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amundadottir.bsky.social
Laufey Amundadottir
@amundadottir.bsky.social
220 followers 98 following 3 posts
Genetics and genomics of pancreatic cancer. Opinions expressed are my own
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amundadottir.bsky.social
Laufey Amundadottir @amundadottir.bsky.social · 4d
So excited that our manuscript is now online! Led by the super talented @junzhong.bsky.social & Aidan O'Brien in my lab with lots of help from Minal Patel @kconnelly92.bsky.social Jason Hoskins @efsunarda.bsky.social @struangrant.bsky.social and others. Very grateful to our team and collaborators!!
Large-scale multiomic analysis identifies non-coding somatic driver mutations and nominates ZFP36L2 as a driver gene for pancreatic ductal adenocarcinoma
Background The identification and characterisation of somatic cancer driver mutations in the non-coding genome remains challenging. Objective To broadly characterise non-coding driver mutations for p...
gut.bmj.com
2 7
Reposted by Laufey Amundadottir
junzhong.bsky.social
Jun Zhong @junzhong.bsky.social · 5d
Always one of the best moments in research and very pound to be in the @amundadottir.bsky.social team!
struangrant.bsky.social
Struan Grant @struangrant.bsky.social · 5d
Congratulations to the @amundadottir.bsky.social team for their #Gut paper reporting a large-scale multiomic analysis of pancreatic ductal adenocarcinoma. Delighted to contribute along with @adwellspenn.bsky.social. @chopresearch.bsky.social @penngenetics.bsky.social

gut.bmj.com/content/earl...
Large-scale multiomic analysis identifies non-coding somatic driver mutations and nominates ZFP36L2 as a driver gene for pancreatic ductal adenocarcinoma
Background The identification and characterisation of somatic cancer driver mutations in the non-coding genome remains challenging. Objective To broadly characterise non-coding driver mutations for p...
gut.bmj.com
1 2 7
amundadottir.bsky.social
Laufey Amundadottir @amundadottir.bsky.social · May 2
www.nature.com/articles/s41...
Allelic effects on KLHL17 expression underlie a pancreatic cancer genome-wide association signal at chr1p36.33 - Nature Communications
Allele-preferential transcription factor binding can influence pancreatic ductal adenocarcinoma risk loci function. Here, the authors show allele-specific JunB and JunD binding at chr1p36.33 and propo...
www.nature.com
1
Reposted by Laufey Amundadottir
amundadottir.bsky.social
Laufey Amundadottir @amundadottir.bsky.social · May 2
Very excited to share our research identifying a mechanism underlying PDAC risk at chr1p36.33 via KLHL17 gene regulation. Project led by a super talented Research Fellow @kconnelly92.bsky.social who is on the job market. Now online at Nature Communications
1 1 4
amundadottir.bsky.social
Laufey Amundadottir @amundadottir.bsky.social · May 2
Very excited to share our research identifying a mechanism underlying PDAC risk at chr1p36.33 via KLHL17 gene regulation. Project led by a super talented Research Fellow @kconnelly92.bsky.social who is on the job market. Now online at Nature Communications
1 1 4