Lightnews — Scholar-powered news

EGA archive @egaarchive.bsky.social · 12h

🧬💬 Tomorrow, Abeer Fadda, bioinformatics lead at the EGA - @crg.eu team and researcher in the @hereditaryeu.bsky.social project, will be participating in a roundtable on genomic medicine at #RIES2025

Check out the agenda ➡️ forumries.com/programa/

1 3

Reposted by EGA archive

HEREDITARY @hereditaryeu.bsky.social · 1d

✨ Big week ahead for the HEREDITARY project!

🧬 #RIES2025 in La Toja, Galicia on October 15-16 with Abeer Fadda (EGA) and an HEREDITARY stand in the exhibition area.

🧠 #BIDays2025 in Brussels, where HEREDITARY will host a World Café.

🔍 https://acortar.link/zlqN2H

1 1 2

Reposted by EGA archive

EASIGEN @easigen-eu.bsky.social · 6d

🚀 Yesterday we presented #EASIGEN-DS to the Federated Human Data Community of @elixir-europe.org

🎯 Ivo Gut, director of @cnag-eu.bsky.social, shared our vision for designing the European genomics infrastructure 🧬

Big thanks to Teresa D'Altri @egaarchive.bsky.social/@crg.eu for the invitation! 👏

1 3

Reposted by EGA archive

Mallory Freeberg @malloryfreeberg.bsky.social · 6d

Stay updated with the latest EGA news by signing up for the newly launched EGA Newsletter! 🤩

Providing easy access the latest highlights and insights from EGA including about #FederatedEGA, @ga4gh.org engagements, international projects, and more 🙌

✏️ Sign up here: mailchi.mp/4c1f9c3a3030...

EGA archive @egaarchive.bsky.social · 8d

📢 We are excited to announce the incoming launch of the EGA Newsletter!

Sign up now to stay updated on the latest news related to Federated EGA, Beacon, along with highlights and updates on the ongoing projects we are involved in 🙌

👉 mailchi.mp/4c1f9c3a3030...

2 3

EGA archive @egaarchive.bsky.social · 7d

Don't forget to subscribe to get the next newsletter: mailchi.mp/4c1f9c3a3030...

Subscribe to the EGA newsletter

mailchi.mp

EGA archive @egaarchive.bsky.social · 7d

The first EGA newsletter has been released!

🚀 Explore the #FederatedEGA timeline
🔎 Discover the EGA Allele Frequency Browser
💥 Check out the projects starting in 2025

And much more! Read the full newsletter here: mailchi.mp/dd9d965ca3a2...

1 3 6

Reposted by EGA archive

Global Alliance for Genomics and Health @ga4gh.org · 7d

Welcome to the start of the GA4GH Connect meeting!

Over the next three days, we will hold 30 collaborative sessions to advance GA4GH standards development and implementation, share insights and best practices, and brainstorm strategic actions as a community.

Join a session:

Connect (8 to 10 October)

Connect agenda (8 to 10 October)

buff.ly

1 2

EGA archive @egaarchive.bsky.social · 8d

📢 We are excited to announce the incoming launch of the EGA Newsletter!

Sign up now to stay updated on the latest news related to Federated EGA, Beacon, along with highlights and updates on the ongoing projects we are involved in 🙌

👉 mailchi.mp/4c1f9c3a3030...

2 4

Reposted by EGA archive

Global Alliance for Genomics and Health @ga4gh.org · 9d

Welcome to day one of the GA4GH 13th Plenary meeting. We are excited to welcome attendees and viewers from around the globe.

Our Plenary live stream starts in one hour. Visit the GA4GH YouTube Channel to tune in to today’s programme:

GA4GH

Global Alliance for Genomics & Health (GA4GH) is a policy-framing and technical standards organization, working together for responsible, voluntary & secure sharing of genomic & clinical data for…

buff.ly

4 3

Reposted by EGA archive

Global Alliance for Genomics and Health @ga4gh.org · 21d

🌐 Join the next GA4GH Beacon Implementers Forum meeting on Wednesday, 26 November at 14:00 UTC.

