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Dan Jagger

@auditorynerves.bsky.social

5.9K followers 3K following 1.9K posts

Professor of Cell Physiology, Ear Institute, University College London Research interests: ion channels, hearing/deafness, cilia, rare diseases, neurons, glia www.ucl.ac.uk/ear/research/jaggerlab Insta: @jaggerlab

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Dan Jagger @auditorynerves.bsky.social · Oct 12

We've been looking at historic human inner ear sections - this from the late 1920s.

The histology stain used is written on, in this case "Kulchitsky Weigert Pal". With no training in the area I've looked up what this is, & as a consequence who Kulchitsky was.

Strap in, it's quite a story. 🧪🔬
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Dan Jagger @auditorynerves.bsky.social · 7h

Oh my. How many snakes were needed to make those?

Dan Jagger @auditorynerves.bsky.social · 13h

Link to new study in Science:

A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging.

🧪🧬
www.science.org/doi/10.1126/...

A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging

Efficient DNA repair might make possible the longevity of naked mole-rats. However, whether they have distinctive mechanisms to optimize functions of DNA repair suppressors is unclear. We find that na...

www.science.org

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Dan Jagger @auditorynerves.bsky.social · 13h

Old sausages with teeth.

A new study of the bizarre naked mole rat shows they evolved a DNA repair mechanism that may explain their longevity.

These burrow-dwelling rats have a maximum life span of nearly 40 years, making them the world's longest-lived rodent.

🧪🧬🐀
www.bbc.com/news/article...

Naked mole rats reveal genetic secret to long life

The bald, subterranean rats are the world's longest-lived rodent.

www.bbc.com

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Dan Jagger @auditorynerves.bsky.social · 2d

Open access link to recent related study monitoring egg fertility and embryo survival rates in turtles and tortoises:

Understanding early reproductive failure in turtles and tortoises.
🧪🐢
zslpublications.onlinelibrary.wiley.com/doi/10.1111/...

zslpublications.onlinelibrary.wiley.com

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Dan Jagger @auditorynerves.bsky.social · 2d

Baby giant tortoises thrive in Seychelles after first successful artificial incubation.

Trial that has produced 13 hatchlings could help other threatened species avoid extinction.

🧪🐢
www.theguardian.com/environment/...

Baby giant tortoises thrive in Seychelles after first successful artificial incubation

Exclusive: Trial that has produced 13 hatchlings could help other threatened species avoid extinction

www.theguardian.com

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Dan Jagger @auditorynerves.bsky.social · 2d

Open access link to new study identifying Xiphodracon goldencapensis as a new species of ichthyosaur:

A new long and narrow-snouted ichthyosaur illuminates a complex faunal turnover during an under-sampled Early Jurassic (Pliensbachian) interval. 🧪🦖
onlinelibrary.wiley.com/doi/10.1002/...

A new long and narrow‐snouted ichthyosaur illuminates a complex faunal turnover during an undersampled Early Jurassic (Pliensbachian) interval

Ichthyosaurian faunas before and after the Pliensbachian stage of the Early Jurassic are known from numerous, often complete fossils. The two faunas are very different taxonomically, with only one of...

onlinelibrary.wiley.com

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Dan Jagger @auditorynerves.bsky.social · 2d

A near-complete skeleton found on the UK's Jurassic coast has been identified as a new species of ichthyosaur, a type of prehistoric marine reptile that once ruled the oceans.

It has been named Xiphodracon goldencapensis, or the "sword dragon of Dorset".

🧪⚔️🐉🦖
www.bbc.co.uk/news/article...

Fossil found on UK coast is unique 'sword dragon' species

Scientists say the newly discovered species of marine reptile probably met a grisly end.

www.bbc.co.uk

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Dan Jagger @auditorynerves.bsky.social · 2d

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Dan Jagger @auditorynerves.bsky.social · 2d

Please take a moment to say hello to the newly-discovered bumpy snailfish.

Week in wildlife: a bumpy snailfish, a slow loris & a whistle pig.
🧪🤰🐌🐟
www.theguardian.com/environment/...

