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Davi Bock

@dddavi.bsky.social

2.1K followers 440 following 300 posts

Rural neuroscientist. Connectomics. Protists. caveat emptor: https://bsky.app/profile/dddavi.bsky.social/post/3k5bnogiq5r2j

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Davi Bock @dddavi.bsky.social · Oct 2

Hard to overstate how pleased I am that the FlyWire consortium converted our FAFB ("Full Adult Fly Brain") EM volume into a connectome, and that the resulting science has been (and will be) so impactful. Thanks to everyone involved. #neuroscience www.nature.com/immersive/d4...

The FlyWire connectome: neuronal wiring diagram of a complete fly brain

Artificial intelligence and human expertise meet to generate a map of all the connections in the fly brain. The resource is already being used by experimentalists and theoreticians to further our unde...

www.nature.com

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Reposted by Davi Bock

Grace Lindsay @neurograce.bsky.social · 4d

That's what we're saying people should try to do here: www.sciencedirect.com/science/arti...

Testing methods of neural systems understanding

Neuroscientists apply a range of analysis tools to recorded neural activity in order to glean insights into how neural circuits drive behavior in orga…

www.sciencedirect.com

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Davi Bock @dddavi.bsky.social · 6d

Interesting answer from Mark to a question I had about his piece on recurrence and active filtering in sensory cortex (at www.annualreviews.org/content/jour...)

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Davi Bock @dddavi.bsky.social · 6d

thanks for the answer, interesting overall, + interesting to think about "comparative recurrence" as a target of study..

Davi Bock @dddavi.bsky.social · 6d

🤚❓Massive recurrence is not unique to cortex but rather permeates the CNS of all animals studied so far. How do you think about this? Maybe you would argue that active filtering in cortex is a special use of recurrence? Or maybe the converse, that active filtering happens everywhere?

& hi Mark :)

Reposted by Davi Bock

Steven Cook @dumpyunc.bsky.social · 7d

Our group at the Allen Institute is recruiting a technician and postdoc to work on light microscopy-based connectomics. Please DM me or share with anyone you think may be interested in this NIH BRAIN CONNECTS funded project.

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Davi Bock @dddavi.bsky.social · 7d

😂

Davi Bock @dddavi.bsky.social · 7d

Half!? I'm impressed you give it that much! :)

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Davi Bock @dddavi.bsky.social · 7d

I love this piece!

It shows the many ways a connectome can be put to use, AND the many complementary modalities that are needed, beyond the connectome, to answer real questions.

And it makes me feel good about having helped to generate the thing. :)

The Transmitter @thetransmitter.bsky.social · 8d

To celebrate the first anniversary of the release of FlyWire, we asked nine neuroscientists to share how they are using connectome data in their research and what they hope is in store for the future of fly connectomics.

By @franciscorr25.bsky.social

#neuroskyence

bit.ly/3Wx5nt3

How FlyWire is redefining Drosophila research, one year in

Nine Drosophila researchers share how the connectome transformed the field and what additional new tools they would like to see.

bit.ly

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Reposted by Davi Bock

Philip Hubbard @philiphubbard.bsky.social · 9d

Rendering this video was a nice test for #Blender3d, as the full set of bodies visible by the end involved almost 1.1 billion polygons. It all worked out well on our H200 cluster.

Janelia Research Campus @hhmijanelia.bsky.social · 9d

🪰 A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the millions of connections between them.
🔗 https://hhmi.news/4o3EJnk

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Reposted by Davi Bock

Greg Jefferis @jefferis.bsky.social · 9d

Exciting news for #drosophila #connectomics and #neuroscience enthusiasts: the Drosophila male central nervous system connectome is now live for exploration. Find out more at the landing page hosted by our Janelia FlyEM collaborators www.janelia.org/project-team....

Male CNS Connectome

A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...

www.janelia.org

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Davi Bock @dddavi.bsky.social · 11d

Nice. And I bet with a loupe you could see synapses in the prints. :) What paper is this from?

Reposted by Davi Bock

Ignacio Arganda-Carreras @iarganda.bsky.social · 15d

📣 We’re hiring, please RT! Fully funded 4-year PhD position in our CVPD group at @informatikaehu.bsky.social!

Research at the intersection of AI, deep learning & bioimage analysis. 🧠🔬

📅 Applications open Oct 6 (deadline: ~Oct 27)
📍 San Sebastian, Spain.
👉 cvpd.github.io/post/2025-09...

