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Chris van der Gast @chrisvandergast.bsky.social · 4d

The above is either the journal/publisher’s system issue or it’s a handling editor just not engaging their brain. Either way it is a very poor approach to peer review that clearly doesn’t value the reviewer. And if that is the case…

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Chris van der Gast @chrisvandergast.bsky.social · 6d

Got an invite to review a paper on Friday night from a well-known clinical journal. Followed by an abrupt & demanding reminder early Sunday morning

I wonder why it is increasingly difficult to get willing quality reviewers these days?🤷‍♂️

Unsurprisingly I declined the offer to review

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Chris van der Gast @chrisvandergast.bsky.social · Sep 16

Great to be in Queen's Univerity Belfast for the GRAMPUS-CF conference

This @cysticfibrosis.org.uk funded Strategic Research Centre is exploring ‘clusters’ of gut symptoms in #CysticFibrosis to see if they have common causes

More details on GRAMPUS #CF ⬇️ www.grampus-cf.org

GRAMPUS-CF | Discover Gut Insights Today

Join the GRAMPUS-CF study to explore gut symptoms in cystic fibrosis and help develop personalized treatments. Enroll online or via CF centers.

www.grampus-cf.org

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Chris van der Gast @chrisvandergast.bsky.social · Aug 1

Our new paper out in Microbiology Spectrum:

Nontuberculous mycobacteria remodel lung microbiota in #cysticfibrosis associated respiratory infections

Driven by @dwrivett.bsky.social and Michelle Hardman.

From Michelle’s @cysticfibrosis.org.uk funded PhD work

#CF

doi.org/10.1128/spec...

Nontuberculous mycobacteria remodel lung microbiota in cystic fibrosis-associated respiratory infections | Microbiology Spectrum

The influence of NTM infection in pwCF is still debated, and the extent of their contribution to mortality and morbidity is still questioned. Findings in this study highlight a link between the presen...

doi.org

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Chris van der Gast @chrisvandergast.bsky.social · Jun 7

Our new paper out now in Microbiome: Species turnover within #cysticfibrosis lung microbiota is indicative of acute pulmonary exacerbation onset

doi.org/10.1186/s401...

#CF #microbiomeecology #microbiome

Species turnover within cystic fibrosis lung microbiota is indicative of acute pulmonary exacerbation onset - Microbiome

Background Acute pulmonary exacerbations (PEx) are associated with increased morbidity and earlier mortality for people living with cystic fibrosis (pwCF). The most common causes of PEx in CF are by b...

doi.org

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Chris van der Gast @chrisvandergast.bsky.social · Jun 5

Our very own @hgavillet.bsky.social giving her talk today at #ECFS2025 in Milan on the impact of #kaftrio CFTR modulator therapy on the #CysticFibrosis lung microbiome

Our KAFPATH-CF study is a multi-national (UK, USA, & Canada) multi-centre long-term longitudinal study of adults with #CF

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Chris van der Gast @chrisvandergast.bsky.social · Jun 5

Our very own Ryan Marsh presenting his #CysticFibrosis gut microbiome & metabolomics data at the #ECFS2025 meeting in Milan

This is part of the wider @cysticfibrosis.org.uk funded GRAMPUS-CF strategic research centre

👀 here for more details www.grampus-cf.org

Chris van der Gast @chrisvandergast.bsky.social · May 1

Fascinating and important study. May well be transformative in treatment of stubborn chronic lung infections such as by Pseudomonas aeruginosa in #cysticfibrosis and beyond

rdcu.be/ekdWf

Personalized inhaled bacteriophage therapy for treatment of multidrug-resistant Pseudomonas aeruginosa in cystic fibrosis

Nature Medicine - A novel personalized phage therapy strategy that selects phages for a predicted evolutionary trade-off may represent a viable alternative approach for the treatment of...

rdcu.be

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Chris van der Gast @chrisvandergast.bsky.social · Mar 29

