lncRNA rRNA snRNA)👹

in situ polyA tailing

10 μm/px➡️ >2000 genes Lymphoma

@rongfan8.bsky.social @cellcellpress.bsky.social 2025
www.cell.com/cell/fulltex...

2 20

Reposted by Rong Fan

Biomedical Picture of the Day BPoD @bpodaily.bsky.social · Feb 3

Connecting gene activity & precise location of protein function by Deterministic Barcoding in Tissue sequencing (DBiTplus)

📷: Archibald Enninful, Zhaojun Zhang et al
Mina Xu, Zongming Ma @rongfan8.bsky.social
@yale.edu in @biorxivpreprint.bsky.social

➡️: bpod.org.uk/archive/2025... &
AntDLewis

3 6

Rong Fan @rongfan8.bsky.social · Jan 28

Just picked up the beautiful offprint of our Patho-DBiT paper that was on the cover of Cell, highlighting its power to spatially explore molecular biology in human FFPE tissues 🤩🤩 . Congratulations to my phenomenal postdoc Zhiliang Bai and all amazing collaborators!!

6 48

Reposted by Rong Fan

bmes-cmbe.bsky.social @bmes-cmbe.bsky.social · Jan 4

Congrats Dr.Zhang for your postdoctoral travel award! Way to go with spatial transcriptomics! #cmbe2025 @rongfan8.bsky.social @yalebooks.bsky.social @yaleengineering.bsky.social

3 5

Rong Fan @rongfan8.bsky.social · Dec 7

truly honored to write a commentary piece to discuss spatial protein profiling in the context of multi-omics !

www.nature.com/articles/s41...

Integrative spatial protein profiling with multi-omics - Nature Methods

Spatial proteomics holds the potential to transform the study of proteins in situ in complex tissues, but it needs to be integrated with other layers of omics data to gain a holistic view of cellular ...

www.nature.com

2 9

Rong Fan @rongfan8.bsky.social · Dec 7

SPATIAL PROTEOMICS is the Method of the Year 2024!!! 🤩🤩🤩

www.nature.com/articles/s41...

Method of the Year 2024: spatial proteomics - Nature Methods

Approaches for profiling the spatial proteome in tissues are the basis of atlas-scale projects that are delivering on their promise for understanding biological complexity in health and disease.

www.nature.com

1 27 85

Rong Fan @rongfan8.bsky.social · Dec 7

Incredible #epigenetics conference organized by @mpi-ie.bsky.social and a wonderful community!!!

Max Planck Institute of Immunobiology and Epigenetics @mpi-ie.bsky.social · Dec 5

We ended day one on a high note with fantastic talks from @rongfan8.bsky.social and @mariekeoudelaar.bsky.social covering topics ranging from 3D genome folding to spatial multi-omics. It has been fantastic first day. 🤗

Marieke Oudelaar: »The interplay between nucleosome positioning and higher-order
3D genome folding«

Rong Fan: »Spatial Multi-Omics Mapping of Tissue Development, Aging and Disease«

10

Rong Fan @rongfan8.bsky.social · Nov 12

The second preprint presents an experiment workflow and a broadly applicable computional framework to integrate sequencing-based and imaging-based spatial omics data for the SAME tissue slide to construct a single cell spatial omics atlas.

www.biorxiv.org/content/10.1...

Integration of Imaging-based and Sequencing-based Spatial Omics Mapping on the Same Tissue Section via DBiTplus

Spatially mapping the transcriptome and proteome in the same tissue section can significantly advance our understanding of heterogeneous cellular processes and connect cell type to function. Here, we ...

www.biorxiv.org

5 14

Rong Fan @rongfan8.bsky.social · Nov 12

The first preprint reports on an all optical approach to map metabolic activities and high-plex immunofluorescence cell typing in the SAME tissue section to link single cell omics to metabolic function cell-by-cell directly in complex tissues 🤩🤩

www.biorxiv.org/content/10.1...

All-Optical Multimodal Mapping of Single Cell Type-Specific Metabolic Activities via REDCAT

Metabolism dictates a range of physiological functions in human health and disease. Metabolic activities vary substantially in different cell types and are influenced by local tissue environments. Des...

www.biorxiv.org

1 1 6

Rong Fan @rongfan8.bsky.social · Nov 12

My first post here on our research 🥳. Two preprints from my lab at Yale and Dr. Lingyan Shi’s lab at UCSD report same tissue section multi-modal spatial omics mapping! Please check them out. 🤩

1 16 63

Rong Fan @rongfan8.bsky.social · Jan 11

Spatial Multi-Omics for Cancer Systems Biology Workshop! It is organized by our NCI-funded cancer systems biology center‬⁩. We will highlight talks by the leaders in the field as well as some hands-on experiences in computational analysis of spatial multi omics data!
isbscience.org/spatial-mult...

isbscience.org

6