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Juan Carlos López-Gil

@juancarloslpz13.bsky.social

330 followers 140 following 30 posts

Postdoctoral researcher interested in pancreatic cancer initiation and its microenvironment. Experimental Oncology Lab at CNIO. Former SainzLab (IIBm-CSIC) & La Caixa Fellow.

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Juan Carlos López-Gil @juancarloslpz13.bsky.social · Jan 13

Glad to share with you the latest publication from the Sainz Lab in which I had the chance to participate. Here, we try to reprogram TAMs to difficult the PDAC metastatic process. jnanobiotechnology.biomedcentral.com/articles/10....

Reprogramming tumor-associated macrophages with lipid nanosystems reduces PDAC tumor burden and liver metastasis - Journal of Nanobiotechnology

Background Pancreatic ductal adenocarcinoma (PDAC) requires innovative therapeutic strategies to counteract its progression and metastatic potential. Since the majority of patients are diagnosed with ...

jnanobiotechnology.biomedcentral.com

Reposted by Juan Carlos López-Gil

cniostopcancer.bsky.social @cniostopcancer.bsky.social · Sep 10

Los últimos avances en la investigación del cáncer de páncreas, en un congreso de la @fundacionareces.bsky.social coordinado por Mariano Barbacid y Carmen Guerra, con Francisco X. Real, Núria Malats y Vasiliki Liaki, de #CNIOStopCancer.

🔏Inscripciones gratis online t.co/IRqqi8XfFR

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Reposted by Juan Carlos López-Gil

Instituto de Investigaciones Biomédicas Sols-Morreale (IIBM) @iib.uam.es · Aug 12

El @csic.es difunde la concesión de la ayuda de proyectos sinérgicos de la Comunidad de Madrid a nuestro compañero Dr. Bruno Sainz junto con el Dr. Sergio Serrano-Villar @serranovillar.bsky.social del #IRYCIS
Enhorabuena a los dos grupos de investigadores👏

@dicma-csic.bsky.social

CSIC @csic.es · Aug 5

🔬 El proyecto del @iibm-csic-uam.bsky.social, con el #IRYCIS, investiga sobre el microbioma intestinal de pacientes con respuestas excepcionales a la inmunoterapia

👉 El objetivo final es descubrir fármacos para superar la resistencia en tumores refractarios a inmunoterapia

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Reposted by Juan Carlos López-Gil

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · Aug 4

A TARGETED COMBINATION THERAPY ACHIEVES EFFECTIVE PANCREATIC CANCER REGRESSION AND PREVENTS TUMOR RESISTANCE https://www.biorxiv.org/content/10.1101/2025.08.04.668325v1

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Reposted by Juan Carlos López-Gil

CSIC @csic.es · Aug 5

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Juan Carlos López-Gil @juancarloslpz13.bsky.social · Jul 10

Congratulations Toni and team!! Super cool piece of work. IL1beta always in the spot!!

Reposted by Juan Carlos López-Gil

cniostopcancer.bsky.social @cniostopcancer.bsky.social · Jul 7

Durante la ‘Jornada Amigos y Amigas del CNIO’, el #CNIOStopCancer celebró la solidaridad, clave para atraer talento y avanzar en la investigación del cáncer. Quienes donan se encontraron con quienes investigan, para intercambiar emoción y conocimiento. 🧵

El CNIO celebra la solidaridad de sus Amigos y Amigas, clave para atraer talento y avanzar en la investigación del cáncer

Una parte importante del conocimiento que genera el Centro Nacional de Investigaciones Oncológicas (CNIO), y que se orienta a mejorar la prevención, el diagnóstico y el tratamiento del cáncer, es fruto de la generosidad. La generosidad de las personas, empresas y fundaciones que realizan donaciones al centro a través del programa ‘Amigos/as del CNIO’. Desde que se estableció, en 2015, todos los fondos […]

bit.ly

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Reposted by Juan Carlos López-Gil

cniostopcancer.bsky.social @cniostopcancer.bsky.social · Jul 7

@juancarloslpz13.bsky.social estudia mutaciones en las células madre tumorales del tipo más frecuente y agresivo de cáncer de páncreas, el adenocarcinoma ductal, para lograr un diagnóstico más temprano y contribuir a desarrollar fármacos tanto prevenirlo como para tratarlo mejor.

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Reposted by Juan Carlos López-Gil

PSanchoLab @psancholab.bsky.social · Jul 4

Extremely happy and proud to share with you all our last article in @CR_AACR on the prometastatic role of PPAR-delta in pancreatic cancer. Check it out here:
aacrjournals.org/cancerres/ar...

PPAR-δ Orchestrates a Pro-metastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer

Abstract. The pronounced desmoplastic response in pancreatic ductal adenocarcinoma (PDAC) contributes to the development of a microenvironment depleted of oxygen and nutrients. To survive in this host...

aacrjournals.org

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Juan Carlos López-Gil @juancarloslpz13.bsky.social · Jun 27

Thank you Victor for the kind invitation and the opportunity to talk about my favourite topic!

Victor Javier @vjsanchez.bsky.social · Jun 26

Dr. Juan Carlos Lopez Gil wrapped up with the immune component within the tumor microenvironment. The interplay between cancer cells and immune system is crucial for developing new therapies. Amazing day! 🎯 @juancarloslpz13.bsky.social

Reposted by Juan Carlos López-Gil

Victor Javier @vjsanchez.bsky.social · Jun 26

Day 2 of our pancreatic cancer course was incredible! So excited about the amazing scientific content we covered today. From cancer stem cells to immune microenvironment - what a journey! 🔬✨ 🧪@ufvmadrid.bsky.social

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Juan Carlos López-Gil @juancarloslpz13.bsky.social · Jun 26

Giving talks is one of the parts of this job that I love the most! Today twice. First, for the CNIO Friends initiative which support my postdoctoral work. Later, at Universidad Francisco de Vitoria about immune suppression in PDAC. What a joy to share science!!

