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Patients with limited metastatic/progressive cancers had good rates of local control and favorable survival with SBRT and no systemic therapy, according to a multicenter retrospective study from the Middle East.
https://www.medpagetoday.com/hematologyoncology/othercancers/117929
Good Cancer Control, Survival With SBRT for Limited Metastatic/Progressive Disease
Local control of 86%, 80% at 1 and 2 years without systemic therapy in limited-resource setting
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Three GLP-1 receptor agonists had generally comparable cardiorenal outcomes when used in type 2 diabetes, a retrospective comparative effectiveness study indicated.
https://www.medpagetoday.com/endocrinology/diabetes/117917
How Do GLP-1 Drugs Stack Up for Cardiorenal Benefits in Diabetes?
Study compares semaglutide, liraglutide, and dulaglutide
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medpagetoday.com
FDA cleared the Elecsys pTau181 test as the first blood-based biomarker to aid in the initial assessment of Alzheimer's disease and other causes of cognitive decline that can be used in the primary care setting.
https://www.medpagetoday.com/neurology/alzheimersdisease/117920
Alzheimer's Blood Test Cleared for Primary Care Use
Elecsys pTau181 test can help rule out Alzheimer's-related amyloid pathology
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medpagetoday.com
More than one in five young adults said they used cannabis or alcohol to help them sleep, with cannabis use being more common, according to data from the 2022-2023 Monitoring the Future Panel Study.

Read more at: https://www.medpagetoday.com/primarycare/sleepdisorders/117923?trw=no
Many Young Adults Use Cannabis or Booze as a Sleep Aid
While using these substances for sleep may work initially, it will backfire, researcher says
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Early heart rate changes after starting intermittent theta burst stimulation (iTBS) for major depressive disorder could help serve as a predictor of treatment response, a quadruple-blind crossover trial indicated.
https://www.medpagetoday.com/psychiatry/depression/117931
In Brain Stim for Depression, Early Heart Rate Changes May Signal Response
But personalization of stimulation sites didn't improve treatment response
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In a small phase II trial, radiation-free treatment with pembrolizumab (Keytruda) and platinum-based chemotherapy alone proved promising for patients with unresectable, locally advanced NSCLC and high PD-L1 expression.
https://www.medpagetoday.com/hematologyoncology/lungcancer/117925
Radiation-Free Approach Promising for Some Locally Advanced Lung Cancers
In PD-L1-high subset, 67% alive and free of progression at 2 years with pembrolizumab and chemo
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Starches may be safe after all for fluid resuscitation in perioperative medicine, based on the PHOENICS non-inferiority trial addressing longstanding concerns from regulators and the public.
@asahq.bsky.social #ANES2025
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HES Volume Expander Comes Back With Redeeming Safety Data
PHOENICS trial addressed early postoperative renal function, other outcomes
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Remimazolam (Byfavo) is poised to open a new frontier in anesthesiology, but caution is warranted to ensure off-label use does not devolve into the Wild West.
@asahq.bsky.social #anes25
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Remimazolam: Spur on the New Benzo for Sedation or Rein It In?
Newer sedative-hypnotic is promoted as an answer to staffing issues
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Reposted by MedPage Today
sundermannaj.bsky.social
My new piece in @medpagetoday.com

We Can Stop Deadly Hospital Outbreaks - So Why Aren't We?

Genomic surveillance can prevent outbreaks from spreading, save lives, and costs.

So what’s holding it back from being implemented in hospitals?

#IDSky

www.medpagetoday.com/opinion/seco...
Opinion | We Can Stop Deadly Hospital Outbreaks -- So Why Aren't We?
Genomic surveillance can help contain local and nationwide threats
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medpagetoday.com
Private insurers were more likely than Medicaid to deny claims for fluoride varnish and well-child visits, both preventive services mandated to be covered by the ACA without patient cost-sharing, according to a new study.

https://www.medpagetoday.com/pediatrics/preventivecare/117913?trw=no
Private Insurers More Likely to Deny Claims for These Preventive Services in Kids
Such services are mandated to be covered without patient cost-sharing
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Reposted by MedPage Today
chloenazra.bsky.social
We cannot expect women to welcome motherhood in a country that believes in their inferiority, refuses to support them meaningfully, and treats their bodies as expendable machines for production.

My latest for @medpagetoday.com #medsky #forcedbirth

www.medpagetoday.com/opinion/seco...
Opinion | Pronatalism and Public Health Are Incompatible
Women won't choose motherhood in a climate that undermines women's health
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Increases in social media use during early adolescence were significantly associated with lower performance in key areas of cognitive function, according to data from the Adolescent Brain Cognitive Development (ABCD) study.

https://www.medpagetoday.com/pediatrics/generalpediatrics/117911?trw=no
Increasing Social Media Use in Preteens May Be Hurting Cognition Too
'Differences were modest but consistent,' according to researcher
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Nearly half of patients prescribed a GLP-1 receptor agonist were not filling the order, with certain factors playing a role, according to a cohort study.

Read more at: https://www.medpagetoday.com/endocrinology/diabetes/117892?trw=no
Large Number of GLP-1 Prescriptions Go Unfilled
Out-of-pocket costs likely play a role
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medpagetoday.com
States with larger undocumented populations spent more on emergency Medicaid, accounting for a mean of 0.9% of state Medicaid expenditures among states with the highest undocumented population share, a study showed.

Read more:
https://www.medpagetoday.com/publichealthpolicy/medicaid/117899?trw=no
Here's How Much Medicaid Spends on Undocumented Immigrants
Despite claims of 'wasteful spending,' actual expenditures are less than 1% of total budget
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Reductions in force (RIFs) have begun at HHS in response to the government shutdown, although one labor union says the firings are illegal and about half of those initially laid off at CDC were quickly reinstated.

https://www.medpagetoday.com/publichealthpolicy/washington-watch/117900?trw=no
Trump Administration Begins Firing Federal Health Workers Amid Shutdown
At CDC, about half of those fired on Friday were reinstated Saturday
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Doctors performing certain medical scans on patients taking GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) may need to consider how the medications affect imaging.

Read more at: https://www.medpagetoday.com/popmedicine/cultureclinic/117880?trw=no
GLP-1s May Throw Off Some Medical Scans
The latest quirk linked to GLP-1 receptor agonists is of more concern to doctors than patients
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Diet should be considered an important part of a patient's treatment along with medication, surgery, and other options, several experts said Wednesday at a "Food Is Medicine" meeting sponsored by Tufts University.
https://www.medpagetoday.com/primarycare/dietnutrition/117859
Experts Push to Expand Role of Nutrition in Medicine
Doctors should prescribe food just like they prescribe medications, expert suggests
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Should federal courts be required to abide by state laws when they consider interstate malpractice cases?

The Supreme Court mulled that exact issue in a case it heard earlier this week.

Read more at: https://www.medpagetoday.com/practicemanagement/medicolegal/117877?trw=no
SCOTUS Hears Oral Arguments in Case Involving a Medical Malpractice Lawsuit
Issue revolves around whether state filing rules apply if a case is heard in federal court
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medpagetoday.com
Short-interval retesting for human papillomavirus (HPV) infection showed potential as a triage option to identify patients with high-risk cervical neoplasia, a large Latin American study showed.
https://www.medpagetoday.com/hematologyoncology/cervicalcancer/117882
Short-Interval HPV Retesting Shows Triage Promise for Cervical Cancer Screening
Good sensitivity for high-risk cervical neoplasia, but cost-effectiveness studies needed
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