📢 Open 4-year PhD Position in Deep Learning for Bioimage Analysis! | CVPD Research group

The Computer Vision and Pattern Discovery (CVPD) group at the University of the Basque Country (UPV/EHU) is offering a fully funded 4-year PhD position within the recently awarded project TOSBI: Towar...

cvpd.github.io

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Reposted by Davi Bock

Andrew Dacks @adacks.bsky.social · 15d

Case Western Reserve Department of Biology is hiring! We're recruiting for a tenure-track position focusing on eukaryotic microbiology, especially microbial/environment interactions. Please share widely: apply.interfolio.com/174456

Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

apply.interfolio.com

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Davi Bock @dddavi.bsky.social · 15d

Beautiful light this morning on my walk to the EMBL Heidelberg campus

morning light through rising fog in beech woods above Heidelberg, Germany

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Reposted by Davi Bock

Javier Apfeld @javierapfeld.bsky.social · Nov 28

I am so happy this perspective was published today, on Thanksgiving day!! 🥂🦃

I reflect on how keeping in touch with a field I left behind long ago continues to bring me joy and fulfillment.

Keeping in touch with the road not taken

Nature Structural & Molecular Biology - Keeping in touch with the road not taken

www.nature.com

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Reposted by Davi Bock

Aaron Kerlin @kerlinaaron.bsky.social · 21d

Our new preprint!: arxiv.org/abs/2509.18399
Imaging fast glutamate or voltage sensors?
New method to amplify electro-optical deflectors enables MHz line rate imaging. No new laser required. Led by @clwarkentin.bsky.social & @hari-shankar.bsky.social. MHz random-access imaging is in the works…

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Davi Bock @dddavi.bsky.social · 16d

Pogo, by Walt Kelly: "We have met the enemy and he is us."

Davi Bock @dddavi.bsky.social · 19d

awesome, well done Jeremy!

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Reposted by Davi Bock

Maria Paz Fernandez @mariadelapax.bsky.social · 22d

Ed Kravitz passed away yesterday.
He was a remarkable scientist and mentor- brilliant, curious, creative, and kind. I am grateful to have learned from him. His legacy will endure through his science and through the many people he inspired.

We will miss you, Ed.

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Reposted by Davi Bock

Dan Garisto @dangaristo.bsky.social · 26d

Per NSF staff, the solicitation was cleared in the system, and should have posted automatically on the next business day. So it is being manually held—there's not some kind of logistical issue. Unclear what the rationale for this is.

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Reposted by Davi Bock

Grace Lindsay @neurograce.bsky.social · 29d

I don't know that it works perfectly, but I have to say that the Asta search tool from @ai2.bsky.social is exactly what I want from an AI-powered research search tool for scientists: Describe a style of experiment or work and see if there are papers that have done that.
asta.allen.ai/chat

Ai2 Asta

asta.allen.ai

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Davi Bock @dddavi.bsky.social · 29d

Synaptic connectomes also look like this. Protein & gene interaction networks as well. Fractal recurrence across scales, from brain regions all the way down to molecules -- essential to biological information processing, yet so poorly understood.

Reposted by Davi Bock

Ivan Radin @radinbio.bsky.social · Sep 15

Do you know what happens when you touch a carnivorous sundew plant?
If the touch is strong and large enough, a cytosolic calcium wave will spread from the site of touch throughout the whole plant, but if you only touch one tentacle (see post below), the calcium wave will be local and less intense.

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Davi Bock @dddavi.bsky.social · 29d

lovely whole-cell reconstructions of recorded cells using juxtacellular neurobiotin fill

Tim Viney @vineytj.bsky.social · 29d

*New preprint from the lab* – “Granularity of thalamic head direction cells”
doi.org/10.1101/2025...
🧠📈 🧪
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Granularity of thalamic head direction cells

Head direction signaling is fundamental for spatial orientation and navigation. The anterodorsal nucleus of the thalamus (ADn) contains a high density of head direction (HD) cells that process sensori...

doi.org

Reposted by Davi Bock

Piali Sengupta @senguptalab.bsky.social · Sep 13

Whoa - neuronal ciliary proteome! Tons to dig into here - different from kidney cilia proteome (perhaps unsurprising) and enriched for many postsynaptic proteins, strengthening previous suggestions of cilia as postsynaptic signaling structures.
@nachury.bsky.social
www.biorxiv.org/content/10.1...

In situ Proteomics Unveils Specialized Domains for Extrasynaptic Signaling on Neuronal Cilia

Neuronal cilia have emerged as crucial signaling hubs, yet their molecular composition and integration with synaptic communication remain poorly understood. Using a newly developed Arl13b-TurboID mous...

www.biorxiv.org

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