Mateusz Konczal
@mkonczal.bsky.social
140 followers 160 following 18 posts
Evolutionary and population genomics Assistant Professor in Poznan, Poland 🇵🇱
Posts Media Videos Starter Packs
Pinned
Our latest preprint shows that in translocated invasive guppy population, genetic load is reshaped by purging and admixture. A bottleneck purged strongly deleterious mutations, but admixture reversed this effect while reducing the load of weakly deleterious mutations. www.biorxiv.org/content/10.1...
Interplay between purging and admixture shapes genetic load in an invasive guppy population
Demographic history can shape the genetic load of populations by influencing the efficacy of selection, levels of heterozygosity, and by incorporation of new variants via gene flow. Understanding thes...
www.biorxiv.org
Reposted by Mateusz Konczal
Anthropocene Canceled? 🚯 @ecosocialism1.bsky.social
monthlyreview.org/articles/has...
>>> Of course NOT <<<
The evidence speaks for itself.
No geologists, epochs or hype required.
theconversation.com/the-anthropo... 🌍⚒️🌐🧪
Reposted by Mateusz Konczal
🚀 We’re hiring a Postdoc!

Join our group in Poznan, Poland to study meiotic crossover recombination in plants 🌱 Highly motivated & enthusiastic candidates are welcome!
📅 Deadline: Nov 1, 2025

🔗 ibmib.web.amu.edu.pl/wp-content/uploads/2025/09/Postdoc_position-2025-Ziolkowskis-Lab.pdf
One of my favourite examples for #conservation #genetics classes. It reminds me that with October #TeachingIsComming
Intense ivory poaching has led to the evolution of tusklessness in some African elephant populations, which might reduce poaching, but also happens to be an X-chromosome–linked dominant trait that is lethal to males #EleFunFactFriday #TheMoreYouKnow 💫 🧪 🐘

www.science.org/doi/10.1126/...
Ivory poaching and the rapid evolution of tusklessness in African elephants
Intensive ivory poaching during a period of civil conflict caused the rapid evolution of tusklessness in an African elephant population.
www.science.org
Reposted by Mateusz Konczal
Interplay between purging and admixture shapes genetic load in an invasive guppy population https://www.biorxiv.org/content/10.1101/2025.09.12.675788v1
Our latest preprint shows that in translocated invasive guppy population, genetic load is reshaped by purging and admixture. A bottleneck purged strongly deleterious mutations, but admixture reversed this effect while reducing the load of weakly deleterious mutations. www.biorxiv.org/content/10.1...
Interplay between purging and admixture shapes genetic load in an invasive guppy population
Demographic history can shape the genetic load of populations by influencing the efficacy of selection, levels of heterozygosity, and by incorporation of new variants via gene flow. Understanding thes...
www.biorxiv.org
Reposted by Mateusz Konczal
Reposted by Mateusz Konczal
Fighting to persist: Genetic rescue increases long-term fitness despite elevated genetic load https://www.biorxiv.org/content/10.1101/2025.09.06.673525v1
Check out our latest work! We experimentally showed that #genetic #rescue works: in the bulb mites, boosting genome-wide variation improved survival for 20 generations in high temp. Elevated genetic load or sexually selected traits? Barely mattered. #Conservation

www.biorxiv.org/content/10.1...
Reposted by Mateusz Konczal
@neelamporwal.bsky.social ‘s talk about estimating extinction risks under sexual selection using simulations, at PEC2025 won the first prize for the best student talk. So, should animals swipe right for survival?🐧
Reposted by Mateusz Konczal
🌎👩‍🔬 For 15+ years biology has accumulated petabytes (million gigabytes) of🧬DNA sequencing data🧬 from the far reaches of our planet.🦠🍄🌵

Logan now democratizes efficient access to the world’s most comprehensive genetics dataset. Free and open.

doi.org/10.1101/2024...
Reposted by Mateusz Konczal
Reposted by Mateusz Konczal
Fantastic dental calculus and where to find it

Johnny Richards and team (@markella-morait.bsky.social + curators from 5 museums) survey >140 mammalian species with >1,600 specimens to understand what factors determine dental calculus formation. #aDNA #museomics
www.biorxiv.org/content/10.1...
Examples of dental calculus in different mammalian species ranked by amount from 0 (no calculus) to 3 (full incrustation)
Reposted by Mateusz Konczal
With #eseb2025 coming to a close, it is time to start making plans for 2026. Interested in the interface of evolution 🧬 and ecology 🌳? Come to our #ExE conference hosted by @uniexecec.bsky.social in beautiful #Cornwall. Leave your email address at tinyurl.com/EvolxEcol to join our mailing list!
Small update:
Plenaries and Nosil talks: "Nature/Science" in the bottom right of a slide #eseb2025
#eseb2025 talks were great so far. Subjective ranking of the most common quotes:
- theory and modeling: "with this very simple approach"
- genomics: "using methodology you all know"
- plenaries: "Nature/Science" in the bottom right of a slide
- posters: "una cerveza por favor"
Reposted by Mateusz Konczal
We are having fantastic time presenting and discussing our work at #ESEB2025

- Neelam Porwal answered a question "How sexual selection shapes small populations demography under recurrent heatwaves"
#eseb2025 talks were great so far. Subjective ranking of the most common quotes:
- theory and modeling: "with this very simple approach"
- genomics: "using methodology you all know"
- plenaries: "Nature/Science" in the bottom right of a slide
- posters: "una cerveza por favor"
Reposted by Mateusz Konczal
Stuart et al. show footprints of selection after near-extinction: genetics of wild and captive Lord Howe stick insect show that after a severe bottleneck, inbreeding appears to remove harmful mutations via increased homozygosity.

🔗 doi.org/10.1093/molb...

#selection #evobio #molbio
Purging of Highly Deleterious Mutations Through an Extreme Bottleneck
Abstract. Transitions to captivity often produce population bottlenecks. On the one hand, bottlenecks increase inbreeding and decrease effective population
doi.org
"Dissertationibus conscriptis et publice defensis." What a day it was! Congratulations @k-burda.bsky.social So proud of you
Gratulacje!
@k-burda.bsky.social for defending her PhD titled “Determinants of genetic load in natural populations of guppies”
She estimated per-generation mutation rate in guppies and explored how demographic events affect the buildup or removal of harmful variation in their natural populations.