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PreOperative Performance @preoperative.bsky.social · 9d

Sharing work presented at the @esmrmb.bsky.social meeting in Marseille earlier this month, demonstrating our anisotropic diffusion phantom’s utility with higher-order tensor diffusion data models.

#Neuroscience #neuro #diffusionMRI #mri #dki #ESMRMB2025

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PreOperative Performance @preoperative.bsky.social · 16d

PreOperative Performance is delighted to attend the International Society of Tractography meeting in Bordeaux this week!

Say hello, DM or email

✉️: [email protected]

@tractography.bsky.social

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PreOperative Performance @preoperative.bsky.social · 18d

Some last scenes from near Marseille’s Vieux Port. Marseille was founded ~ 600BCE by Phoenician sailors and despite modern infrastructure requirements has wonderfully preserved layers of history.

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PreOperative Performance @preoperative.bsky.social · 18d

Thank you @esmrmb.bsky.social and thank you Marseille!

This was a greatly enjoyable meeting and I was delighted to see sessions dedicated to the importance of medical imaging quality (control & assurance) and reference standards.

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PreOperative Performance @preoperative.bsky.social · 20d

Poster day! @esmrmb.bsky.social

PreOperative Performance @preoperative.bsky.social · 20d

#MRI #diffusionMRI #DKI #HARDI #neuroscience #neurorad #neurosky

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PreOperative Performance @preoperative.bsky.social · 20d

As these imaging modalities are sensitive to noise and inter system variability, reference standards such as our anisotropic diffusion phantom can verify repeatability and consistency of measurements, with applications in #biomarker characterisation, and multi-system and longitudinal studies.

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PreOperative Performance @preoperative.bsky.social · 20d

Day 3 of #ESMRMB2025 begins shortly. It’s poster day!

In poster PG353 PreOperative Performance’s technology is applied to higher order tensor models of diffusion MRI data which can resolve complex neural architecture such as areas with crossing fibers.

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PreOperative Performance @preoperative.bsky.social · 23d

#ESMRMB2025 #microstructuralimaging #UHF #MRI #radsky #diffusionMRI

PreOperative Performance @preoperative.bsky.social · 23d

Join us at the preclinical imaging workshop session on Wednesday 8th at #ESMRMB meeting in Marseille.

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PreOperative Performance @preoperative.bsky.social · 23d

PreOperative Performance has metrology phantoms, compatible with NMR and ultra-high field (UHF) imaging workflows, that can support this validation, provide quality controls that inform human-studies, and strengthen interpretability and impact.

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PreOperative Performance @preoperative.bsky.social · 23d

…that can be incorporated into human-centered investigations.

The characterisation of imaging features, structures and biomarkers, relevant to understanding disease pathways and progression, require validation solutions.

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PreOperative Performance @preoperative.bsky.social · 23d

Preclinical imaging, including studies of ex-vivo tissue and organoid models, play a critical role in advancing MR imaging research by providing the means to explore the biological underpinnings of disease, refine imaging techniques and uncover insights…

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PreOperative Performance @preoperative.bsky.social · Sep 29

Ensure you take some time to check out abstract "Assessing measurement consistency of a novel anisotropic phantom for higher order diffusion tensor MRI sequences' (PG353).

If you’re attending, we’d love to meet in Marseille!

Follow us & DM to connect!

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PreOperative Performance @preoperative.bsky.social · Sep 29

We’re looking forward to attending #ESMRMB 2025 from October 8-11th
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We look forward to meeting old friends and new and engaging in discussions about our anisotropic diffusion phantom technology. We are delighted to share that our technology will feature in the scientific program.

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Reposted by PreOperative Performance

PreOperative Performance @preoperative.bsky.social · Jul 29

This image shows 3 pairs of crossing white matter simulating modules with 3 different bundle diameters from our phantom POP-0005. Note that the bundles with smallest diameter are sub-voxel dimensions.

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Reposted by PreOperative Performance

PreOperative Performance @preoperative.bsky.social · Aug 25

MR imaging at 1.5T vs 3T have different advantages. 🧠

Aside from cost considerations, imaging at 3T delivers higher signal to noise (SNR) enabling increased spatial resolution, critical for identification of smaller white matter tracts and changes that may result from injury or disease.

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PreOperative Performance @preoperative.bsky.social · Aug 25

Through use of PreOperative Performance’s phantom technology, we can explain tractography performance and determine the resolvability of tracts that can be achieved given their sizes, specific to the MR system and protocol used.

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PreOperative Performance @preoperative.bsky.social · Aug 25

In contrast, at 1.5T, several seeds were required on most bundles and the thinnest bundles were not trackable.

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PreOperative Performance @preoperative.bsky.social · Aug 25

The 3T data quality and protocol resulted in well-defined tracts (all 6 with 3 varying diameters ) when seed-based probabilistic tractography was performed. Multiple seeds were only required for the thinner bundles.

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PreOperative Performance @preoperative.bsky.social · Aug 25

In particular, for 1.5T data, there is a lot of green in the horizontal bundles on slice #52 which is why it was hard to obtain tracking for those as shown in B (3 seeds needed: left, middle and right) to get to termination points (yellow spheres).

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PreOperative Performance @preoperative.bsky.social · Aug 25

Data were collected with same resolution and b-value (b=1000 s/mm^2) but different number of gradient directions. We can see that the 3T V1 results are much less noisy (all 3 slices show exclusively green and red in the vertical and horizontal bundles, respectively).

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PreOperative Performance @preoperative.bsky.social · Aug 25

In this diagram we show a comparison of results for fitting the tensor model to data collected at 2 field strengths and the resulting tractography.

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PreOperative Performance @preoperative.bsky.social · Aug 25

Imaging at 1.5T is not without its advantages, there are less distortions at lower field and some patients with implanted medical devices (such as cochlear implants) may be conditionally scanned at 1.5T and not at higher field strengths.

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PreOperative Performance @preoperative.bsky.social · Aug 25

MR imaging at 1.5T vs 3T have different advantages. 🧠

Aside from cost considerations, imaging at 3T delivers higher signal to noise (SNR) enabling increased spatial resolution, critical for identification of smaller white matter tracts and changes that may result from injury or disease.

1/8

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