Learn more and register for the invite:

Beacon Implementers Forum

The GA4GH Beacon Implementers Forum aims to foster knowledge sharing and cross-community collaboration to support the integration and innovation of Beacon in research and clinical genomics. While…

buff.ly

1 2

EGA archive @egaarchive.bsky.social · Sep 15

As part of the research, some of their sequencing data were deposited at the EGA. In this conversation, we explore their experience with data sharing 💡

Check out the interview in our latest blog post: blog.ega-archive.org/from-researc...

From research to data sharing: exploring EGA user's experiences

blog.ega-archive.org

EGA archive @egaarchive.bsky.social · Sep 15

To bridge this gap, we have talked with the Cell Plasticity and Regeneration Group at @idibell.bsky.social after their recent publication of the paper "Mucosal Macrophages Govern Intestinal Regeneration in Response to Injury" in Gastroenterology

🔗 www.gastrojournal.org/article/S001...

Mucosal Macrophages Govern Intestinal Regeneration in Response to Injury

Macrophages regulate the recovery from radiation-induced enteritis by promoting intestinal stem cell regeneration, suggesting potential therapeutic targets to improve the quality of life for cancer pa...

www.gastrojournal.org

1

EGA archive @egaarchive.bsky.social · Sep 15

📣 New blog post alert!

This year, over 400 publications have cited data stored at the EGA, either for deposit or reuse. As a result, we are usually in contact with hundreds of users, but the truth is that we don't know as much about you as we would like!

1

EGA archive @egaarchive.bsky.social · Aug 14

📍 The SOX11:SMARCA4 complex is a driver of oncogenic transcriptional programs in mantle cell lymphoma
📃 Published in Blood Cancer Journal @nature.com
🤝 Reused data: EGAS00001004165 & EGAS00001006613
🔗 www.nature.com/articles/s41...

The SOX11:SMARCA4 complex is a driver of oncogenic transcriptional programs in mantle cell lymphoma - Blood Cancer Journal

Blood Cancer Journal - The SOX11:SMARCA4 complex is a driver of oncogenic transcriptional programs in mantle cell lymphoma

www.nature.com

EGA archive @egaarchive.bsky.social · Aug 14

📍 Tumor-associated neutrophil precursors impair homologous DNA repair and promote sensitivity to PARP inhibition
📃Published in Nature Communications
🤲 Deposited data: EGAS00001008154
🔗 www.nature.com/articles/s41...

Tumor-associated neutrophil precursors impair homologous DNA repair and promote sensitivity to PARP inhibition - Nature Communications

Tumor-associated neutrophils exhibit heterogeneity in breast cancer. Here, the authors identify a distinct precursor population (PreNeu) in estrogen receptor-positive tumors. PreNeu suppress homologou...

www.nature.com

1

EGA archive @egaarchive.bsky.social · Aug 14

📍 Chronological age estimation from human microbiomes with transformer-based Robust Principal Component Analysis
📃 Published in Communications Biology @natureportfolio.nature.com
🤝 Reused data: EGAS00001005020
🔗 www.nature.com/articles/s42...

Chronological age estimation from human microbiomes with transformer-based Robust Principal Component Analysis - Communications Biology

An interpretable Transformer-based model accurately predicts chronological age across body site and identifies key microbial signatures of aging.

www.nature.com

1

EGA archive @egaarchive.bsky.social · Aug 14

📍 Targeting FGFR4 abrogates HNF1A-driven metastasis in pancreatic ductal adenocarcinoma
📃 Published in Molecular Cancer @springernature.com
🤝 Reused data: EGAS00001002543
🔗 molecular-cancer.biomedcentral.com/articles/10....

Targeting FGFR4 abrogates HNF1A-driven metastasis in pancreatic ductal adenocarcinoma - Molecular Cancer

Background We previously identified an oncogenic role for the transcription factor HNF1A in pancreatic ductal adenocarcinoma (PDAC). However, the role of HNF1A in the metastatic progression of PDAC re...

molecular-cancer.biomedcentral.com

1

EGA archive @egaarchive.bsky.social · Aug 14

📍 Detection of Brain Cancer Using Genome-wide Cell-free DNA Fragmentomes
📰 Published in Cancer Discovery @theaacr.bsky.social
🤝 Reused data: EGAS00001007249
🤲 Deposited data: EGAS50000000986
🔗 aacrjournals.org/cancerdiscov...

