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alexanderford25.bsky.social @alexanderford25.bsky.social · 6d

Our latest network meta-analysis looking at efficacy of behavioural therapies in #IBS is now published online in
@LancetGastroHep

sciencedirect.com/science/arti...

Efficacy of behavioural therapies for irritable bowel syndrome: a systematic review and network meta-analysis

Irritable bowel syndrome (IBS) management guidelines recommend that behavioural therapies, particularly brain–gut behaviour therapies, should be consi…

sciencedirect.com

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The Lancet Gastroenterology & Hepatology @lancetgastrohep.bsky.social · 6d

New research - Efficacy of behavioural therapies for irritable bowel syndrome: a systematic review and network meta-analysis

www.thelancet.com/journals/lan...

#GastroSky #MedSky @alexanderford25.bsky.social @romegastropsych.bsky.social

Efficacy of behavioural therapies for irritable bowel syndrome: a systematic review and network meta-analysis

Several behavioural therapies are efficacious for global symptoms in IBS, although the most evidence exists for those classed as brain–gut behaviour therapies. However, certainty in the evidence for a...

www.thelancet.com

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Rob Brierley @robbrierley.bsky.social · 22d

New @lancetgastrohep.bsky.social

Non-inferiority of lyophilised faecal filtrate vs lyophilised donor stool was not established for the prevention of C difficile recurrence over 8 weeks

👉 Live 🦠 crucial in mediating clinical efficacy

www.thelancet.com/journals/lan...

#GISky #IDSky #MicroSky #FMT

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Johannah Ruddy @johannahruddy.bsky.social · 22d

Medical students often view IBS as “less real” and harder to treat than IBD, biases that deepen with training. Since physician perceptions shape care, we must intervene early with education that frames IBS as legitimate and models compassionate, evidence-based care.

Medical students' knowledge and perception of irritable bowel syndrome in comparison to inflammatory bowel disease - PubMed

Biases observed in gastroenterologists toward patients with IBS originate as early as the beginning of medical school, including seeing IBS as a "less real" disease and more difficult to treat. Earlier educational interventions may be helpful in identifying and addressing these biases.

pubmed.ncbi.nlm.nih.gov

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The Lancet Gastroenterology & Hepatology @lancetgastrohep.bsky.social · Jun 5

Our July 2025 issue is out now at www.thelancet.com/gastrohep!

The issue includes content on alcohol and health, eosinophilic oesophagitis, hepatocellular carcinoma, pancreatic cancer, viral hepatitis, and much more...

#gastrosky #oncsky #idsky #medsky

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Rob Brierley @robbrierley.bsky.social · Jun 5

Our latest issue is out now!

👇👇👇

#gastrosky #medsky #oncsky #hepsky

The Lancet Gastroenterology & Hepatology @lancetgastrohep.bsky.social · Jun 5

Our July 2025 issue is out now at www.thelancet.com/gastrohep!

The issue includes content on alcohol and health, eosinophilic oesophagitis, hepatocellular carcinoma, pancreatic cancer, viral hepatitis, and much more...

#gastrosky #oncsky #idsky #medsky

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The BMJ @bmj.com · May 21

Obituary for Rob Sapsford (1964-2024): Leeds cardiologist whose breadth of knowledge and sense of humour have left a huge hole.

Sapsford's warmth meant his office became an unofficial break room as colleagues would often pop in for a chat
www.bmj.com/content/389/...

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Rob Brierley @robbrierley.bsky.social · May 15

For patients with eosinophilic oesophagitis, etrasimod 2 mg once-daily treatment resulted in a significantly greater percentage decrease from baseline in oesophageal PEC versus placebo

#gastrosky #medsky

The Lancet Gastroenterology & Hepatology @lancetgastrohep.bsky.social · May 15

New research - Etrasimod as a treatment for eosinophilic oesophagitis (VOYAGE): a double-blind, placebo-controlled, randomised, phase 2 trial

www.thelancet.com/journals/lan...

#gastrosky #medsky

Etrasimod as a treatment for eosinophilic oesophagitis (VOYAGE): a double-blind, placebo-controlled, randomised, phase 2 trial

Etrasimod led to sustained histological and endoscopic improvements in eosinophilic oesophagitis over 52 weeks, symptom improvement in patients without dilation, and was well tolerated. This trial pro...

www.thelancet.com

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alexanderford25.bsky.social @alexanderford25.bsky.social · May 8

Back to back with our meta-analysis of gut-brain neuromodulators in #IBS

www.thelancet.com/journals/lan...

