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Karges Group @kargesgroup.bsky.social · 4h

Proud to share our new @ChemRxiv preprint. We report on a novel Metal-to-Metal Electron Transfer Mechanism enabling Hydroxyl Radical Photoredox Catalysis in Hypoxic and Drug-Resistant Cancer Cells, addressing bottlenecks in photodynamic therapy. Please RT! chemrxiv.org/engage/chemr...

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Karges Group @kargesgroup.bsky.social · 7d

Check out our paper in @chemcomm.rsc.org about the Red-Light Excitation of Ru(II)-Pt(II) Tetranuclear Complex for Combined Photoactivated Chemotherapy and Photodynamic Therapy. Congrats to Pia, Eleni, Julia, and @nmontesdeocas.bsky.social ! @ruhr-uni-bochum.de dx.doi.org/10.1039/D5CC...

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Karges Group @kargesgroup.bsky.social · 13d

🚨 PhD Opportunity! 🚨
Join our group in Bioinorganic Chemistry to work on the synthesis & biological evaluation of metal complexes for anticancer therapy.
jobs.ruhr-uni-bochum.de/jobposting/8...

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Karges Group @kargesgroup.bsky.social · Jul 29

Check out our paper in @inorgchemfront.rsc.org about the Induction of Oncosis by Light Activation with an Ir(III) complex conjugated to Albumin. Congrats to Antonio, Zisis, and Lisa. Fantastic collaboration with @joseruizlab.bsky.social ! @ruhr-uni-bochum.de @um.es dx.doi.org/10.1039/D5QI...

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Reposted by Karges Group

Healthcare in Europe (DE) @health-europe-de.bsky.social · Jul 29

👉 Ein von der @kargesgroup.bsky.social an der @ruhr-uni-bochum.de entwickelter neuer Wirkstoffkomplex tötet Krebszellen auf eine so geschickte Art, dass sie im Sterben dem #Immunsystem den Weg zu #Metastasen zeigt, die sich an entfernten Orten im Körper entwickeln.

Sterbende Tumorzellen machen Metastasen zur Zielscheibe

Ein neuer Wirkstoff kann Krebszellen beseitigen und gleichzeitig das Immunsystem trainieren, solche Zellen überall im Körper zu vernichten.

healthcare-in-europe.com

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Karges Group @kargesgroup.bsky.social · Jul 18

Thanks Maniklal!

Karges Group @kargesgroup.bsky.social · Jul 18

Check out our paper in J. Med. Chem. @acsbiol.bsky.social @acsmedi.bsky.social about the induction of immunogenic cell death by a gallium complex for chemoimmunotherapy. Congrats to Zisis and Yassin! @ruhr-uni-bochum.de
dx.doi.org/10.1021/acs....

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Karges Group @kargesgroup.bsky.social · Jun 11

Honored to be giving the plenary lecture for the Inorganic Devision at the Brazilian Chemistry Conference #48RASBQ

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Karges Group @kargesgroup.bsky.social · Jun 6

Wonderful presenting some of our research at Universidade Federal de Juiz de Fora @ufjfoficial.bsky.social Thanks to Luiz for the kind invitation! @ruhr-uni-bochum.de

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Karges Group @kargesgroup.bsky.social · Jun 4

Check out our study in @acsmedi.bsky.social about the "Induction of Cuproptosis with a Highly Cytotoxic Tripodal Cu(II) Complex". Congrats to Ricarda and @nmontesdeocas.bsky.social @ruhr-uni-bochum.de
pubs.acs.org/doi/abs/10.1...

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Karges Group @kargesgroup.bsky.social · May 17

Wonderful presenting some of our studies at the BioOpen Conference in beautiful Łódź as part of the UNIC network. @ruhr-uni-bochum.de

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Karges Group @kargesgroup.bsky.social · May 8

Check out our paper in @inorgchemfront.rsc.org about Utilizing Metal-Metal Electron Transfer in Dinuclear Photosensitizers for Exceptionally High ROS Production. Congrats to @juansanzvi.bsky.social @nmontesdeocas.bsky.social ! Wonderful collaboration with Gustavo Espino! dx.doi.org/10.1039/D5QI...

