A model for background selection in non-equilibrium populations https://www.biorxiv.org/content/10.1101/2025.02.19.639084v1

The deadline for the Early Career Award applications has been extended to Dec. 7th! There is still time to apply 🧬🐝🐠🍄

If you are a graduate student or a postdoc interested in #evolution, apply today!

We are accepting applications for the 2025 Evolution Seminar Series Early Career Award here at UW-Madison. Deadline November 30.

evolution.wisc.edu/seminars/ear...

Please share with grad students and postdocs working in evolutionary biology!

Anyone know if archaic hominin sequences (Vindija, Altai Neanderthals, Denisova) have been re-called in reference build 38 and publicly available somewhere?

Our paper on allele frequency transitions under polygenic selection, with a focus on evolve & resequence experiments, is up at Genetics. Led by grad student Nathan Anderson:

urldefense.com/v3/__https:/...

We are accepting applications for the 2025 Evolution Seminar Series Early Career Award here at UW-Madison. Deadline November 30.

evolution.wisc.edu/seminars/ear...

Please share with grad students and postdocs working in evolutionary biology!

Their paper [which I enjoyed very much] presents some nice pop-gen insights into expected patterns of variation under reciprocal introgression, and raises some interesting Qs about post-admixture selection in humans and Neanderthals.

Read it here: www.cell.com/current-biol...

I wrote a review of the recent paper from Harris, Platt, Tishkoff et al. on early human-to-Neanderthal introgression, out as a Dispatch in Current Biology.

Quick read, free link: authors.elsevier.com/a/1i7L53QW8S...

This is a really interesting paper: www.cell.com/current-biol...

Early human introgression into Neanderthals around 250 thousand years ago, resulting in up to 6% human DNA in Neanderthals. And then evidence that human-introgressed alleles were selected against after their introduction.

So for K=1, it's trivial ({} and {{1}}). For K=2: {}, {{1}}, {{2}}, {{1, 2}}, and {{1}, {2}, {1, 2}}. I thought I had a nice iterative method worked out, but it starts to blow up around K=5 checking all the duplicated solutions, even though the final number is not that huge.

What I thought was an easy algebra problem, that is giving me a headache: I am looking for a way to generate all subsets of the power set for a given K that are closed under union of disjoint sets and complementation of nested sets.