Author | Lightnews

Enrique de-Madaria @demadaria.bsky.social · 19d

9 years in 7 minutes

How does it feel when, after 9 years of work, a clinical trial like SIMBA is presented for 7 minutes at a conference?
#UEGweek #Berlin

Don't miss the latest post on my blog #DeMadariaVsPlacebo

demadaria.substack.com/p/9-years-in...

9 years in 7 minutes

9 años en 7 minutos

demadaria.substack.com

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Reposted by Enrique de-Madaria

United European Gastroenterology @myueg.bsky.social · 26d

Congratulations to our newly elected council members:

Silvio Danese, Vice President
@iagorlago.bsky.social, Chair Elect Education Committee

Chloé Melchior, Research Committee Chair
@demadaria.bsky.social, Independent Councillor

We are looking forward to working with you!

eine Gruppe von Menschen steht in einem Flur

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Enrique de-Madaria @demadaria.bsky.social · Sep 14

Don't miss the latest post on my clinical research blog #DeMadariaVsPlacebo

The Difficult Decision of the Daruma's Eye

When you have to decide which exciting project to focus on

demadaria.substack.com/p/the-diffic...

The Difficult Decision of the Daruma’s Eye

La difícil decisión del ojo del Daruma

demadaria.substack.com

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Enrique de-Madaria @demadaria.bsky.social · Aug 31

Best of @myueg.bsky.social session during the Panamerican Gastroenterology week in Lima, Peru #SPED2025 @maloehr.bsky.social

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Enrique de-Madaria @demadaria.bsky.social · Aug 10

Don't miss the new post on my blog DeMadaria Vs Placebo.

Following the success of How to Get Your Article Rejected and 10 Tricks to Be a Terrible Mentor, here comes How to Fail in Your Collaborative Study.

demadaria.substack.com/p/how-to-mak...

How to make your collaborative clinical study fail

Como conseguir que tu estudio clínico colaborativo fracase

demadaria.substack.com

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Enrique de-Madaria @demadaria.bsky.social · Aug 7

Should GI bleeding/altered mental status be considered organ failure in acute pancreatitis? Pancreatology

Our latest publication: This study evaluates the independent associations of GIB and IMS with morbidity and mortality in AP

authors.elsevier.com/a/1lYrs53tct...

authors.elsevier.com

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Enrique de-Madaria @demadaria.bsky.social · Aug 3

Final days for Early Bird Registration!

Join the Harvard postgraduate course on pancreatic diseases and bring Harvard to your CV

Learn the best and discover brand-new lectures not included in previous editions

open.substack.com/pub/demadari...

Bring Harvard to your CV! Last days for early bird registration

Lleva a Harvard a tu CV

open.substack.com

Enrique de-Madaria @demadaria.bsky.social · Jul 27

There is a drug called ursodeoxycholic acid that dissolves gallstones. Urso means “bear” in Latin. Why is it called that?

Why does our OSOPOLAR (POLAR BEAR) clinical trial have that name?

Read my latest blog post
👇🏻👇🏻👇🏻
demadaria.substack.com/p/bile-from-...

Bile from polar bears

La bilis de los osos polares

demadaria.substack.com

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Enrique de-Madaria @demadaria.bsky.social · Jun 6

Nice abdominal X-ray

Chris Ratzlaff @ratzlaff.bsky.social · Jun 6

Amazing mammatus in the sky over my home last night!

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Reposted by Enrique de-Madaria

ammer-herrmenau.bsky.social @ammer-herrmenau.bsky.social · May 10

🥳👉Very happy to share our latest paper published in Endoscopy

🙌Great team effort from 17 🇪🇺centers

PPI 💊 intake lead to ↗️ LAMS occlusion and ↗️ necrosectomy rates addressing WONs but 🩸complication same as No PPI

What is your practice?

tinyurl.com/2ubsu5u4

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Enrique de-Madaria @demadaria.bsky.social · May 4

I particularly love the corn-pancreas

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Enrique de-Madaria @demadaria.bsky.social · May 4

How and when do we become infected with Helicobacter pylori?

From my blog for patients "The Pitch of The Stomach"

thepitofthestomach.substack.com/p/how-and-wh...

How and when do we become infected with Helicobacter pylori?