Week in wildlife: a bumpy snailfish, a slow loris and a whistle pig

The best of this week’s wildlife photographs from around the world

www.theguardian.com

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Reposted by Dan Jagger

Katie Mack @astrokatie.com · 3d

Today I arrived on the red eye to London Heathrow, took the Tube to my hotel, dropped my bags, hopped on a Lime Bike to cross town, recorded a podcast with New Scientist, then walked an hour (through Hyde Park) back to my hotel. This city is wonderful and I am so tired.

See you tomorrow, London! 😴

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Dan Jagger @auditorynerves.bsky.social · 3d

That's just the worm.

Dan Jagger @auditorynerves.bsky.social · 3d

That classic scientific approach of making the proof. 🧪💊

Aaron Rupar @atrupar.com · 3d

RFK Jr on Tylenol and autism: "It is not proof. We're doing the studies to make the proof."

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Dan Jagger @auditorynerves.bsky.social · 5d

Open access link to new study in Nature Communications:

Sex-stratified genome-wide association meta-analysis of major depressive disorder.

🧪🧠♀️
www.nature.com/articles/s41...

Sex-stratified genome-wide association meta-analysis of major depressive disorder - Nature Communications

Sex differences are well established in the prevalence and symptoms of depression. Here, the authors identify a novel X chromosome variant, greater genetic risk, and stronger links to metabolic traits in females, highlighting the importance of sex-aware approaches.

www.nature.com

Dan Jagger @auditorynerves.bsky.social · 5d

Women carry a higher genetic risk of depression, new study says.

Researchers in Australia find 16 genetic variants linked to depression in women but only eight in men.

🧪🧠♀️ #neuroskyence

www.theguardian.com/science/2025...

Women carry a higher genetic risk of depression, new study says

Researchers in Australia find 16 genetic variants linked to depression in women but only eight in men

www.theguardian.com

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Dan Jagger @auditorynerves.bsky.social · 6d

Nobel Prize in Physiology or Medicine 2025 awarded for discoveries that explain how the immune system attacks hostile infections, but not the body's own cells.

The prize is shared by Japan's Shimon Sakaguchi & US researchers Mary Brunkow & Fred Ramsdell. 🧪

www.bbc.co.uk/news/article...

Nobel Prize for immune system stops destructive rampage

The prize-winning work explains how the immune system attacks hostile infections, but not the body's own cells.

www.bbc.co.uk

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Dan Jagger @auditorynerves.bsky.social · 7d

I'm guessing they're not about to re-enact a Civil War battle?

www.thekingsarmy.org.uk/8203who-we-a...

Who we are and what we do

Who we are and what we do.

www.thekingsarmy.org.uk

Dan Jagger @auditorynerves.bsky.social · 8d

Open access link to new study in Nature Communications:

A safe, T cell-inducing heterologous vaccine against elephant endotheliotropic herpesvirus in a proof-of-concept study.

🧪💉🐘
www.nature.com/articles/s41...

A safe, T cell-inducing heterologous vaccine against elephant endotheliotropic herpesvirus in a proof-of-concept study - Nature Communications

Elephant endotheliotropic herpesvirus (EEHV) haemorrhagic disease is a major threat for juvenile Asian elephants. This study reports a proof-of-concept trial that evaluates the safety and immunogenicity of a vaccine against EEHV.

www.nature.com

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Dan Jagger @auditorynerves.bsky.social · 8d

Researchers have developed a new vaccine to prevent a deadly virus that affects young elephants.

It targets elephant endotheliotropic herpesvirus (EEHV), which is currently a leading cause of death in young Asian elephants.

🧪💉🐘
www.bbc.com/news/article...

Vaccine breakthrough for deadly elephant virus

A vaccine against a deadly disease that affects young elephants is shown to be effective in a world-first trial.

www.bbc.com

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Reposted by Dan Jagger

Paul Macklin @mathcancer.bsky.social · 9d

We're hiring several tenure-track biomedical engineering faculty (at open rank) at IU Bloomington! Come join me in a very multidisciplinary, forward-focused culture that integrates cutting-edge engineering, computing, and artificial intelligence. 🧪

indiana.peopleadmin.com/postings/30517

Multiple, Open Rank, Tenure-Track/Tenured Faculty Positions in Biomedical Engineering

Indiana University Bloomington (IUB) is engaged in a multi-year initiative to increase the breadth and scope of its faculty in biomedical engineering. We are inviting applications for multiple tenure-...

indiana.peopleadmin.com