Efficacy of gut–brain neuromodulators in irritable bowel syndrome: an updated systematic review and meta-analysis

Some gut–brain neuromodulators are efficacious in reducing global symptoms and abdominal pain in IBS. The findings support guidelines that recommend use of tricyclic antidepressants for ongoing global...

www.thelancet.com

1

alexanderford25.bsky.social @alexanderford25.bsky.social · May 8

And now published in this month’s issue of the journal

www.thelancet.com/journals/lan...

Efficacy of dietary interventions in irritable bowel syndrome: a systematic review and network meta-analysis

In terms of dietary interventions for IBS, the most evidence exists for a low FODMAP diet, but other promising therapies are emerging and should be the subject of further study.

www.thelancet.com

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alexanderford25.bsky.social @alexanderford25.bsky.social · May 8

Nice coverage @lancetgastrohep.bsky.social

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The Lancet Gastroenterology & Hepatology @lancetgastrohep.bsky.social · May 8

What is the best diet for IBS?

www.medscape.com/viewarticle/...

via @medscape.com

#gastrosky #medsky @alexanderford25.bsky.social

What is the Best Diet for IBS?

A network meta-analysis of 28 trials evaluating dietary interventions for IBS found that reducing starch and sucrose ranked first in improving global symptoms.

www.medscape.com

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Katrina Ray @heykatray.bsky.social · Apr 26

#gastrosky

Nature Reviews Gastroenterology & Hepatology @natrevgastrohep.nature.com · Apr 26

New online! Common misconceptions and controversies in the management of irritable bowel syndrome

Common misconceptions and controversies in the management of irritable bowel syndrome

Nature Reviews Gastroenterology & Hepatology, Published online: 25 April 2025; doi:10.1038/s41575-025-01065-9This Perspective discusses misconceptions and controversies in the clinical management of irritable bowel syndrome (IBS), including diagnosis, testing and treatment, among others. Areas in which issues have been resolved and those that require further research and clarification are highlighted.

www.nature.com

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Nature Reviews Gastroenterology & Hepatology @natrevgastrohep.nature.com · Apr 26

New online! Common misconceptions and controversies in the management of irritable bowel syndrome

Common misconceptions and controversies in the management of irritable bowel syndrome

Nature Reviews Gastroenterology & Hepatology, Published online: 25 April 2025; doi:10.1038/s41575-025-01065-9This Perspective discusses misconceptions and controversies in the clinical management of irritable bowel syndrome (IBS), including diagnosis, testing and treatment, among others. Areas in which issues have been resolved and those that require further research and clarification are highlighted.

www.nature.com

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The Lancet Gastroenterology & Hepatology @lancetgastrohep.bsky.social · Apr 25

New @lancetchildadol.bsky.social - Efficacy of interventions for the treatment of irritable bowel syndrome, functional abdominal pain—not otherwise specified, and abdominal migraine in children

www.thelancet.com/journals/lan...

#IBSAwarenessMonth #GastroSky #MedSky #IBS #WorldIBSDay

Efficacy of interventions for the treatment of irritable bowel syndrome, functional abdominal pain—not otherwise specified, and abdominal migraine in children: a systematic review and network meta-ana...

Hypnotherapy and CBT show moderate certainty for treatment efficacy with clinically relevant effect sizes. No conclusions can be made about the other therapies and treatment success due to very low ev...

www.thelancet.com

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The Lancet Gastroenterology & Hepatology @lancetgastrohep.bsky.social · Apr 19

New Editorial - Breaking the cycle: time to invest in IBS

www.thelancet.com/journals/lan...

#WorldIBSDay #IBSAwarenessMonth #IBS #IrritableBowelSyndrome #GastroSky #MedSky

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alexanderford25.bsky.social @alexanderford25.bsky.social · Apr 19

Breaking the cycle: time to invest in IBS - The Lancet Gastroenterology & Hepatology www.thelancet.com/journals/lan...

Breaking the cycle: time to invest in IBS

April marks Irritable Bowel Syndrome (IBS) Awareness Month, and April 19 World IBS Day, together aiming to raise awareness of this debilitating condition. Characterised by abdominal pain and a change ...

www.thelancet.com

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The Lancet Gastroenterology & Hepatology @lancetgastrohep.bsky.social · Apr 19

New research - Cuffe et al - Efficacy of dietary interventions in irritable bowel syndrome: a systematic review and network meta-analysis

www.thelancet.com/journals/lan...

