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Meg Davis @brainsrus.bsky.social · 3d

www.sciencedirect.com/science/arti...

Neurotoxic effects of chronic ethanol on cholinergic interneurons in the dorsomedial striatum

Alcohol use disorder (AUD) has severe adverse health and economic impacts totaling over $240 billion in the U.S. annually. Despite this, FDA approved …

www.sciencedirect.com

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Reposted by Meg Davis

neurosalinas.bsky.social @neurosalinas.bsky.social · 27d

If you're interested in Parkinson's disease or dietary interventions for PD, check out this podcast where we discuss our recent EJN article.

FENS-EJN Journal club Episode 1: Mitochondria, Ketones & Dopamine with Vikrant Mahajan and Armando Salinas
www.podbean.com/ew/pb-ikekv-...

FENS-EJN Journal club Episode 1: Mitochondria, Ketones & Dopamine with Vikrant Mahajan and Armando Salinas

Kicking off the FENS-EJN Journal Club podcast, host Dr Matteo Piumatti, FENS Communications Manager, sits down with Vikrant Mahajan and Dr Armando Salinas to explore their exciting new research on Par...

www.podbean.com

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Reposted by Meg Davis

David Baranger @davidbaranger.bsky.social · Jul 8

Our article exploring the neurobiological correlates of prenatal cannabis exposure is now out! "Prenatal cannabis exposure, the brain, and
psychopathology during early adolescence" https://rdcu.be/dMJqH

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Meg Davis @brainsrus.bsky.social · Aug 21

www.sciencedirect.com/science/arti...

New insights into axonal regulators of dopamine transmission in health and disease

Dopamine release in the striatum is credited with being critical to the selection and learning of motivated actions and outcomes. Dysregulation of str…

www.sciencedirect.com

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Meg Davis @brainsrus.bsky.social · Aug 6

x.com/zenbrainest/...

x.com

Meg Davis @brainsrus.bsky.social · Aug 5

www.sciencedirect.com/science/arti...

Building an action circuit with nigrostriatal dopaminergic neurons and striatonigral neurons

In this chapter we first focus our discussions on the late development and maintenance of nigrostriatal dopaminergic neurons (DANs), particularly the …

www.sciencedirect.com

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Reposted by Meg Davis

Jeremy Berg @jeremymberg.bsky.social · Jul 21

My quote of the day

For a successful technology, reality must take precedence over public relations, for Nature cannot be fooled.

Richard Feynman

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Meg Davis @brainsrus.bsky.social · Jul 20

Parvalbumin in blue, NK1R in green. Note the matrix enrichment of the interneurons expressing these markets in DMS.

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Meg Davis @brainsrus.bsky.social · Jul 20

If you inject a CaMk promoter controlled or D1-cre dependent virus into PFC, you get anterograde viral transport AND frequently infect D1 expressing cells in striosomes in medial striatum (red). This is a D1-Cre mouse with a cre dependent AAV9 virus. CaMK is less selective.

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Meg Davis @brainsrus.bsky.social · Jun 22

Perfect. ❤️

Meg Davis @brainsrus.bsky.social · Jun 22

But what about SST/CaMK+ GABA projections? I’ve seen them between CLA and PL www.cell.com/current-biol...

Presynaptic and postsynaptic determinants of claustro-cortical connectivity

de la Torre-Martínez et al. dissect the synaptic organization of claustro-cortical pathways using in vivo and slice recordings combined with optogenetics. By targeting two neuronal populations in the ...

www.cell.com

Meg Davis @brainsrus.bsky.social · Jun 21

sciencemission.com/Alcohol-cons...

Alcohol consumption confers lasting impacts on prefrontal cortical neuron intrinsic excitability and spontaneous neurotransmitter signaling in the aging brain in mice

sciencemission.com

Meg Davis @brainsrus.bsky.social · Jun 18

www.nature.com/articles/s41...

Cannabinoid CB1 receptor-sensitive neurodevelopmental processes and trajectories - Molecular Psychiatry

Molecular Psychiatry - Cannabinoid CB1 receptor-sensitive neurodevelopmental processes and trajectories

www.nature.com

Meg Davis @brainsrus.bsky.social · May 27

Nice work, but what about PrL cortex to DM striosomes vs M1 projections to matrix? Maybe that’s coming… www.science.org/doi/pdf/10.1...

www.science.org

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Meg Davis @brainsrus.bsky.social · Mar 31

www.science.org/doi/10.1126/...

Hedonic eating is controlled by dopamine neurons that oppose GLP-1R satiety

Hedonic eating is defined as food consumption driven by palatability without physiological need. However, neural control of palatable food intake is poorly understood. We discovered that hedonic eatin...

www.science.org

Meg Davis @brainsrus.bsky.social · Mar 24

Cannabinoid receptors in basket cell axons surrounding a hippocampal pyramidal cell. The CB1 receptor is presynaptic and expressed at high levels on GABAergic axons. Not necessarily ‘excitatory’ for the PC. It’s the oscillations!

Meg Davis @brainsrus.bsky.social · Mar 22

www.nature.com/articles/s41...

Molecularly distinct striatonigral neuron subtypes differentially regulate locomotion - Nature Communications

Striatonigral neurons comprise diverse subtypes, yet their specific roles in locomotion regulation are not fully understood. Here, authors demonstrate that the Calb1+ subtype promotes locomotion, whil...

www.nature.com

Meg Davis @brainsrus.bsky.social · Mar 9

Addition to the oddities of transgenics: When breeding NR2A knockouts back in the day, they would have seizures upon introduction. They recovered quickly and resumed the task, but weren’t great breeders or mothers. (Thinking of those of you forced to cull your mice. They have no idea…)

Meg Davis @brainsrus.bsky.social · Mar 9

Useful information for those new to mice. See Jax Labs for more excellent information on all things mouse.

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Meg Davis @brainsrus.bsky.social · Mar 4

This is actually a mini paper shredder for sale at Target. I had to do a double-take. IYKYK

Meg Davis @brainsrus.bsky.social · Mar 2

I’ve attributed the vglut1/2 in the ventral shell to thalamus vs cortex but this could explain why things are weird in medial shell.

Meg Davis @brainsrus.bsky.social · Mar 2

www.biorxiv.org/content/bior...

www.biorxiv.org

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Meg Davis @brainsrus.bsky.social · Mar 2

18f.org

18F: We are dedicated to the American public and we're not done yet

For over 11 years, 18F has been proudly serving the American people to make government technology work better. We are non-partisan civil servants. 18F has worked on hundreds of projects, all designed ...

18f.org

Reposted by Meg Davis

C @notmiddlec.bsky.social · Mar 2

Dr. Francis Collins, a man of science, music, and evangelical Christianity, retired from the NIH yesterday.

This video encapsulates so much of what our country has lost in the first 2 months of 2025.

m.youtube.com/watch?v=kDfN...

Hallelujah - Renee Fleming, Francis Collins & the National Symphony Orchestra

YouTube video by The Kennedy Center

m.youtube.com

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