Lightnews — Scholar-powered news

Reposted by Nicolas Robine

Dan Landau @landau.bsky.social · 1d

Big, beautiful trees!!

SMART-PTA for whole-genome+transcriptome on thousand of single cells from the normal human esophagus 🤯 Massively scaling up the power of scWGS to build deep phylogenies and chart somatic evolution from birth throughout life.

www.biorxiv.org/content/10.1...

1 12 40

Nicolas Robine @nicorobine.bsky.social · 2d

Fire on board is scary! My Saturday afternoon sailing was more relaxed

1 2

Nicolas Robine @nicorobine.bsky.social · 3d

Je viens d’essayer et il y arrive à peu près, mais ensuite il me propose de me montrer ce que les autres pensent de moi 😱😱😱

1

Nicolas Robine @nicorobine.bsky.social · 3d

What else? Canelés! 🤣

1

Reposted by Nicolas Robine

Daniel Durocher @durocher1.bsky.social · 4d

9 days to go:
* 2 x open positions!
* Exceptional environment, competitive start-up package
* University of Toronto appointments
* Toronto has great (and peaceful) quality of life!

Daniel Durocher @durocher1.bsky.social · Aug 28

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.

www.nature.com/naturecareer...

Please repost!

32 13

Nicolas Robine @nicorobine.bsky.social · 4d

Still awesome. And here is my new favorite sequencing machine:

Scene of sequencing samples in One Battle After Another

1

Nicolas Robine @nicorobine.bsky.social · 6d

i am pretty sure he ate some (and how he found it on the side of the road is whole other story)

22

Nicolas Robine @nicorobine.bsky.social · 6d

Ouch. I’ve heard the worse with broken ribs is that you can’t laugh anymore without lots of pain. Adjust your online diet accordingly (by that I’m not sure if I mean turn off French or US political news!)

1

Nicolas Robine @nicorobine.bsky.social · 6d

isn't that the entire "raison d'etre" of synthetic biology?

4

Nicolas Robine @nicorobine.bsky.social · 7d

I found a doctor to get a second opinion for my dad 6000km away and it let to a dramatic improvement in the health condition that was plaguing his (and my mother's) life.
Hard to tell if it would have happened without Twitter.

Conrad Hackett @conradhackett.bsky.social · 7d

Has anything great happened in your life because of social media?

5

Reposted by Nicolas Robine

Nuria Lopez-Bigas @nlbigas.bsky.social · 7d

🚨 New paper alert!

Sex and smoking bias in the selection of somatic mutations in human bladder

www.nature.com/articles/s41...

by @raquelbmi.bsky.social, @ferriol.bsky.social et al (in collaboration with Rosana Risques lab in @uwmedicine.bsky.social)

Sex and smoking bias in the selection of somatic mutations in human bladder - Nature

Sex bias and association with smoking history identified in the landscape of driver mutations and clonal expansions in normal human bladder tissue may explain the higher bladder cancer risk in men and smokers.

www.nature.com

2 29 67

Nicolas Robine @nicorobine.bsky.social · 7d

« I drive a Lambo and publish in Nature (Publishing Group) »

3

Reposted by Nicolas Robine

Matthew Neville @mattneville.bsky.social · 7d

Now published! Our paper on:
(1) Accurate sequencing of sperm at scale
(2) Positive selection of spermatogenesis driver mutations across the exome
(3) Offspring disease risks from male reproductive aging
[1/n]
www.nature.com/articles/s41...

Sperm sequencing reveals extensive positive selection in the male germline - Nature

A combination of whole-genome NanoSeq with deep whole-exome and targeted NanoSeq is used to accurately characterize mutation rates and genes under positive selection in sperm cells.

www.nature.com

3 49 82

Nicolas Robine @nicorobine.bsky.social · 7d

Meilleurs Ouvriers de France?
Non mais en vrai, l’innovation c’est que le prix aille à des chimistes et pas des biologistes déguisés!

1

Nicolas Robine @nicorobine.bsky.social · 8d

Pretty bold to call a startup "Soufflé Therapeutics". I am not saying we're in a bubble, but as we say in the French "c'est gonflé"
www.souffletx.com
endpoints.news/souffle-ther...

a pan of food is being baked at 200 degrees for 20 minutes

ALT: a pan of food is being baked at 200 degrees for 20 minutes

media.tenor.com

1 6

Nicolas Robine @nicorobine.bsky.social · 8d

One more Nobel for Google? Michel Devoret is « is the Chief Scientist at Google Quantum AI » (en.m.wikipedia.org/wiki/Michel_...)

2 1 4

Nicolas Robine @nicorobine.bsky.social · 9d

L'originalité de son parcours c'est quand meme qu'il habite au Canada depuis pres de 20 ans!

2

Nicolas Robine @nicorobine.bsky.social · 9d

Can’t wait to hear her story between the 2001 paper and now…

1 1

Nicolas Robine @nicorobine.bsky.social · 9d

Y a un New Berlin, NY aussi mais j’y suis allé et c’est tout petit. Leur bibliothèque doit tenir dans ma cuisine…

Nicolas Robine @nicorobine.bsky.social · 9d

Or would speak with such a Wisconsin accent

1 7

Nicolas Robine @nicorobine.bsky.social · 10d

And even the tomato on the side looks fresher! Amazing! 🤣

1

Nicolas Robine @nicorobine.bsky.social · 14d

Chaplin was spot on in 1940: youtu.be/isLNLpxpndA?...

2

Nicolas Robine @nicorobine.bsky.social · 16d

Am I right in thinking that the only way it would work is if tickets for non-US movies were double the price? Wouldn’t it be a perfect illustration of the fact that it’s US customers who ultimately pay for the tariffs?

2

Nicolas Robine @nicorobine.bsky.social · 17d

The film is glorious but aren’t the last 10 minutes superfluous (or did I miss something)?

Nicolas Robine @nicorobine.bsky.social · 18d

Friday night Tennis Grand Challenge with @andreaventura.bsky.social! @cancergrand.bsky.social Team SAMBAI vs Team eDyNAmiC! Lots of fun!

2 9