We built in the US the best scientific industry in world history and it is dying.

Fixing just the damage done since Jan 20 would take years. Maybe a decade. The program staff, SROs, and brilliant talent is not coming back.

Thanks! Complimentary results to what you found in EAE

Thanks! So far I think information is limited on D/Q ability to cross the BBB, but this study here (doi.org/10.1038/s415...) shows elevated levels in csf of D but not Q. Newer next generation senolytics that target apoptosis pathways better may cross better though.

‪Congratulations Phil @philgrossphd.bsky.social and a huge thank you to all the lab members and collaborators for their contributions to our project on the role of senescence in remyelination, which has now been published in @naturecomms.bsky.social! 😀 www.nature.com/articles/s41...

Check out this exciting work by @philgrossphd.bsky.social in the @jkhuang.bsky.social lab! Thanks for asking us to be a part of it

A big thank you to my mentor @jkhuang.bsky.social and members of the lab @zeebamehrin.bsky.social and all of our collaborators who were amazing to work with @mengmengfu.bsky.social @jrplemel.bsky.social

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We find this is (partially) mediated by CCL11, which we find is sufficient to limit oligodendrocyte maturation, and has been shown to impair neuro-regeneration w/ age and is involved in long covid neurological deficits (as shown by @michellemonje.bsky.social, among others)

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Excited to finally have this published! Out today in @naturecomms.bsky.social, we show that following demyelination in a mouse model of Multiple Sclerosis, treatment of senescent microglia with senolytics leads to improved remyelination. www.nature.com/articles/s41...

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Very excited that Phil Gross @PSGrossScience @georgetown #IPN #GUBiology has successfully defended his PhD thesis on the role of cellular senescence in CNS remyelination. Next stop a postdoc at the NIH. Congratulations Dr. Gross! 🎉🎉🎉🍾🍾🍾