Rienk Eelkema

@rienkeelkema.bsky.social

470 followers 510 following 110 posts

I like making things. Like molecules, plants, photos, my kids happy. And food.
professor @ TU Delft, interested in complex systems, organic chemistry, soft materials, healthcare&biology

Videos

Materials science 30%

Chemistry 26%

Posts Replies Media Videos

Rienk Eelkema @rienkeelkema.bsky.social · 6h

Published a paper warning that something doesn't work as commonly accepted in SciRep some years ago, that journal has done some dubious things in the mean time though. I generally like the approach and integrity of CellRepPhysSci, I could imagine they might be up for something like this

Rienk Eelkema @rienkeelkema.bsky.social · 1d

Want to come to Maine? I wanted to contact your journal but GRC doesn't allow me to. Would be great to have you there

Rienk Eelkema @rienkeelkema.bsky.social · 1d

🔬 Registration Now Open!
GRC Systems Chemistry 2026
“Bridging Molecular Complexity and Multiscale Systems Integration”
📅 June 21 – 26, 2026
📍 Portland, Maine (USA)
www.grc.org/systems-chem...
Feel free to share this announcement with anyone who may be interested.
#GRC @systemschem-grc.bsky.social

Rienk Eelkema @rienkeelkema.bsky.social · 1d

The project was led by Dr. Benjamin Klemm, in close collaboration with Dr. Margherita Tavasso and Prof. Pouyan Boukany @pboukany.bsky.social. Funding from the @erc.europa.eu , Open Access publication.

Rienk Eelkema @rienkeelkema.bsky.social · 1d

The kinetics of drug release depend heavily on the type of nucleophilic trigger: thiols are fast, amines are much slower (minutes to days). Application of a gefinitib construct to a lung cancer cell model (A549) showed ~100% wound-closure inhibition upon signal activation.

Rienk Eelkema @rienkeelkema.bsky.social · 1d

These prodrugs can be activated by biologically relevant nucleophiles enabling precisely controlled drug release.
We went on to embed anti-cancer and antibiotic prodrugs into hydrogel scaffolds, testing them in aqueous and cellular environments.

Rienk Eelkema @rienkeelkema.bsky.social · 1d

Using a versatile azido-phenyl allyl bromide scaffold, we generated prodrugs from a range of amine-containing drug candidates. It’s quite straightforward to make these things, basically just mix the allylbromide and the drug, wait, and isolate by filtration.

Rienk Eelkema @rienkeelkema.bsky.social · 1d

🚀 Publication Alert!

In this work, we introduce a new strategy for developing tertiary amine–based prodrugs with dual functionality:
1️⃣ Signal-triggered drug activation
2️⃣ Covalent incorporation into polymer materials via a built-in clickable azido group

🔗 pubs.rsc.org/en/content/a...

Nucleophile-triggered prodrug release from polymer hydrogels

We present a new method to obtain tertiary amine-based prodrugs with dual functionality, enabling (i) signal-triggered drug activation and (ii) covalent incorporation in polymer materials through a cl...

pubs.rsc.org

Rienk Eelkema @rienkeelkema.bsky.social · 6d

ja daar was ik al bang voor. Kreeg ook een vrij nikserig antwoord van Nexus toen ik hiernaar vroeg, gaf weinig vertrouwen dat ze hem kritisch zouden bevragen. Gemiste kans, zwakke journalistiek.

Rienk Eelkema @rienkeelkema.bsky.social · 23d

Congratulations Job, very much deserved!

Reposted by Rienk Eelkema

Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 23d

If said women work for your competitors, I guess maybe

Reposted by Rienk Eelkema

Esther Ouwehand @estherouwehand.bsky.social · 23d

In tijden van radicaal-rechtse stormen, moet je niet meewaaien.

Onze rechtsstaat zal voluit moeten worden verdedigd en versterkt, in belang van mens en dier.