Ryan Marsh from my group giving a great talk on our initial #CysticFibrosis gut microbiome findings from our GRAMPUS-CF strategic research centre @ the #ECFS Basic Science meeting in Italy

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Chris van der Gast @chrisvandergast.bsky.social · Feb 28

Final day of the European Young Investigators Meeting #EYIM for #cysticfibrosis in Paris

Delighted to be supporting as a ‘senior’ scientist

The #EYIM2025 presentations have been outstanding

The talent displayed at this meeting bodes well for future of #CF research

Chris van der Gast @chrisvandergast.bsky.social · Feb 4

Helen giving her Rising Star talk @ the #RTI2025 meeting in Glasgow ⭐️

@hgavillet.bsky.social #CF #CysticFibrosis

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Chris van der Gast @chrisvandergast.bsky.social · Jan 16

What a a great place to meet & talk on new #cysticfibrosis respiratory & gut studies with the lovely folk from Manchester Paediatric #CF centre

Feeling genuinely inspired

Whitworth Art Gallery - Manchester

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Chris van der Gast @chrisvandergast.bsky.social · Jan 10

Helen a PDRA in my lab @northumbriauni.bsky.social has been recognised with the Rising Star award @ the upcoming Respiratory Infections Forum #RTI2025.

Well done Helen, what a great recognition!

rti-forum.org/2025/
@lenagroup4resp.bsky.social

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Chris van der Gast @chrisvandergast.bsky.social · Dec 14

Ah, the glamour of international travel. This red eye flight is so early I had to get up half an hour before I went to bed.

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Chris van der Gast @chrisvandergast.bsky.social · Nov 27

…. in Dartmouth 😂

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Chris van der Gast @chrisvandergast.bsky.social · Nov 27

That paper would be old enough to buy me and you a beer 🍺🍺😄

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Chris van der Gast @chrisvandergast.bsky.social · Nov 25

Microbiome ecology approaches reveal bacterial interactions underpin worse lung function in #CysticFibrosis

#CF Lung infections are not caused by 1 pathogen in isolation but instead by interplay of complex lung microbiota of many different microbes interacting with each other & the lung environment

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Chris van der Gast @chrisvandergast.bsky.social · Nov 23

GI pathophysiology and Gut microbiome. Survey closed hence posting.

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Chris van der Gast @chrisvandergast.bsky.social · Nov 22

Thanks Fabrice!

Chris van der Gast @chrisvandergast.bsky.social · Nov 22

Fantastic to see our latest paper now published in mBio on how species interactions impact #cysticfibrosis respiratory infections ⤵️

#microbiomeecology #cf

Lovely way to finish the week

doi.org/10.1128/mbio...

Bacterial interactions underpin worsening lung function in cystic fibrosis-associated infections | mBio

Research studies have repeatedly demonstrated that chronic lung infection in cystic fibrosis is polymicrobial and consequently does not adhere to the single microbe-based Koch’s postulates. Despite th...

doi.org

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Chris van der Gast @chrisvandergast.bsky.social · Nov 14

I think it is @dralirobb.bsky.social. But I’ve been here like two minutes and am also trying to figure out what works 😄

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Reposted by Chris van der Gast

Nick Loman @pathogenomenick.bsky.social · Nov 11

After editing, this very short letter to New Scientist is even shorter now. But I think it gets the point across! @faecalmatters.bsky.social

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Chris van der Gast @chrisvandergast.bsky.social · Nov 13

That would be great. The other place is dying on its backside now

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Chris van der Gast @chrisvandergast.bsky.social · Nov 13

Our latest paper now published in Journal of #cysticfibrosis

Impact of extended Kaftrio therapy on the gut #microbiome in #cf

Great work from Ryan Marsh (not yet in this place)

sciencedirect.com/science/arti...

Impact of extended Elexacaftor/Tezacaftor/Ivacaftor therapy on the gut microbiome in cystic fibrosis

There is a paucity of knowledge on the longer-term effects of CF transmembrane conductance regulator (CFTR) modulator therapies upon the gut microbiom…

sciencedirect.com

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