#WorldIBSDay #IBSAwarenessMonth #GastroSky #MedSky #IBS #IrritableBowelSyndrome

Efficacy of dietary interventions in irritable bowel syndrome: a systematic review and network meta-analysis

In terms of dietary interventions for IBS, the most evidence exists for a low FODMAP diet, but other promising therapies are emerging and should be the subject of further study.

www.thelancet.com

1 3 5

Reposted

The Lancet Gastroenterology & Hepatology @lancetgastrohep.bsky.social · Apr 19

New research - Khasanaweh et al - Efficacy of gut–brain neuromodulators in irritable bowel syndrome: an updated systematic review and meta-analysis

www.thelancet.com/journals/lan...

#WorldIBSDay #IBSAwarenessMonth #IrritableBowelSyndrome #IBS #GastroSky #MedSky

Efficacy of gut–brain neuromodulators in irritable bowel syndrome: an updated systematic review and meta-analysis

Some gut–brain neuromodulators are efficacious in reducing global symptoms and abdominal pain in IBS. The findings support guidelines that recommend use of tricyclic antidepressants for ongoing global...

www.thelancet.com

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alexanderford25.bsky.social @alexanderford25.bsky.social · Apr 19

Back to back papers from our group in @lancetgastrohep.bsky.social on #WorldIBSday 2025

Read them here:

www.thelancet.com/journals/lan...

www.thelancet.com/journals/lan...

Efficacy of gut–brain neuromodulators in irritable bowel syndrome: an updated systematic review and meta-analysis

Some gut–brain neuromodulators are efficacious in reducing global symptoms and abdominal pain in IBS. The findings support guidelines that recommend use of tricyclic antidepressants for ongoing global...

www.thelancet.com

1 4

alexanderford25.bsky.social @alexanderford25.bsky.social · Apr 19

On #WorldIBSDay2025 our updated meta-analysis of gut brain neuromodulators in #IBS is published in
@lancetgastrohep.bsky.social

www.thelancet.com/journals/lan...

Efficacy of gut–brain neuromodulators in irritable bowel syndrome: an updated systematic review and meta-analysis

Some gut–brain neuromodulators are efficacious in reducing global symptoms and abdominal pain in IBS. The findings support guidelines that recommend use of tricyclic antidepressants for ongoing global...

www.thelancet.com

1 2

alexanderford25.bsky.social @alexanderford25.bsky.social · Apr 19

On #WorldIBSDay2025 our updated network meta-analysis of dietary interventions in #IBS is published in
@lancetgastrohep.bsky.social

www.thelancet.com/journals/lan...

Efficacy of dietary interventions in irritable bowel syndrome: a systematic review and network meta-analysis

In terms of dietary interventions for IBS, the most evidence exists for a low FODMAP diet, but other promising therapies are emerging and should be the subject of further study.

www.thelancet.com

1 1

alexanderford25.bsky.social @alexanderford25.bsky.social · Apr 8

Predictors of response to low-dose amitriptyline for irritable bowel syndrome and efficacy and tolerability according to subtype: post hoc analyses from the ATLANTIS trial gut.bmj.com/content/74/5...

Latest paper from the
@AtlantisTrial
in this months edition of
@Gut_BMJ

Predictors of response to low-dose amitriptyline for irritable bowel syndrome and efficacy and tolerability according to subtype: post hoc analyses from the ATLANTIS trial

Background Low-dose amitriptyline, a tricyclic antidepressant (TCA), was superior to placebo for irritable bowel syndrome (IBS) in the AmitripTyline at Low-dose ANd Titrated for Irritable bowel syndro...

gut.bmj.com

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American Gastroenterological Association (AGA) @amergastroassn.bsky.social · Apr 1

#DYK April is #IBSAwareness Month?

We join the IBS community and caretakers to raise awareness about this GI condition. IBS affects all patients differently. Use our clinical guidance for recommendations to treat this common GI condition: gastro.org/news/ibs-cli....

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Heidi Staudacher Phd AdvAPD @hmstaudacher.bsky.social · Mar 24

A must-listen for anyone working with people with DGBI 👇🏼 Great summary and experience from Alex Ford podcasts.apple.com/au/podcast/t...

#04: Professor Alex Ford - Navigating disorders of gut-brain interaction and IBS

Podcast Episode · Two guys talking **it - A Gastroenterology and Hepatology podcast · 22/01/2025 · 1h 11m

podcasts.apple.com

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