H. pylori: The Most Common Chronic Infection in Humans — But How Do We Catch It?

thepitofthestomach.substack.com

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Enrique de-Madaria @demadaria.bsky.social · Apr 27

Just published in @UEGJournal : “How to Survive and Succeed in the Design and Execution of a Collaborative Randomized Controlled Trial”

There you have all the tricks I've learned over the last 15 years about how to conduct a multicenter RCT

All🦾

onlinelibrary.wiley.com/doi/10.1002/...

How to Survive and Succeed in the Design and Execution of a Collaborative Randomized Controlled Trial

This article guides the design and execution of successful collaborative randomized controlled trials (RCTs). Aimed at researchers looking to impact clinical practice, it highlights the advantages of....

onlinelibrary.wiley.com

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Enrique de-Madaria @demadaria.bsky.social · Apr 24

3/3
This is a very special study for me, as I received the @myueg.bsky.social Research Prize for this project.

Many thanks to all the contributors who have worked so efficiently and passionately!

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Enrique de-Madaria @demadaria.bsky.social · Apr 24

2/3
With a total of 792 patients from 43 centers across 18 countries from the 5 continents were included in the WATERLAND trial, making it the largest and most globally representative randomized clinical trial conducted in acute pancreatitis to date.

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Enrique de-Madaria @demadaria.bsky.social · Apr 24

1/3
The abstract with the results of WATERLAND, an RCT comparing lactated Ringer's solution vs. normal saline in fluid therapy for acute pancreatitis, has just been submitted to the UEG Week Berlin October 25 @myueg.bsky.social

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Enrique de-Madaria @demadaria.bsky.social · Apr 18

3/3

We have worked hard on this new edition, we will deal with new topics on September 26th and 27th, all online and with 3 months to watch the talks, soon we will give you more information.

Enrique de-Madaria @demadaria.bsky.social · Apr 18

2/3

The first edition was a success, almost 500 people registered from 50 countries, with talks by 34 international experts in pancreatology with the aim of improving your clinical practice

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Enrique de-Madaria @demadaria.bsky.social · Apr 18

1/3

Very good news: the second edition of the course "Management of Pancreatic Disorders for the Practicing Clinician" co-directed by Yasmin Hernandez-Barco and myself has just been approved by @harvard.edu

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Reposted by Enrique de-Madaria

jalcedo.bsky.social @jalcedo.bsky.social · Apr 14

¿Será iluminar el estómago una buena estrategia para tratar la gastroparesia?
Resumimos los resultados de un estudio al respecto y su traslación a la práctica clínica
👇👇👇👇
doi.org/10.1111/nmo....

Direct Stimulation of Gastric Smooth Muscle Cells via Gq Proteins With Light

Optogenetic stimulation enables direct and selective stimulation of smooth muscle cells and thus provides a new opportunity to restore gastric contractility in cases of gastroparesis. Herein, we demo...

doi.org

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Enrique de-Madaria @demadaria.bsky.social · Apr 9

Participating in Chronicity Forlì 2025 invited by my friend Carlo Fabbri #EmiliaRomagna

Great talks on promotion of research, basic research in pancreatic cancer.

Sharing a nice experience with Carlo's team Chiara, Cecilia, Stefano, Andrea...

Enrique de-Madaria @demadaria.bsky.social · Apr 6

In Seoul they give fluid resuscitation to pine trees, I wonder if it is aggressive or moderate

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Enrique de-Madaria @demadaria.bsky.social · Apr 5

Proud to receive the prize for the best oral presentation of the International Biliary Pancreatic Meeting 2025 in Seoul, validation of PAN-PROMISE score for its application in RCTs in acute pancreatitis
Thanks to the scientific committee!

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Reposted by Enrique de-Madaria

Matthias Löhr ʚїɞ @maloehr.bsky.social · Apr 5

… and so the story continues @demadaria.bsky.social presenting the #Waterfinder study in #acutepancreatitis as a follow-up to the #Waterfall trial to find the optimal fluid resuscitation

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Reposted by Enrique de-Madaria

United European Gastroenterology @myueg.bsky.social · Apr 4

Submit your abstract to UEG Week 2025!

Present your research at one of Europe’s largest and most influential congresses in gastroenterology – where science meets a truly multidisciplinary and diverse audience from around the world.

📝 Submit your abstract by April 25!
https://bit.ly/3WODJci

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