Onze brief aan verkenner Wouter Koolmees 👇

Reposted by Rienk Eelkema

Thomas M. Hermans @hermanslab.bsky.social · Oct 23

Want to learn chemical kinetics? Watch my online course (master level): youtube.com/playlist?list=PLMOBJket5g1zsNs-a8hlJ7ImVcWE180KR&si=FhqmABYzb2MDS-p3

Chemical kinetics course - YouTube

Chemical kinetics course Class 1: Historical introduction Class 2: 0-2nd order, equilibrium (analytical) Class 3: Reactions in series/parallel, Michaelis-Men...

youtube.com

Reposted by Margreet Zwarteveen, Rienk Eelkema

Lisa Westerveld 🌱 @lisawesterveld.bsky.social · Oct 20

Nou nee, dat mag niet.

Een school moet een veilige plek zijn voor álle leerlingen. Dat staat ook in de wet. Het afwijzen van homoseksuele relaties geeft de boodschap dat iemand niet zichzelf mag zijn.

Dat mag niet én is ronduit schadelijk.

nos.nl/nieuwsuur/co...

CDA-leider Bontenbal: religieus onderwijs mag botsen met grondrecht van gelijkheid

Dat religieuze scholen homoseksuele relaties afwijzen, is volgens CDA-leider Henri Bontenbal nu eenmaal een gevolg van de vrijheid van onderwijs. Daar wil hij niet aan tornen. "Een andere mening doet ...

nos.nl

Rienk Eelkema @rienkeelkema.bsky.social · Oct 1

Using a forged entry ticket should be encouraged in this particular case

Rienk Eelkema @rienkeelkema.bsky.social · Sep 22

Not entirely sure what it is we'll be consuming at my department's coffee break, but I'm all in.
#AIforthewin

Rienk Eelkema @rienkeelkema.bsky.social · Sep 20

Spreek je moerstaal! 🫠

Reposted by Robbert Sanderman, Martin Drenthen, Rienk Eelkema

Frans Timmermans @franstimmermans.groenlinkspvda.nl · Sep 20

NSB-vlaggen op het Malieveld. Geweld tegen de politie door extreemrechts. Onacceptabel. Dit zijn Trumpiaanse toestanden, gevoed door politici die angst en verdeeldheid zaaien.

Stil blijven is geen optie. Je moet je laten horen. Samen staan we sterker.

Reposted by Robbert Sanderman, Leo Lucassen, Rienk Eelkema

Voetnoot -Mark Ponte @voetnoot.bsky.social · Sep 19

“Het antifascisme of antifa is een veelvormige beweging die ageert tegen alle vormen van uiterst rechts, met name tegen nazisme, fascisme en neofascisme.”

Ondertussen ‘uiterst rechts’ gesteund door ‘liberalen’ in Nederland (in navolging van Trump):

Reposted by Rienk Eelkema

Rienk Eelkema @rienkeelkema.bsky.social · Aug 26

@nexusinstituut.bsky.social I understand that these douchebags like to write their own bios, but I do think you have the responsibility to address these issues at the conference. Will you?

Rienk Eelkema @rienkeelkema.bsky.social · Aug 26

Advancing American Freedom, which champions faith, family, and liberty as fundamental American values. In 2025, Pence received the John F. Kennedy Profile in Courage Award for his actions on January 6, 2021, when he risked his life and career to ensure the lawful transfer of presidential power.

Rienk Eelkema @rienkeelkema.bsky.social · Aug 26

education reform, and infrastructure investment while maintaining fiscal responsibility. His accomplishments in Indiana led to his election as the 48th Vice President of the United States. Pence’s conservative philosophy, inspired by Ronald Reagan, led him to found the organization

Rienk Eelkema @rienkeelkema.bsky.social · Aug 26

He worked as an attorney, hosted a talk show, served six terms in Congress—where he advocated for limited government and fiscal responsibility—and was later elected the 50th Governor of Indiana. In that role, he focused particularly on tax cuts, job creation,

Rienk Eelkema @rienkeelkema.bsky.social · Aug 26

Translation: Mike Pence was born on June 7, 1959, in Columbus, Indiana, into a family that embodied the American Dream and instilled in him the values of hard work, faith, and family. After graduating from Hanover College and the Indiana University School of Law, he began his multifaceted career.

Rienk Eelkema @rienkeelkema.bsky.social · Aug 26

Nexus Conference 2025: Mike Pence attending. Interesting to see how his bio seems to gloss over that a major highlight of his life was being a christian fascist who enabled Trump and the misery and suffering that came out of that.
@nexusinstituut.bsky.social