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Karges Group @kargesgroup.bsky.social · May 6

Time for a new group picture 😉

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Karges Group @kargesgroup.bsky.social · Apr 29

Thanks Conchita!

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Karges Group @kargesgroup.bsky.social · Apr 28

Check out our article in ACS Med. Chem. Lett. @acsmedi.bsky.social about the Induction of Ferroptosis with Au(I) NHC Complexes. Congrats to @nmontesdeocas.bsky.social . Great collaboration with Thomas Scattolin! @ruhr-uni-bochum.de dx.doi.org/10.1021/acsm...

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Karges Group @kargesgroup.bsky.social · Apr 3

Check out our Article in @daltontrans.rsc.org about the Synthesis and Photophysical Evaluation of an Aldehyde Bearing Ru(II) Complex as a Synthetic Precursor for Photodynamic Therapy. Congrats to Lisa, Hung, Nicolas, Zisis, and Eun! dx.doi.org/10.1039/D5DT...

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Karges Group @kargesgroup.bsky.social · Apr 1

Congrats to Pia @psiekierski.bsky.social for receiving the Poster Award of the 19th Ferrocene Colloquium! 🎉

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Karges Group @kargesgroup.bsky.social · Apr 1

Wonderful welcoming you to Bochum and thanks for a fantastic presentation about recent progress in PDT!

joseruizlab.bsky.social @joseruizlab.bsky.social · Apr 1

It was a great pleasure to present our latest results onPDT at the excellent 19th Ferrocene Colloquium at RUB University (Bochum, Germany). Many thanks to the organizers, @NMNLab & @viktoriagessner.bsky.social for the invitation. Thank you also @kargesgroup.bsky.social for the nice collaboration.

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Karges Group @kargesgroup.bsky.social · Mar 22

Thanks Maniklal!

Karges Group @kargesgroup.bsky.social · Mar 21

Check out our article in J. Med. Chem. @acsmedi.bsky.social about the Rational Design of an Ir(III) Complex with Exceptionally Strong Human Serum Albumin Binding for Photodynamic Therapy. Congrats to Antonio & Lisa! Wonderful collaboration with @joseruizlab.bsky.social ! pubs.acs.org/doi/full/10....

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Karges Group @kargesgroup.bsky.social · Feb 23

Das ist Schade, aber viel Spaß in Mainz. Gerne, können wir morgen besprechen. 😉

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Karges Group @kargesgroup.bsky.social · Feb 23

Kannst gerne das nächste Mal in Bochum vorbei kommen. Du bist herzlich eingeladen. Noch eine schöne Nacht und bis Morgen.

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Karges Group @kargesgroup.bsky.social · Feb 23

Ich komme erst morgen früh. Viel Spaß in Münster!

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Karges Group @kargesgroup.bsky.social · Jan 18

Congrats Pepe!

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Reposted by Karges Group

joseruizlab.bsky.social @joseruizlab.bsky.social · Jan 17

A novel arene osmium(ii) complex as an effective rhabdomyosarcoma cancer stem cell agent - now published in InorgChemFront in collaboration with Viktor Brabec pubs.rsc.org/en/content/a... Congrats to all the co-authors.

A novel benzothiazole-1,2,3-triazole-based arene osmium(II) complex as an effective rhabdomyosarcoma cancer stem cell agent

We designed a series of pseudo-octahedral arene Os(ii) complexes (Os1–Os5) with the general formula [(η6-p-cym)Os(BTAT)Cl]+, where BTAT represents chelating N^N′ ligands based on the 1-aryl-4-benzothi...

pubs.rsc.org

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