Reposted by Juan Carlos López-Gil

Victor Javier @vjsanchez.bsky.social · Jun 25

Amazing first day of our pancreatic cancer summer course! Great attendance with young professionals eager to learn more about this disease - they are the future of better treatments 🔬

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Juan Carlos López-Gil @juancarloslpz13.bsky.social · Jun 17

Fresh from the oven!! Our latest review published in @chp-pivot.bsky.social about the origin of PDAC CSCs and their inner and outer determinants by Diego Navarro and myself. A little bit of inflammation, a little bit of CIN, tons of stemness!! Enjoy!!

www.pivotscipub.com/chp/2/2/0010

Reposted by Juan Carlos López-Gil

VickySanzMoreno @vickysanzmoreno.bsky.social · May 15

Exciting opportunity: Emerging Clinical Academic Fellowship scheme, newly launched by CRIS Cancer Foundation and the ICR
We are offering a project within this scheme, please share!
👇 👇 🤩

www.icr.ac.uk/study-and-ca...

Opportunities for postdoctoral clinical fellows - The Institute of Cancer Research, London

CRIS Cancer Foundation and the ICR are offering 2-3 year fellowships to support the development of outstanding early postdoctoral stage clinical researchers.

www.icr.ac.uk

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Juan Carlos López-Gil @juancarloslpz13.bsky.social · Apr 29

Saying goodbye to beautiful London after a terrific @transpan_cost meeting. So glad to present new data from the Exp Oncology lab and meet old and new friends fighting for new opportunities against PDAC.

Juan Carlos López-Gil @juancarloslpz13.bsky.social · Apr 18

Nice place to retire 🌲🌳

Juan Carlos López-Gil @juancarloslpz13.bsky.social · Apr 10

Two sides of scientific life lately. Yesterday, in the mountains in a bioinformatics retreat organised by CIBERONC, and today, at Fundación Ramón Areces for the CRIS Scientific Symposium.

Reposted by Juan Carlos López-Gil

Cold Spring Harbor Laboratory @cshlnews.bsky.social · Apr 2

Pancreatic cancer is projected to become the second-deadliest cancer by 2030, but new research from CSHL may offer a path forward. Professor David Tuveson & Research Investigator Claudia Tonelli have discovered a way to intercept pancreatic cancer before it fully forms.

In pancreatic cancer, a race against time | Cold Spring Harbor Laboratory

AI generated voice with David Tuveson’s actual voice Pancreatic cancer is projected to become the second-deadliest cancer by 2030. By the time it’s diagnosed, it’s often difficult to treat. So, for bo...

www.cshl.edu

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Reposted by Juan Carlos López-Gil

ASEICA @aseica.bsky.social · Mar 26

📢‼️ Abierta la convocatoria de la VI Ayuda @fundacionfero.bsky.social-ASEICA para el Talento Joven en Cáncer

👨‍🔬🔬80.000€

🎯: Promover la investigación oncológica de personal joven investigador en España

🗓️Revisa los plazos de presentación
➡️ Cierre primera fase: 6/04👇

www.aseica.es/la-fundacion...

La Fundación FERO y ASEICA renuevan su colaboración para apoyar a nuevos grupos de investigación en oncología

Estas entidades convocan una ayuda orientada a jóvenes científicos y científicas que están iniciando sus grupos cualquier ámbito de la investigación en cáncer.La cuantía es de 80.000€ Madrid, marzo...

www.aseica.es

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Reposted by Juan Carlos López-Gil

Denis Wirtz @deniswirtz.bsky.social · Mar 26

Yup

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Reposted by Juan Carlos López-Gil

ASEICA @aseica.bsky.social · Mar 25

🔬¿Eres postdoc e investigas en cáncer?
Te interesa‼️

📢 Isabel Fabregat (@idibell.bsky.social) "Consejos para triunfar en convocatorias postdoctorales de financiación"

📅Mañana miércoles, 26-M, 9h.
📩[email protected]

Coordinan: Sara Manzano & Vanesa Cepas Lopez

#ASEICAJoven

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Reposted by Juan Carlos López-Gil

S. García-Silva @s-garciasilva.bsky.social · Feb 27

The spirit of multidisciplinary work in just one man, Wolfgang von Goethe. Here it is an illustration from Zur Farbenlehre (Theory of Colours).

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Juan Carlos López-Gil @juancarloslpz13.bsky.social · Feb 25

Glad to see this paper in its final version in
@naturecomms.bsky.social. More PGLYRP1 related stuff, this time in macrophages!! Another work highlighting the importance of PGLYRP1 in inflammation and with possible traslation to other diseases. Congrats to the authors! www.nature.com/articles/s41...

PGLYRP1-mediated intracellular peptidoglycan detection promotes intestinal mucosal protection - Nature Communications

Peptidoglycan recognition proteins (PGLYRPs) are implicated in the control of the intestinal microbiota. Here, combining in vitro and in vivo work, the authors show that PGLYRP-1 act as an intracellul...

www.nature.com

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Juan Carlos López-Gil @juancarloslpz13.bsky.social · Feb 24

Guess who’s back? 🔬 #pancreaticcancer

Reposted by Juan Carlos López-Gil

Amaia Cipitria @amaiacipitria.bsky.social · Feb 19

📢 Are you a cancer researcher willing to strengthen ties with Spain? Are you looking for new opportunities or collaboration partners? Or are you in Spain searching for a lab abroad? Then take a look at #ASEICAInternacional and sign up here👇
bit.ly/4geGD0e. Please share the link!
@aseica.bsky.social

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