Detection of Brain Cancer Using Genome-wide Cell-free DNA Fragmentomes

A machine learning approach leveraging genome-wide cfDNA fragmentation profiles enables noninvasive detection of gliomas, capturing signals from tumor-derived DNA and changes in immune cell population...

aacrjournals.org

1

EGA archive @egaarchive.bsky.social · Aug 14

Data reuse can boost the potential of any dataset, even during summer 😎☀️! From time to time, we highlight some of the latest papers featuring deposited data at the EGA or reused data from the Archive 👀

Check out our latest compilation 🧵↘️

1 2 3

Reposted by EGA archive

EASIGEN @easigen-eu.bsky.social · Aug 5

💡Did you know? The EGA stores 15+ PB of biomedical data from 20+ countries, spanning studies on cancer, neurodegeneration, and more. As of 2025, over 400 publications have cited its 12,000 datasets for research and reuse.

🔔 𝐒𝐭𝐚𝐲 𝐭𝐮𝐧𝐞𝐝 𝐭𝐨 𝐦𝐞𝐞𝐭 𝐭𝐡𝐞 𝐞𝐧𝐭𝐢𝐫𝐞 𝐂𝐨𝐧𝐬𝐨𝐫𝐭𝐢𝐮𝐦!

#EASIGEN #CRG #HorizonEU

1 1

Reposted by EGA archive

EASIGEN @easigen-eu.bsky.social · Aug 5

🔬 CRG co-hosts the @egaarchive.bsky.social with EMBL-EBI, supporting secure storage and sharing of sensitive biomedical data. CRG team has expertise in different areas:

🔹Genomic data management
🔹Bioinformatics infrastructure and tools
🔹ELSI
🔹Collaborative research and innovation

1 1 2

Reposted by EGA archive

EASIGEN @easigen-eu.bsky.social · Aug 5

📢 Meet the partners of the #EASIGEN-DS Consortium!

📍 @crg.eu is a biomedical research hub driving innovation in life sciences. Based at the PRBB, they specialise in genomics, systems biology, and computational biology. In #EASIGEN-DS, they serve as the expert node for data and data management

1 1 1

Reposted by EGA archive

Ewan Birney @ewanbirney.bsky.social · Jul 21

Excellent news, and shows the progress - and flexibility - of FEGA in providing a mechanism for federated discovery and access of controlled access human genomic data, consistent with national legislation and ethics.

SIB Swiss Institute of Bioinformatics @sib.swiss · Jul 21

🎉🧬🇨🇭 Researchers in Switzerland can soon deposit human genomics data in a secure national archive, and control access to researchers around the world, with Swiss FEGA joining the international FEGA network 👇

Swiss FEGA is consortium of six institutions, including at @ethz.ch, coordinated by SIB.

Switzerland joins the Federated European Genome-phenome Archive (FEGA)

Following the successful demonstration of secure infrastructure for storing and sharing sensitive patient data, Switzerland has now officially joined the Federated European Genome-phenome Archive (FEG...

www.sib.swiss

1 9

EGA archive @egaarchive.bsky.social · Jul 21

With the signing, the network now comprises 9 national nodes, hosting a total of 37 federated datasets available for reuse 🚀🧬 If you are looking for information on how to join the #FederatedEGA, take a look here:

👉 ega-archive.github.io/FEGA-onboard...

Establishing a Federated EGA Node - FEGA Onboarding Knowledge base

Knowledge base for Onboarding Federated EGA nodes.

ega-archive.github.io

1 3

EGA archive @egaarchive.bsky.social · Jul 21

We are celebrating the joining of Switzerland to #FederatedEGA as a national node, after the signature of the Collaboration Agreement with the @sib.swiss!

More information ↘️ www.sib.swiss/news/switzer...

Switzerland joins the Federated European Genome-phenome Archive (FEGA)

Following the successful demonstration of secure infrastructure for storing and sharing sensitive patient data, Switzerland has now officially joined the Federated European Genome-phenome Archive (FEG...

www.sib.swiss

1 1 6