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Genes & Diseases Journal @genesndiseases.bsky.social · 5h

This study shows that in #testicular #DLBCL, exhausted T cells cluster around #Tumor B cells, encircled by #Macrophages & targeting #TranscriptionFactors E2F & CREB may unlock new avenues for DLBCL intervention. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Genes & Diseases Journal @genesndiseases.bsky.social · 13h

Genes & Diseases invites reviewers with expertise in:
Human genetics & genomics
Cancer biology
Neurological, cardiovascular, and metabolic disorders
Translational medicine and more
Contact us: [email protected]
#Genetics #PeerReview #GenesAndDiseases

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Genes & Diseases Journal @genesndiseases.bsky.social · 13h

Did you know there's a YouTube channel just for Genes & Diseases content?
Subscribe here: www.youtube.com/@GenesNDisea...
#GeneticsResearch #OncologyResearch

Genes & Diseases Journal @genesndiseases.bsky.social · 13h

This study uncovers the oncogenic role of TUG1 in #Chondrosarcoma and its interactions with the downstream regulatory axis, providing novel insights into the tumorigenic mechanisms of CHS. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

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Genes & Diseases Journal @genesndiseases.bsky.social · 17h

This study identifies #CSMD1 as a potentially novel causative gene associated with #DevelopmentalAndEpilepticEncephalopathy and generalized #Epilepsy employing a trio-based whole-exome sequencing approach. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Genes & Diseases Journal @genesndiseases.bsky.social · 1d

A new study highlights a non-canonical role of the S6K1–SGK1 pathway in #Necroptosis during #TBI, identifying it as a promising therapeutic target for TBI and other necroptosis-related conditions. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Genes & Diseases Journal @genesndiseases.bsky.social · 1d

Recent review on #Ferroptosis offers new strategies to reverse #DrugResistance in DigestiveCancers through #GPX4 pathways, #IronMetabolism, and #LipidPeroxidation, paving the way for targeted and combination therapies. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

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Genes & Diseases Journal @genesndiseases.bsky.social · 1d

New research reveals that 8-Cl-Ado inhibits #Hepatocarcinogenesis by suppressing #ADAR1 and regulating PPARγ-driven #LipidMetabolism, offering new #therapeutic targets for #HCC. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Reposted by Genes & Diseases Journal

EANO @eanoassociation.bsky.social · 2d

Still 3 days to #EANO2025 – and here’s another highlight: Maxine Gorter from @amsterdamumc.bsky.social receives the Best Oral Presentation Award in Supportive care & quality of life research. Congrats! 🎉
🧠 OS01 | Fri, Oct 17
👉 Full programme: www.eano.eu/eano2025/pro...
#NeuroOncology #btsm

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Reposted by Genes & Diseases Journal

ESMO - European Society for Medical Oncology @myesmo.bsky.social · 1d

🌱 ESMO is committed to #ClimateConscious #CancerCare .
🧭 The #ESMO4Climate Portal is a central hub of updated, easy-to-navigate resources on #sustainability in oncology, created to serve the #ONEoncologycommunity. #ESMO25
🔗 buff.ly/WmZhoYM

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Reposted by Genes & Diseases Journal

European Society for Radiotherapy and Oncology (ESTRO) @estroradiotherapy.bsky.social · 1d

🧬 ESTRO’s #radiobiology course, held in Rome, offered a deep dive into the biology behind #radiotherapy.
From stem cells to clinical cases, attendees gained practical insights, strengthened their skills, and connected with peers from around the world.
👉 bit.ly/4qaz9Bx #ESTROSchool

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Genes & Diseases Journal @genesndiseases.bsky.social · 2d

The review from @ShanghaiUni_TCM highlights how Lgr6⁺ cells regulate homeostasis & tissue repair across organs, while their abnormal expression drives disease progression, positioning Lgr6 a promising therapeutic target.

#OpenAccess: www.sciencedirect.com/science/arti...

