NanoImaging Services
@nanoimaging.bsky.social
180 followers 370 following 63 posts
We are a cryoEM-focused US-based CRO (we own 3 microscopes on the West Coast, and 3 microscopes on the East Coast), and we acquired Proteos in Kalamazoo, MI, in January of this year. Contact us for cryoEM, gene-to-structure, or protein production.
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nanoimaging.bsky.social
🧪 Conflicting results from DLS? #CryoTEM imaging can provide quantitative and qualitative data for smaller particles, like iron nanoparticle formulations, all in one study. Reach out to [email protected] to learn how cryo-TEM imaging can help you meet milestones faster.
nanoimaging.bsky.social
🚀 Fast track your #HPV therapeutics with #cryoTEM imaging. From initial characterization to 3D structures, we support you throughout the entire pipeline, including regulatory submissions.

🧪 Want the proof? See our published work on Gardasil®: www.nanoimagingservices.com/resources/ho...
nanoimaging.bsky.social
🧪 Are you using cryo-EM to look at small soluble proteins? Walk through each stage from protein production to structure determination, with practical insights and lessons from a recent case study on CYP3A4 with live Q&A.

Register: nimgs.zoom.us/webinar/regi...
nanoimaging.bsky.social
When it comes to #lentivirus characterization, seeing is believing. Traditional analytical methods tell you what's there, but #cryoTEM shows you exactly how it's organized.

Learn more: www.nanoimagingservices.com/nanoparticle...
nanoimaging.bsky.social
How do you choose a nanoparticle characterization method? While there are many techniques available, cryo-TEM stands out by revealing information other methods miss.

Dive into the comparison: www.nanoimagingservices.com/about/blog/v...
nanoimaging.bsky.social
Ever wondered how buffers impact #cryoEM structures?

🧪 DMSO and cryoprotectants can be tolerated at low concentrations. If you're curious if your buffer will be compatible, schedule a call with our experts: www.nanoimagingservices.com/contact
nanoimaging.bsky.social
Are you looking for comprehensive, reliable particle sizing analysis? From LNPs to iron nanoparticles, cryo-TEM semi-automated particle contouring and sizing provides precise particle size distribution measurement for a range of samples.

Learn more at www.nanoimagingservices.com/nanoparticle...
nanoimaging.bsky.social
🧪 Ever wondered what the difference is between #cryoEM and #negativestain #TEM is? Find out in today's FAQ Friday!
nanoimaging.bsky.social
Do you know how #LNPs show up in #cryoTEM versus negative stain TEM?

Want to learn more about the advantages of cryo-TEM for LNPs and other #liposomal samples? Tune in for the full webinar from Dr. Maria (Mandy) Janssen:
Enhance LNP Development: Cryo-TEM & Automated Image Analysis Tools
Join Dr. Mandy Janssen, Scientific Director of Characterization at NIS, to:- Discover how cryo-TEM enables high-resolution visualization of individual LNPs i...
youtu.be
nanoimaging.bsky.social
During a recent webinar, we were asked, “How does automated cryo-TEM particle picking for AAV full/empty capsids compare to other orthogonal methods?”

Watch the webinar in full for a great explanation of cryo-TEM imaging & analysis of AAV, and more of your great questions: youtu.be/w7kRfNZX_SI
nanoimaging.bsky.social
Poor contrast TEM images got you feeling grey? No problem!

Our latest tutorial will help you quickly & easily enhance the contrast and add scale bars to your #cryoTEM or negative stain TEM images so they’re ready for publication:
www.nanoimagingservices.com/about/blog/e...
nanoimaging.bsky.social
Did you miss our webinar last week? You can now catch this amazing talk from Dr. Mandy Janssen about #cryoTEM #LNP characterization, NIS’s proprietary AI tools for image analysis, and a case study showing unique insights only cryo-TEM can provide.

Catch it here:
Enhance LNP Development: Cryo-TEM & Automated Image Analysis Tools
youtu.be
nanoimaging.bsky.social
Are you struggling to solve the structure of your #RNA molecule? Cryo-EM study RNA in its native, unbound state, without the influence of associated proteins?

Learn more about the potential of #cryoEM single particle analysis for protein-free RNA: www.nanoimagingservices.com/about/blog/u...
Unlocking the Secrets of RNA: Protein-Free Structure Determination w/ Cryo-EM
Unlock the secrets of RNA molecules with cryo-EM. High resolution data collection & structure determination with cryo-EM for structure based drug discovery at NIS.
www.nanoimagingservices.com
nanoimaging.bsky.social
Unexpected results in your #LNP formulations? Join our webinar + Q&A to learn how #cryoTEM imaging can help provide answers.

We will reveal how cryo-TEM can provide reliable, reproducible data (size, morphology, lamellarity, blebs) in one dataset.

Sign up: nimgs.zoom.us/webinar/regi...
nanoimaging.bsky.social
Have you signed up yet? In just 1 week, Dr. Mandy Janssen will be giving a webinar + Q&A diving into the applications of #cryoTEM for #LNP development!

Don't miss out on this deep dive: nimgs.zoom.us/webinar/regi...

Can't make it live? Sign up to get a recording, or send in your questions!
nanoimaging.bsky.social
FAQ Friday! Dr. Sarah Strassler Sulley touches on the differences between cryo-EM and HDX for epitop emapping.

Want more? Check out our blog with an in-depth technique comparison: www.nanoimagingservices.com/about/blog/e...
nanoimaging.bsky.social
Looking for ways to enhance your #LNP analysis tools?

Dr. Mandy Janssen will present how #cryoTEM imaging & automated analysis can reveal multiple CQAs all in one dataset.

Questions? Stick around after the webinar for a Q&A with Mandy.

Sign up: nimgs.zoom.us/webinar/regi...
nanoimaging.bsky.social
How big are cryo-EM grids exactly? Find out!
nanoimaging.bsky.social
It's tomorrow! Join us to learn about automated cryo-TEM analysis of AAV full/empty capsid ratios.

Can't make it? Sign up anyway to receive a recording.

Don't miss this webinar + Q&A session: nimgs.zoom.us/webinar/regi...
nanoimaging.bsky.social
Webinar! Enhance LNP Development: Cryo-TEM & Automated Image Analysis Tools

Enable high-resolution visualization of LNPs in near-native state, analyze multiple CQAs in 1 dataset, & use automated image analysis tools for quantitative measurements.

Register: nimgs.zoom.us/webinar/regi...
nanoimaging.bsky.social
One week out! Join us for a webinar, "Automated Cryo-TEM Analysis of AAV Empty/Full Capsid Ratios".

Whether you're troubleshooting or aiming to streamline AAV manufacturing process, we'll demonstrate how cryo-TEM can drive faster informed decisions.

Sign up: nimgs.zoom.us/webinar/regi...