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Genes & Diseases Journal @genesndiseases.bsky.social · 2d

This study highlights the IRP1/ARID3A complex as a potential #Chemotherapy target & its promise in combination with #Ferroptosis inducing drugs for #PancreaticCancer therapy. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Genes & Diseases Journal @genesndiseases.bsky.social · 2d

This recent review explores #CellularSenescence in #IntervertebralDiscDegeneration, summarizing detection methods, #RegulatoryMechanisms, & therapies to inhibit #Senescence, & also addresses the challenges in #Clinical applications. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

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Genes & Diseases Journal @genesndiseases.bsky.social · 2d

MED14 is the largest subunit in the Mediator complex and plays a key role in regulating RNA polymerase II-mediated transcription, but its developmental function remains largely unknown.

Read #openacess article: tinyurl.com/4kaadcfb

Subscribe for research videos: www.youtube.com/@GenesNDisea...

Genes & Diseases Journal @genesndiseases.bsky.social · 2d

This latest study shows that ROS accumulation reduces #OxidativeStress, #Nrf2, IL-6/IL-8, & activates Jak2/Stat3, leading to decreased #Inflammatory cell infiltration, opening new #therapeutic avenues for #ChronicHepatitis. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

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Reposted by Genes & Diseases Journal

ESMO - European Society for Medical Oncology @myesmo.bsky.social · 2d

🤖 #ESMOAI25: Learn how to integrate AI into oncology and deliver better care for your patients
Watch F. André, ESMO President, provide powerful reasons to attend this event.
⏰ Register by 22 October and benefit from advantageous fees. #HealthAI

🔗 buff.ly/Oj0vcJt

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Reposted by Genes & Diseases Journal

International Neuroendocrine Cancer Alliance (INCA) @inca-netcancerday.bsky.social · 2d

Get the newest updates in NEN research from the best NEN researchers - visit INCA’s researcher insights video collection: incalliance.org/researcher-i...
✅Available in English with captions in French, German, Italian, Portuguese and Spanish.
#LetsTalkAboutNETs

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Reposted by Genes & Diseases Journal

EACR - European Association for Cancer Research @helloeacr.bsky.social · 2d

Join us in Berlin on 03-05 Nov 2026 to uncover how chromosomal chaos shapes cancer biology and opens new avenues for clinical intervention!

🚨 Registration and abstract submission for Chromosomes in Crisis is now OPEN: www.eacr.org/conference/chromosomesincrisis2026

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Genes & Diseases Journal @genesndiseases.bsky.social · 3d

This latest study shows that Yanghe Decoction suppresses #Osteosarcoma (OS) cell processes by inducing #Apoptosis, #MitochondrialDysfunction & boosting #cisplatin sensitivity, promising synergistic approaches to OS treatment. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

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Reposted by Genes & Diseases Journal

European Society for Radiotherapy and Oncology (ESTRO) @estroradiotherapy.bsky.social · 5d

📢 The first-ever ESTRO Clinical Workshop is coming to Vienna | 12–13 Mar 2026! Spots are limited—don’t miss out.
📌 Submit your motivational statement by 22 Oct to secure your place.

💻 Apply now 👉 bit.ly/47wlj5G
#ESTROCLIN26 #ClinicalWorkshop #RadiationOncology

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Reposted by Genes & Diseases Journal

EACR - European Association for Cancer Research @helloeacr.bsky.social · 5d

Join our free, open access webinar with the Young European Hematology Association & @yefis-immunology.bsky.social, featuring 3 presentations on CAR T-cells!

📅 19 November 14:00-15:30 CET
🌍 Zoom

us02web.zoom.us/webinar/regi...

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Reposted by Genes & Diseases Journal

Precision Oncology News @preconcnews.bsky.social · 7d

The initiative comprises academic institutions, charities, and companies pursuing a broad range of novel diagnostic and therapeutic approaches.

Irish Precision Oncology Consortium Enters Second Phase With €28M

www.precisionmedicineonline.com

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Genes & Diseases Journal @genesndiseases.bsky.social · 3d

This study examines how CLCA4 regulates remission and #stemness transformation in #ColorectalCancer, emphasizing that modulating stemness through CLCA4 can remodel the #TumorMicroenvironment and enhance #ClinicalOutcomes. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Chloride channel accessory 4 suppresses stem cell-like properties of colorectal cancer and enhances anti-PD-1 immunotherapy

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Genes & Diseases Journal @genesndiseases.bsky.social · 4d

Recent review highlights the role of the #Immunoproteasome in #Diabetes and its associated complications, positioning it a potential target for innovative therapies. #DiabetesResearch #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

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